Effects of Histidine and Sucrose on the Biophysical Properties of a Monoclonal Antibody
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Effects of Histidine and Sucrose on the Biophysical Properties of a Monoclonal Antibody
Authors
Keywords
excipients, formulation, light scattering, monoclonal antibody, physical characterization
Journal
PHARMACEUTICAL RESEARCH
Volume 34, Issue 3, Pages 629-639
Publisher
Springer Nature
Online
2016-12-30
DOI
10.1007/s11095-016-2092-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Biophysical stability of hyFc fusion protein with regards to buffers and various excipients
- (2016) Jun Yeul Lim et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Improved Stability of a Model IgG3 by DoE-Based Evaluation of Buffer Formulations
- (2016) Brittany K. Chavez et al. Biomed Research International
- Intermolecular Interactions and the Viscosity of Highly Concentrated Monoclonal Antibody Solutions
- (2015) Elaheh Binabaji et al. PHARMACEUTICAL RESEARCH
- Evaluation of etanercept stability as exposed to various sugars with biophysical assessment
- (2014) Dae Gon Lim et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The osmotic pressure of highly concentrated monoclonal antibody solutions: Effect of solution conditions
- (2013) Elaheh Binabaji et al. BIOTECHNOLOGY AND BIOENGINEERING
- The multiple roles of histidine in protein interactions
- (2013) Si-Ming Liao et al. Chemistry Central Journal
- Characterization of antibody–polyol interactions by static light scattering: Implications for physical stability of protein formulations
- (2013) Shermeen A. Abbas et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Effects of Temperature and Osmolytes on Competing Degradation Routes for an IgG1 Antibody
- (2013) Christopher J. Roberts et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Stability of Monoclonal Antibodies at High-Concentration: Head-to-Head Comparison of the IgG1 and IgG4 Subclass
- (2013) Martin S. Neergaard et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Both protein adsorption and aggregation contribute to shear yielding and viscosity increase in protein solutions
- (2013) Maria Monica Castellanos et al. Soft Matter
- Investigation of Histidine Stabilizing Effects on LDH During Freeze-Drying
- (2012) Anas Al-Hussein et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Protein–excipient interactions: Mechanisms and biophysical characterization applied to protein formulation development
- (2011) Tim J. Kamerzell et al. ADVANCED DRUG DELIVERY REVIEWS
- Protein Instability and Immunogenicity: Roadblocks to Clinical Application of Injectable Protein Delivery Systems for Sustained Release
- (2011) Wim Jiskoot et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Behavior of Monoclonal Antibodies: Relation Between the Second Virial Coefficient (B 2) at Low Concentrations and Aggregation Propensity and Viscosity at High Concentrations
- (2011) Shuntaro Saito et al. PHARMACEUTICAL RESEARCH
- Attractive Interactions between Side Chains of Histidine-Histidine and Histidine-Arginine-Based Cationic Dipeptides in Water
- (2010) Jan Heyda et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Understanding and Modulating Opalescence and Viscosity in a Monoclonal Antibody Formulation
- (2009) Branden A. Salinas et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started