The Plasmodium falciparum chloroquine resistance transporter is associated with the ex vivo P. falciparum African parasite response to pyronaridine

Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment

(2015) Rithea Leang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study

(2015) Michele D Spring et al.   LANCET INFECTIOUS DISEASES

Multinormal in vitro distribution of Plasmodium falciparum susceptibility to piperaquine and pyronaridine

(2015) Aurélie Pascual et al.   MALARIA JOURNAL

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence for Pyronaridine as a Highly Effective Partner Drug for Treatment of Artemisinin-Resistant Malaria in a Rodent Model

(2013) Philipp P. Henrich et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Repeat Polymorphisms in the Low-Complexity Regions of Plasmodium falciparum ABC Transporters and Associations withIn VitroAntimalarial Responses

(2013) John Okombo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroSensitivities of Plasmodium falciparum Isolates from the China-Myanmar Border to Piperaquine and Association with Polymorphisms in Candidate Genes

(2013) Mingming Hao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro piperaquine susceptibility is not associated with the Plasmodium falciparum chloroquine resistance transporter gene

(2013) Aurélie Pascual et al.   MALARIA JOURNAL

Pyronaridine-artesunate granules versus artemether-lumefantrine crushed tablets in children with Plasmodium falciparum malaria: a randomized controlled trial

(2012) Kassoum Kayentao et al.   MALARIA JOURNAL

Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum

(2012) Aurélie Pascual et al.   MALARIA JOURNAL

Review of pyronaridine anti-malarial properties and product characteristics

(2012) Simon L Croft et al.   MALARIA JOURNAL

Pyronaridine–Artesunate versus Mefloquine plus Artesunate for Malaria

(2012) Ronnatrai Rueangweerayut et al.   NEW ENGLAND JOURNAL OF MEDICINE

BaselineIn VitroActivities of the Antimalarials Pyronaridine and Methylene Blue against Plasmodium falciparum Isolates from Kenya

(2011) John Okombo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pyronaridine-Artesunate versus Chloroquine in Patients with Acute Plasmodium vivax Malaria: A Randomized, Double-Blind, Non-Inferiority Trial

(2011) Yi Poravuth et al.   PLoS One

Absence of Association between Piperaquine In Vitro Responses and Polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe Genes in Plasmodium falciparum

(2010) S. Briolant et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of Pyronaridine against Multidrug-Resistant Plasmodium falciparum and Plasmodium vivax

(2010) R. N. Price et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial

(2010) Antoinette K Tshefu et al.   LANCET

Absence of association between pyronaridine in vitro responses and polymorphisms in genes involved in quinoline resistance in Plasmodium falciparum

(2010) Bruno Pradines et al.   MALARIA JOURNAL

In Vitro Activities of Piperaquine, Lumefantrine, and Dihydroartemisinin in Kenyan Plasmodium falciparum Isolates and Polymorphisms in pfcrt and pfmdr1

(2009) L. Mwai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE