The trypanosome alternative oxidase: a potential drug target?

Exploiting the Achilles’ heel of membrane trafficking in trypanosomes

(2016) Martin Zoltner et al.   CURRENT OPINION IN MICROBIOLOGY

Unraveling the Heater: New Insights into the Structure of the Alternative Oxidase

(2013) Anthony L. Moore et al.   Annual Review of Plant Biology

Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues

(2013) Xu-Wen Li et al.   Beilstein Journal of Organic Chemistry

Structure of the trypanosome cyanide-insensitive alternative oxidase

(2013) T. Shiba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story

(2013) Nicola Baker et al.   TRENDS IN PARASITOLOGY

Management of trypanosomiasis and leishmaniasis

(2012) M. P. Barrett et al.   BRITISH MEDICAL BULLETIN

Pharmacophore identification of ascofuranone, potent inhibitor of cyanide-insensitive alternative oxidase of Trypanosoma brucei

(2012) Hiroyuki Saimoto et al.   JOURNAL OF BIOCHEMISTRY

Estimating and Mapping the Population at Risk of Sleeping Sickness

(2012) Pere P. Simarro et al.   PLoS Neglected Tropical Diseases

Multiple roles of proline transport and metabolism in trypanosomatids

(2011) Frederic Bringaud   Frontiers in Bioscience-Landmark

Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidase fromTrypanosoma brucei brucei

(2010) Yasutoshi Kido et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies

(2010) Kosuke Nakamura et al.   PARASITOLOGY INTERNATIONAL

Three Redox States ofTrypanosoma bruceiAlternative Oxidase Identified by Infrared Spectroscopy and Electrochemistry

(2009) Amandine Maréchal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compelling EPR evidence that the alternative oxidase is a diiron carboxylate protein

(2008) Anthony L. Moore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Antibiotics LL-Z1272 identified as novel inhibitors discriminating bacterial and mitochondrial quinol oxidases

(2008) Tatsushi Mogi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS