Hemophagocytic lymphohistiocytosis: Pathogenesis, diagnosis, and management

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborat

(2016) Angelo Ravelli et al.   Arthritis & Rheumatology

Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion

(2015) W. A. Spessott et al.   BLOOD

Malignancy-associated haemophagocytic lymphohistiocytosis in children and adolescents

(2015) Kai Lehmberg et al.   BRITISH JOURNAL OF HAEMATOLOGY

Macrophage Activation Syndrome

(2015) Angelo Ravelli et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Novel mutations in TNFRSF7/CD27: Clinical, immunologic, and genetic characterization of human CD27 deficiency

(2015) Omar K. Alkhairy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Management of neonatal herpes simplex virus infection and exposure

(2014) Swetha G Pinninti et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Prognostic factors of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children: Report of the Japan Histiocytosis Study Group

(2014) Kazuhiro Kogawa et al.   PEDIATRIC BLOOD & CANCER

Current research on chronic active Epstein-Barr virus infection in Japan

(2014) Shigeyoshi Fujiwara et al.   PEDIATRICS INTERNATIONAL

Clinical Features, Treatment, and Outcome of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A Multinational, Multicenter Study of 362 Patients

(2014) Francesca Minoia et al.   Arthritis & Rheumatology

Lymphoma-associated hemophagocytic lymphohistiocytosis: experience in adults from a single institution

(2013) Jui-Ting Yu et al.   ANNALS OF HEMATOLOGY

Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8+ T cells and dendritic cells

(2013) C. E. Terrell et al.   BLOOD

Treatment of Epstein Barr virus-induced haemophagocytic lymphohistiocytosis with rituximab-containing chemo-immunotherapeutic regimens

(2013) DeepakBabu Chellapandian et al.   BRITISH JOURNAL OF HAEMATOLOGY

Feasibility of reduced-intensity conditioning followed by unrelated cord blood transplantation for primary hemophagocytic lymphohistiocytosis: a nationwide retrospective analysis in Japan

(2013) Akihisa Sawada et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Are regimens containing rituximab effective in the initial treatment of Epstein–Barr virus-positive natural killer cell lymphoproliferative disease-associated hemophagocytic lymphohistiocytosis?

(2013) Shinsaku Imashuku et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Clinical characteristics and outcomes of chédiak-Higashi syndrome: A nationwide survey of Japan

(2013) Kozo Nagai et al.   PEDIATRIC BLOOD & CANCER

A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes

(2012) Y. T. Bryceson et al.   BLOOD

Hemophagocytic Lymphohistiocytosis With Isolated Central Nervous System Reactivation and Optic Nerve Involvement

(2012) Kok Wee Chong et al.   JOURNAL OF CHILD NEUROLOGY

Clinical and Genetic Characteristics of XIAP Deficiency in Japan

(2012) Xi Yang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Clinical features and outcome of X-linked lymphoproliferative syndrome type 1 (SAP deficiency) in Japan identified by the combination of flow cytometric assay and genetic analysis

(2012) Hirokazu Kanegane et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

SAP and XIAP deficiency in hemophagocytic lymphohistiocytosis

(2012) Xi Yang et al.   PEDIATRICS INTERNATIONAL

Rapid diagnosis of FHL3 by flow cytometric detection of intraplatelet Munc13-4 protein

(2011) Y. Murata et al.   BLOOD

Association of IRF5 Polymorphisms with Susceptibility to Hemophagocytic Lymphohistiocytosis in Children

(2011) Masakatsu Yanagimachi et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Hemophagocytic lymphohistiocytosis after hematopoietic stem cell transplantation in children: A nationwide survey in Japan

(2011) Takeshi Asano et al.   PEDIATRIC BLOOD & CANCER

Treatment choice of immunotherapy or further chemotherapy for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis

(2011) Akira Shiraishi et al.   PEDIATRIC BLOOD & CANCER

Clinical Significance of Cloned Expansion and CD5 Down‐Regulation in Epstein‐Barr Virus (EBV)–Infected CD8+T Lymphocytes in EBV‐Associated Hemophagocytic Lymphohistiocytosis

(2010) Akiko Toga et al.   JOURNAL OF INFECTIOUS DISEASES

Hemophagocytic lymphohistiocytosis with MUNC13-4 gene mutation or reduced natural killer cell function prior to onset of childhood leukemia

(2010) Tamara Y. Chang et al.   PEDIATRIC BLOOD & CANCER

Subtypes of Familial Hemophagocytic Lymphohistiocytosis in Japan Based on Genetic and Functional Analyses of Cytotoxic T Lymphocytes

(2010) Kozo Nagai et al.   PLoS One

Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11

(2009) Udo zur Stadt et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Macrophage activation syndrome in juvenile systemic lupus erythematosus: A multinational multicenter study of thirty-eight patients

(2009) Alessandro Parodi et al.   ARTHRITIS AND RHEUMATISM

Girls homozygous for an IL-2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation

(2009) Kirsten Huck et al.   JOURNAL OF CLINICAL INVESTIGATION

Characteristics of Hemophagocytic Lymphohistiocytosis in Neonates: A Nationwide Survey in Japan

(2009) Nobuhiro Suzuki et al.   JOURNAL OF PEDIATRICS

Allogeneic hematopoietic stem cell transplantation for Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative disease in Japan

(2008) Emiko Sato et al.   AMERICAN JOURNAL OF HEMATOLOGY

Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis

(2008) AnnaCarin Horne et al.   BRITISH JOURNAL OF HAEMATOLOGY