Determination of process variables affecting drug particle attrition within multi-component blends during powder feed transmission

Investigation into process-induced de-aggregation of cohesive micronised API particles

(2015) Magnus Hoffmann et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Application of Image-Based Particle Size and Shape Characterization Systems in the Development of Small Molecule Pharmaceuticals

(2015) John F. Gamble et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Scale-up of agitated drying: Effect of shear stress and hydrostatic pressure on active pharmaceutical ingredient powder properties

(2014) Brenda Remy et al.   AICHE JOURNAL

Monitoring process induced attrition of drug substance particles within formulated blends

(2014) John F. Gamble et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Application of imaging based tools for the characterisation of hollow spray dried amorphous dispersion particles

(2014) John F. Gamble et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A proposal for a drug product Manufacturing Classification System (MCS) for oral solid dosage forms

(2014) Michael Leane et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Investigation of factors affecting isolation of needle-shaped particles in a vacuum-agitated filter drier through non-invasive measurements by Raman spectrometry

(2013) Peter Hamilton et al.   CHEMICAL ENGINEERING SCIENCE

Development and Application of Laboratory Tools To Predict Particle Properties upon Scale-Up in Agitated Filter-Dryers

(2013) David am Ende et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

On the Fracture of Pharmaceutical Needle-Shaped Crystals during Pressure Filtration: Case Studies and Mechanistic Understanding

(2012) Claire S. MacLeod et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Effect of feed frame design and operating parameters on powder attrition, particle breakage, and powder properties

(2012) Rafael Mendez et al.   POWDER TECHNOLOGY

Laboratory methods for assessing API sensitivity to mechanical stress during agitated drying

(2011) David J. Lamberto et al.   CHEMICAL ENGINEERING SCIENCE

An investigation into the impact of magnesium stearate on powder feeding during roller compaction

(2011) Jason Dawes et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Impact of Laboratory Vacuum Contact Drying on Material Drying Rates and Physical Properties

(2011) P. Kontcho Kom et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Impact of agitated drying on the powder properties of an active pharmaceutical ingredient

(2011) E. Kougoulos et al.   POWDER TECHNOLOGY

Investigation into the impact of sub-populations of agglomerates on the particle size distribution and flow properties of conventional microcrystalline cellulose grades

(2010) John F. Gamble et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY