The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models

The use of a TLR2 agonist-based adjuvant for enhancing effector and memory CD8 T-cell responses

(2014) Brendon Y Chua et al.   IMMUNOLOGY AND CELL BIOLOGY

Pegylated Bisacycloxypropylcysteine, a Diacylated Lipopeptide Ligand of TLR6, Plays a Host-Protective Role against ExperimentalLeishmania majorInfection

(2014) Surya Prakash Pandey et al.   JOURNAL OF IMMUNOLOGY

Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

(2014) C. Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial lipid modification enhances immunoprophylaxis of filarial abundant larval transcript-2 protein inMastomysmodel

(2013) S. Sharmila et al.   PARASITE IMMUNOLOGY

Mechanisms of Action of Adjuvants

(2013) Sunita Awate et al.   Frontiers in Immunology

Immunostimulation by Synthetic Lipopeptide-Based Vaccine Candidates: Structure-Activity Relationships

(2013) Mehfuz Zaman et al.   Frontiers in Immunology

Evaluation of Recombinant Leishmania Polyprotein Plus Glucopyranosyl Lipid A Stable Emulsion Vaccines against Sand Fly-Transmitted Leishmania major in C57BL/6 Mice

(2012) N. C. Peters et al.   JOURNAL OF IMMUNOLOGY

Adjuvants for Leishmania vaccines: from models to clinical application

(2012) Vanitha S. Raman et al.   Frontiers in Immunology

Antigen depot is not required for alum adjuvanticity

(2011) Sharon Hutchison et al.   FASEB JOURNAL

Promiscuous Peptide of 16 kDa Antigen Linked to Pam2Cys Protects Against Mycobacterium tuberculosis by Evoking Enduring Memory T-Cell Response

(2011) Uthaman Gowthaman et al.   JOURNAL OF INFECTIOUS DISEASES

Immunological mechanisms of vaccination

(2011) Bali Pulendran et al.   NATURE IMMUNOLOGY

Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity

(2011) Tracy L Flach et al.   NATURE MEDICINE

Future prospects and challenges of vaccines against filariasis

(2011) S. A. BABAYAN et al.   PARASITE IMMUNOLOGY

TLR2-Dependent Induction of IL-10 and Foxp3+CD25+CD4+ Regulatory T Cells Prevents Effective Anti-Tumor Immunity Induced by Pam2 Lipopeptides In Vivo

(2011) Sayuri Yamazaki et al.   PLoS One

TLR1/2 Activation during Heterologous Prime-Boost Vaccination (DNA-MVA) Enhances CD8+ T Cell Responses Providing Protection against Leishmania (Viannia)

(2011) Asha Jayakumar et al.   PLoS Neglected Tropical Diseases

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

Use of defined TLR ligands as adjuvants within human vaccines

(2010) Malcolm S. Duthie et al.   IMMUNOLOGICAL REVIEWS

Using an intravenous catheter to carry out abdominal lavage in the gerbil

(2010) Kathryn G. Griffiths et al.   LAB ANIMAL

Repeated inoculation of killed Leishmania major induces durable immune response that protects mice against virulent challenge

(2010) Ifeoma Okwor et al.   VACCINE

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with sodium stibogluconate for the treatment of mucosal leishmaniasis

(2010) Alejandro Llanos-Cuentas et al.   VACCINE

Distinct Roles for MyD88 and Toll-Like Receptor 2 during Leishmania braziliensis Infection in Mice

(2009) D. A. Vargas-Inchaustegui et al.   INFECTION AND IMMUNITY

WolbachiaLipoprotein Stimulates Innate and Adaptive Immunity through Toll-like Receptors 2 and 6 to Induce Disease Manifestations of Filariasis

(2009) Joseph D. Turner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity

(2009) A. M. Didierlaurent et al.   JOURNAL OF IMMUNOLOGY

The involvement of TLR2 in cytokine and reactive oxygen species (ROS) production by PBMCs in response to Leishmania major phosphoglycans (PGs)

(2009) G. KAVOOSI et al.   PARASITOLOGY

Self-Adjuvanting Lipopeptide Vaccines

(2008) Peter Moyle et al.   CURRENT MEDICINAL CHEMISTRY

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

(2008) Stephanie C. Eisenbarth et al.   NATURE