Serological and genetic complement alterations in infection-induced and complement-mediated hemolytic uremic syndrome

Systemic complement activation and complement gene analysis in enterohaemorrhagicEscherichia coli-associated paediatric haemolytic uraemic syndrome

(2016) Thurid Ahlenstiel-Grunow et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Complement activation patterns in atypical haemolytic uraemic syndrome during acute phase and in remission

(2015) E. B. Volokhina et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Dynamics of complement activation in aHUS and how to monitor eculizumab therapy

(2014) M. Noris et al.   BLOOD

Hemolytic uremic syndrome with simultaneous Shiga toxin producing Escherichia coli and complement abnormalities

(2014) Nicole McCoy et al.   BMC Pediatrics

Factors determining penetrance in familial atypical haemolytic uraemic syndrome

(2014) Francis H Sansbury et al.   JOURNAL OF MEDICAL GENETICS

Syndromes of Thrombotic Microangiopathy

(2014) James N. George et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of Complement in Enterohemorrhagic Escherichia coli–Induced Hemolytic Uremic Syndrome

(2014) Reinhard Würzner et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Two Patients With History of STEC-HUS, Posttransplant Recurrence and Complement Gene Mutations

(2013) M. Alberti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Comprehensive Genetic Analysis of Complement and Coagulation Genes in Atypical Hemolytic Uremic Syndrome

(2013) F. Bu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

An international serum standard for application in assays to detect human complement activation products

(2013) Grethe Bergseth et al.   MOLECULAR IMMUNOLOGY

Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration

(2013) Johanna M Seddon et al.   NATURE GENETICS

Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome

(2013) Mathieu Lemaire et al.   NATURE GENETICS

Outbreak of Escherichia coli O104:H4 haemolytic uraemic syndrome in France: outcome with eculizumab

(2013) Y. Delmas et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

(2013) C.M. Legendre et al.   NEW ENGLAND JOURNAL OF MEDICINE

Combined Pulmonary Hypertension and Renal Thrombotic Microangiopathy in Cobalamin C Deficiency

(2013) M. Komhoff et al.   PEDIATRICS

Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic–uraemic syndrome: an analysis of the German STEC-HUS registry

(2012) Jan T. Kielstein et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Novel C3 mutation p.Lys65Gln in aHUS affects complement factor H binding

(2012) Elena Volokhina et al.   PEDIATRIC NEPHROLOGY

Eculizumab as rescue therapy for atypical hemolytic uremic syndrome with normal platelet count

(2012) Eiske M. Dorresteijn et al.   PEDIATRIC NEPHROLOGY

The challenge of managing hemophilia A and STEC-induced hemolytic uremic syndrome

(2012) Dineke Westra et al.   PEDIATRIC NEPHROLOGY

Atypical hemolytic uremic syndrome in children: complement mutations and clinical characteristics

(2012) Lianne M. Geerdink et al.   PEDIATRIC NEPHROLOGY

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study

(2012) J. Menne et al.   BMJ-British Medical Journal

Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome

(2011) A.-l. Stahl et al.   BLOOD

Alternative Pathway Activation of Complement by Shiga Toxin Promotes Exuberant C3a Formation That Triggers Microvascular Thrombosis

(2011) M. Morigi et al.   JOURNAL OF IMMUNOLOGY

Characterization of the New Serum Protein Reference Material ERM-DA470k/IFCC: Value Assignment by Immunoassay

(2010) I. Zegers et al.   CLINICAL CHEMISTRY

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

(2010) M. Noris et al.   Clinical Journal of the American Society of Nephrology

EspP, a Serine Protease of Enterohemorrhagic Escherichia coli, Impairs Complement Activation by Cleaving Complement Factors C3/C3b and C5

(2010) D. Orth et al.   INFECTION AND IMMUNITY

Genetic disorders in complement (regulating) genes in patients with atypical haemolytic uraemic syndrome (aHUS)

(2010) D. Westra et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Alternative Pathway of Complement in Children with Diarrhea-Associated Hemolytic Uremic Syndrome

(2009) J. M. Thurman et al.   Clinical Journal of the American Society of Nephrology

Shiga Toxin Activates Complement and Binds Factor H: Evidence for an Active Role of Complement in Hemolytic Uremic Syndrome

(2009) Dorothea Orth et al.   JOURNAL OF IMMUNOLOGY

Structure of complement fragment C3b–factor H and implications for host protection by complement regulators

(2009) Jin Wu et al.   NATURE IMMUNOLOGY

Thrombomodulin Mutations in Atypical Hemolytic–Uremic Syndrome

(2009) Mieke Delvaeye et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of a Factor H Mutation With Hemolytic Uremic Syndrome Following a Diarrheal Illness

(2008) Matthew M. Edey et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome

(2008) V. Fremeaux-Bacchi et al.   BLOOD

Guideline for the investigation and initial therapy of diarrhea-negative hemolytic uremic syndrome

(2008) Gema Ariceta et al.   PEDIATRIC NEPHROLOGY

Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome

(2007) C. J. Fang et al.   BLOOD