Article
Fisheries
Zhao Zhang, Haibo Cui, Zhiqiang Zhang, Shenye Qu, Gaoxue Wang, Fei Ling
Summary: The study investigated the pharmacokinetics of magnolol in goldfish following different administration routes and found that oral administration of magnolol effectively controlled Ichthyophthirius multifiliis infection. The results indicated that magnolol could be a potential treatment for fish infections caused by I. multifiliis.
Article
Fisheries
Nermeen M. Abu-Elala, Marwa M. Attia, Reham M. Abd-Elsalam, Abdelrhman Gamal, Nehal A. Younis
Summary: Co-infections with various ectoparasites and bacteria were found in a private Nile tilapia farm in Egypt, leading to high fish mortality. The application of peracetic acid effectively reduced the infection by Aeromonas hydrophila and improved the survivability of Nile tilapia by eradicating the ciliated protozoans Ichthyophthirius multifiliis and Trichodina centrostrigeata.
Article
Immunology
V. Kumar, B. K. Das, H. S. Swain, H. Chowdhury, S. Roy, A. K. Bera, R. Das, S. N. Parida, S. Dhar, A. K. Jana, B. K. Behera
Summary: Temperature plays a role in the susceptibility of freshwater fishes to parasitic infections, such as Ichthyophthirius multifiliis, which causes white spot disease. In this study, the researchers investigated the mechanism of co-infection between the parasite and the bacteria Aeromonas hydrophila in Pangasianodon hypophthalmus. They found that supplementation with turmeric oil improved the fish's immune response and increased survival against co-infection. The use of turmeric oil in aquaculture may be a promising strategy to control co-infections in fishes.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Microbiology
Ze-Yi Cao, Bing-Wen Xi, Qing-Jie Zhou, Kai Chen, Jun Xie
Summary: White spot disease, caused by the parasitic ciliate Ichthyophthirius multifiliis, is a significant threat to the freshwater fish farming industry worldwide. The presence of zooplankton, specifically cyclopoid copepods, in the culture water body can significantly reduce the infection of I. multifiliis in goldfish. This study suggests that cyclopoid copepods have the potential to be used as biological control agents against white spot disease in aquaculture.
Article
Environmental Sciences
Ning Ding, Lin Jiang, Xiao Wang, Chun Wang, Yue Geng, Jianxin Zhang, Yingxue Sun, Yanping Zhang, Quan Yuan, Hong Liu
Summary: This study assessed the toxicity of microplastic exposure using zebrafish. Results showed that microplastics can negatively affect the growth rate and intestinal enzyme activities of zebrafish. However, under the tested conditions, concurrent exposure to microplastics and bacteria did not significantly increase zebrafish mortality.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Microbiology
Ke Huang, Guangran Hu, Runqiu Wang, Qingwen Zeng, Wenxiang Li, Hong Zou, Shangong Wu, Guitang Wang, Ming Li
Summary: Berberine has strong toxic effects on the theronts of I. multifiliis, but has no effect on the protomonts. It can reduce the release of theronts and change the shape of protomonts. Berberine could be an effective and safe potential parasiticide for killing I. multifiliis.
Article
Fisheries
Hao Yang, Xiaoting Feng, Xiao Tu, Fangyuan Liu, Ruixue Hu, Zemao Gu
Summary: Epizootic ulcerative syndrome (EUS) is an emerging disease that causes high morbidity and mortality in yellow catfish. The causative agent for EUS in T. fulvifraco is not fully determined. An epidemiological investigation in Hubei province, China, revealed that EUS outbreaks mainly occur in March and April when the water temperature ranges from 13°C to 20°C. Diseased T. fulvifraco exhibit circular-hole shaped ulcers on the skin, and ciliate infections are commonly associated with early EUS. Further diagnoses showed that ciliated parasites, Ichthyophthirius multifiliis and Epistylis horizontalis, heavily infected the specimens, causing severe damages on the skin and gills. In contrast, bacterial infection with Aeromonas versonii was found in only 12.5% of the specimens. These findings suggest that ciliated parasites are the primary agents for early EUS in T. fulvifraco.
Article
Biochemical Research Methods
Yuqin Gou, Fangyuan Zhang, Yueli Tang, Chunxue Jiang, Ge Bai, He Xie, Min Chen, Zhihua Liao
Summary: In this study, nootkatone was successfully synthesized in Artemisia annua using synthetic biology methods, with significantly higher yield in engineered plastids compared to cytosol. This research provides a green approach for producing nootkatone in Artemisia annua with great market potential.
ACS SYNTHETIC BIOLOGY
(2021)
Article
Fisheries
Koumei Shiota, Masaki Sukeda, Harsha Prakash, Masakazu Kondo, Teruyuki Nakanishi, Takahiro Nagasawa, Miki Nakao, Tomonori Somamoto
Summary: This study investigates local immune responses to Ichthyophthirius multifiliis using intra-fin administration in freshwater teleosts. The results suggest that the parasite antigens inhibit macrophages and neutrophils migration, while T-cells are the primary responders. Further research should focus on exploring inhibitory factors of the parasite or examining innate functions of teleost T-cells.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Mateen Nawaz, Moussa Gouife, Songwei Zhu, Xinyuan Yue, Kejing Huang, Rongrong Ma, Jianhu Jiang, Shan Jin, Junquan Zhu, Jiasong Xie
Summary: Goldfish have been used as a model organism to study the immune system and host-pathogen interactions. A bacterium called Aeromonas hydrophila has been causing mass mortality in fish species. This study observed damages in the head kidney of goldfish infected with A. hydrophila and analyzed the gene expression and enzyme activities related to the immune response. The findings will contribute to a better understanding of the early immune response in goldfish and aid in future research on prevention strategies.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Azmi Al-Jubury, Fei Yin, Taghrid Abusharkh, Mehedi Hasan Fuad, Per Walter Kania, Kurt Buchmann
Summary: This study found that brass and its pure constituents (copper and zinc) have in vivo and in vitro antiparasitic effects on freshwater parasites. The results showed that brass and pure copper had a 100% mortality rate on parasites within 15 minutes, while zinc had a 100% mortality rate within 30 minutes. The study also found that direct contact with the metal sheets increased the parasiticidal effect. However, further research is needed to investigate the environmental and ecological effects of metal sheet use.
Article
Fisheries
Aldo Aparecido Proietti-Junior, Luciana Sampaio Lima, Emily Moraes Roges, Yan Correa Rodrigues, Karla Valeria Batista Lima, Dalia Prazeres Rodrigues, Marcos Tavares-Dias
Summary: This study reported an outbreak of disease in pirarucu caused by Aeromonas, conducted experimental co-infection research, and characterized resistance profile, virulence factors, and phenotypic and molecular differentiation. The findings support the existence of synergism between A. hydrophila and A. jandaei in pirarucu, with implications for occurrences of this co-infection and determinants of virulence.
AQUACULTURE RESEARCH
(2021)
Article
Immunology
Zelin Zhao, Hong Wang, Dongxing Zhang, Yongchao Guan, Shahrood Ahmad Siddiqui, Xiao Feng-Shan, Bo Cong
Summary: In this study, the immunogenicity of a recombinant vaccine against A. hydrophila infection in common carps was investigated. The recombinant vaccines showed high efficacy in stimulating immune response and increasing survival rates in the immunized fish.
Article
Biotechnology & Applied Microbiology
Xueqing Fu, Fangyuan Zhang, Yanan Ma, Danial Hassani, Bowen Peng, Qifang Pan, Yuhua Zhang, Zhongxiang Deng, Wenbo Liu, Jixiu Zhang, Lei Han, Dongfang Chen, Jingya Zhao, Ling Li, Xiaofen Sun, Kexuan Tang
Summary: Terpenes are the largest class of secondary metabolites in plants, playing essential roles in plant growth and development as well as having economic value. Through engineering experiments, it has been found that plants can efficiently produce high-value terpenes through photosynthesis at a low cost.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Jiao Li, Xiao-Hui Chu, Xiao-Yu Wang, Bao-Min Feng, Zong-Xia Yu
Summary: Research shows that as the plant ages, artemisinin (ART) gradually accumulates in the leaves of Artemisia annua. Analysis at the sRNA and transcriptome levels indicates that age plays a significant regulatory role in the biosynthesis of ART.
SCIENTIFIC REPORTS
(2021)
Article
Fisheries
Chen Zhang, Sheng Guo, Guo Chen, Zhao Zhao, Gao-Xue Wang, Bin Zhu
Summary: The study developed a novel biomimetic nanovaccine encapsulating a DNA vaccine within a polymer and fish erythrocyte membrane, which efficiently induced local and systemic immune responses in carp via the branchial route.
Article
Fisheries
Kaige Song, Fei Luo, Weichao Chen, Xiaozhou Qi, Yufeng Shen, Jiwei Zha, Fei Ling, Gaoxue Wang
Summary: The ethyl acetate extract from Bacillus velezensis JW supernatant (EJW) showed highly efficient anti-SVCV activity both in vitro and in vivo, inhibiting early events of SVCV replication and increasing the survival rate of infected common carp. Furthermore, EJW up-regulated the expression of antiviral immune genes, indicating its potential as a promising antiviral strategy against SVCV.
Article
Fisheries
Shen-Ye Qu, Xiao-Ping Tan, Bing-Ke Li, Jie-Tao Liu, Gao-Xue Wang, Fei Ling
Summary: This study reports the first record of Ichthyophthirius multifiliis infection in Micropterus salmoides. Malformed fish suffer from more serious Ichthyophthiriasis compared to normal fish. Weak immune response and more tissue damage in malformed fish increase susceptibility to pathogens.
Article
Fisheries
Zhao Zhang, Haibo Cui, Zhiqiang Zhang, Shenye Qu, Gaoxue Wang, Fei Ling
Summary: The study investigated the pharmacokinetics of magnolol in goldfish following different administration routes and found that oral administration of magnolol effectively controlled Ichthyophthirius multifiliis infection. The results indicated that magnolol could be a potential treatment for fish infections caused by I. multifiliis.
Article
Fisheries
Song Zhu, Bo Miao, Yu-Zhou Zhang, De-Shou Wang, Gao-Xue Wang
Summary: Outbreaks of viral encephalopathy and retinopathy severely devastate aquaculture worldwide, with nervous necrosis virus (NNV) being the causative agent. Research suggests that amantadine may be a promising therapeutic agent against NNV, providing an effective strategy for controlling VER in fish at early developmental stages.
JOURNAL OF FISH DISEASES
(2022)
Article
Engineering, Environmental
Kaige Song, Hui Wang, Zhi Jiao, Guangzhou Qu, Weichao Chen, Gaoxue Wang, Tiecheng Wang, Zengqiang Zhang, Fei Ling
Summary: The study demonstrated that pulsed corona discharge plasma (PCDP) can effectively inactivate waterborne viruses, such as SVCV, by damaging their genome and structural proteins. The research also showed that the inactivation efficiency was significantly improved by high input energy density caused by voltage. This has implications for waterborne virus removal and the development of novel disinfection technologies.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Fisheries
Hai-Feng Jiang, Cheng Chen, Xin-Yuan Jiang, Jing-Lei Shen, Fei Ling, Peng-Fei Li, Gao-Xue Wang
Summary: In this study, the efficacy of 12 herbal medicines in inhibiting the proliferation of White Spot Syndrome Virus (WSSV) was evaluated. Lonicera japonica extract was found to have the strongest inhibitory effect, and luteolin (LUT) was identified as the major bioactive compound. LUT showed a strong inhibitory effect on WSSV replication, decreased viral load, and increased the survival rate of WSSV-infected crayfish. It also modulated the expression of immunerelated genes, antioxidants, proinflammatory factors, and apoptosis-related genes.
Article
Fisheries
Bo-Yang Li, Fei Yang, Zhong-Yu Zhang, Yu-Feng Shen, Tao Wang, Liang Zhao, Jia-Cheng Qin, Fei Ling, Gao-Xue Wang
Summary: In this study, the antiviral effects of 22 quinoline derivatives against Micropterus salmoides rhabdovirus (MSRV) were evaluated. 8-hydroxyquinoline was found to effectively inhibit MSRV in vitro and enhance survival rates in MSRV-infected fish in vivo. It also reduced viral loads in the infected fish.
JOURNAL OF FISH DISEASES
(2022)
Article
Parasitology
Zhen Yang, Xiaoping Tan, Zhiqiang Zhang, Jing Han, Shenye Qu, Tianqiang Liu, Gaoxue Wang
Summary: In this study, ononin, isolated from Spatholobi caulis, was found to have potent parasiticidal activity against Dactylogyrus. The compound showed a low EC50 value and 100% activity against the parasiticide, indicating its potential as a new anti-parasitic drug for the control of Dactylogyrus.
PARASITOLOGY INTERNATIONAL
(2022)
Article
Environmental Sciences
Gengrong Zhang, Linhan Li, Guoqing Zhou, Zhiyang Lin, Jun Wang, Gaoxue Wang, Fei Ling, Tianqiang Liu
Summary: A novel super adsorbent, boronic acid-modified bacterial cellulose microspheres, showed great potential in the removal of tetracycline from water, with high adsorption capacity, a simple preparation process, and excellent recovery performance.
ENVIRONMENTAL POLLUTION
(2022)
Article
Fisheries
Xin-Yuan Jiang, Zong-Yi Ren, Nian-Kun Zhang, Ke-Chen Yang, Gao-Xue Wang, Hai-Feng Jiang
Summary: This study identified honokiol from Magnolia officinalis as a potent antibacterial compound against Nocardia seriolae, suggesting its potential as a therapeutic agent for controlling nocardiosis in aquaculture.
JOURNAL OF FISH DISEASES
(2022)