Transgenesis in Strongyloides and related parasitic nematodes: historical perspectives, current functional genomic applications and progress towards gene disruption and editing

The genomic basis of parasitism in the Strongyloides clade of nematodes

(2016) Vicky L Hunt et al.   NATURE GENETICS

A split-Cas9 architecture for inducible genome editing and transcription modulation

(2015) Bernd Zetsche et al.   NATURE BIOTECHNOLOGY

The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations

(2015) V. M. Gantz et al.   SCIENCE

Knocking down schistosomes – promise for lentiviral transduction in parasites

(2015) Jana Hagen et al.   TRENDS IN PARASITOLOGY

Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus

(2014) Hanh Witte et al.   DEVELOPMENT GENES AND EVOLUTION

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

Exciting Prospects for Precise Engineering of Caenorhabditis elegans Genomes with CRISPR/Cas9

(2013) Christian Frøkjær-Jensen   GENETICS

Precise and Heritable Genome Editing in Evolutionarily Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions

(2013) T.-W. Lo et al.   GENETICS

CRISPR/Cas9-Targeted Mutagenesis in Caenorhabditis elegans

(2013) Selma Waaijers et al.   GENETICS

Heritable Gene Knockout in Caenorhabditis elegans by Direct Injection of Cas9–sgRNA Ribonucleoproteins

(2013) Seung Woo Cho et al.   GENETICS

Strongyloides stercoralis daf-2 encodes a divergent ortholog of Caenorhabditis elegans DAF-2

(2013) Holman C. Massey et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The dauer hypothesis and the evolution of parasitism: 20years on and still going strong

(2013) Matt Crook   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Heritable genome editing in C. elegans via a CRISPR-Cas9 system

(2013) Ari E Friedland et al.   NATURE METHODS

The CRISPR Craze

(2013) E. Pennisi   SCIENCE

Improved Mos1-mediated transgenesis in C. elegans

(2012) Christian Frøkjær-Jensen et al.   NATURE METHODS

Characterization of genes with a putative key role in the parasitic lifestyle of the nematode Strongyloides ratti

(2012) W. G. SPINNER et al.   PARASITOLOGY

Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites

(2011) Jannik Fonager et al.   BMC GENOMICS

Ups and downs of RNA interference in parasitic nematodes

(2011) Collette Britton et al.   EXPERIMENTAL PARASITOLOGY

Transgenesis in the parasitic nematode Strongyloides ratti

(2011) Xinshe Li et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Nucleic acid transfection and transgenesis in parasitic nematodes

(2011) JAMES B. LOK   PARASITOLOGY

Paving the way for transgenic schistosomes

(2011) S. BECKMANN et al.   PARASITOLOGY

Asparagine repeat function in a Plasmodium falciparum protein assessed via a regulatable fluorescent affinity tag

(2011) V. Muralidharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retroviral and Transposon-Based Tet-Regulated All-In-One Vectors with Reduced Background Expression and Improved Dynamic Range

(2010) Niels Heinz et al.   HUMAN GENE THERAPY

Response of the Strongyloides ratti transcriptome to host immunological environment

(2010) Helen O’Meara et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

In vivo transfection of developmentally competent Brugia malayi infective larvae

(2010) Shulin Xu et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation

(2010) Takamasa Ishii et al.   MITOCHONDRION

Transduction of Schistosoma japonicum schistosomules with vesicular stomatitis virus glycoprotein pseudotyped murine leukemia retrovirus and expression of reporter human telomerase reverse transcriptase in the transgenic schistosomes

(2010) Shenghui Yang et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A new DAF-16 isoform regulates longevity

(2010) Eun-Soo Kwon et al.   NATURE

RIOK3 interacts with caspase-10 and negatively regulates the NF-κB signaling pathway

(2009) Jingxuan Shan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Morphogenesis of Strongyloides stercoralis Infective Larvae Requires the DAF-16 Ortholog FKTF-1

(2009) Michelle L. Castelletto et al.   PLoS Pathogens

Transcript profiles of long- and short-lived adults implicate protein synthesis in evolved differences in ageing in the nematode Strongyloides ratti

(2008) Fiona J. Thompson et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Single-copy insertion of transgenes in Caenorhabditis elegans

(2008) Christian Frøkjær-Jensen et al.   NATURE GENETICS

Tv-RIO1 – an atypical protein kinase from the parasitic nematode Trichostrongylus vitrinus

(2008) Min Hu et al.   Parasites & Vectors

Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer

(2008) A. C. Kimmelman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strongyloides stercoralis: Cell- and tissue-specific transgene expression and co-transformation with vector constructs incorporating a common multifunctional 3′ UTR

(2007) Ariel B. Junio et al.   EXPERIMENTAL PARASITOLOGY

Genes important in the parasitic life of the nematode Strongyloides ratti

(2007) Fiona J. Thompson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY