Pharmacological Development of Target-Specific Delocalized Lipophilic Cation-Functionalized Carboranes for Cancer Therapy

New Strategies in Cancer Nanomedicine

(2016) Rong Tong et al.   Annual Review of Pharmacology and Toxicology

Toward a Better Understanding of the Complexity of Cancer Drug Resistance

(2016) Michael M. Gottesman et al.   Annual Review of Pharmacology and Toxicology

Enabling personalized cancer medicine decisions: The challenging pharmacological approach of PBPK models for nanomedicine and pharmacogenomics (Review)

(2016) IOANNIS S. VIZIRIANAKIS et al.   ONCOLOGY REPORTS

The BCL-2 protein family, BH3-mimetics and cancer therapy

(2015) A R D Delbridge et al.   CELL DEATH AND DIFFERENTIATION

Membrane Permeable Lipophilic Cations as Mitochondrial Directing Groups

(2015) Joseph Madak et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy

(2015) Maja Sochalska et al.   FEBS Journal

Treatment Strategies that Enhance the Efficacy and Selectivity of Mitochondria-Targeted Anticancer Agents

(2015) Josephine Modica-Napolitano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

p53, a translational regulator: contribution to its tumour-suppressor activity

(2015) V Marcel et al.   ONCOGENE

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Getting to the Source: Selective Drug Targeting of Cancer Stem Cells

(2014) Fatima Ismail et al.   ChemMedChem

Dequalinium induces cytotoxicity in human leukemia NB4 cells by downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways and potentiation of specific inhibitors of these pathways

(2014) Ana I. García-Pérez et al.   LEUKEMIA RESEARCH

New Molecules and Old Drugs as Emerging Approaches to Selectively Target Human Glioblastoma Cancer Stem Cells

(2014) Roberto Würth et al.   Biomed Research International

Towards boron neutron capture therapy: The formulation and preliminary in vitro evaluation of liposomal vehicles for the therapeutic delivery of the dequalinium salt of bis-nido-carborane

(2013) Dimitrios Theodoropoulos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The prognostic value of apoptotic and proliferative markers in breast cancer

(2013) Charla C. Engels et al.   BREAST CANCER RESEARCH AND TREATMENT

Effects ofTP53mutational status on gene expression patterns across 10 human cancer types

(2013) Neha Parikh et al.   JOURNAL OF PATHOLOGY

Personalized nanomedicine: paving the way to the practical clinical utility of genomics and nanotechnology advancements

(2012) Ioannis S. Vizirianakis et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeting cancer cell mitochondria as a therapeutic approach

(2012) Shijun Wen et al.   Future Medicinal Chemistry

Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?

(2012) P. Borst   Open Biology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Baicalin increases VEGF expression and angiogenesis by activating the ERR /PGC-1  pathway

(2010) K. Zhang et al.   CARDIOVASCULAR RESEARCH

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆

(2009) Divya Pathania et al.   ADVANCED DRUG DELIVERY REVIEWS

WNT16B Is a New Marker of Cellular Senescence That Regulates p53 Activity and the Phosphoinositide 3-Kinase/AKT Pathway

(2009) R. Binet et al.   CANCER RESEARCH

Carborane-based derivatives of delocalised lipophilic cations for boron neutron capture therapy: synthesis and preliminary in vitro evaluation

(2008) Gianpiero Calabrese et al.   JOURNAL OF MATERIALS CHEMISTRY

From delocalized lipophilic cations to hypoxia: Blocking tumor cell mitochondrial function leads to therapeutic gain with glycolytic inhibitors

(2008) Metin Kurtoglu et al.   MOLECULAR NUTRITION & FOOD RESEARCH