Increased expression of ATP binding cassette transporter genes following exposure of Haemonchus contortus larvae to a high concentration of monepantel in vitro

Larval development assays reveal the presence of sub-populations showing high- and low-level resistance in a monepantel (Zolvix®)-resistant isolate of Haemonchus contortus

(2016) Ali Raza et al.   VETERINARY PARASITOLOGY

Effects of in vitro exposure to ivermectin and levamisole on the expression patterns of ABC transporters in Haemonchus contortus larvae

(2016) Ali Raza et al.   International Journal for Parasitology-Drugs and Drug Resistance

Haemonchus contortus P-glycoprotein-2: in situ localisation and characterisation of macrocyclic lactone transport

(2015) Pablo Godoy et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Integrated assessment of ivermectin pharmacokinetics, efficacy against resistant Haemonchus contortus and P-glycoprotein expression in lambs treated at three different dosage levels

(2015) Luis Alvarez et al.   VETERINARY PARASITOLOGY

Haemonchus contortus resistance to monepantel in sheep

(2015) R. Van den Brom et al.   VETERINARY PARASITOLOGY

Gene expression of ABC transporters in Cooperia oncophora after field and laboratory selection with macrocyclic lactones

(2015) Eva Tydén et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

First report of monepantel Haemonchus contortus resistance on sheep farms in Uruguay

(2014) América E Mederos et al.   Parasites & Vectors

Monepantel: the most studied new anthelmintic drug of recent years

(2014)   PARASITOLOGY

P-gp modulating drugs greatly potentiate the in vitro effect of ivermectin against resistant larvae of Haemonchus placei

(2014) R.P. Heckler et al.   VETERINARY PARASITOLOGY

Accumulation of monepantel and its sulphone derivative in tissues of nematode location in sheep: Pharmacokinetic support to its excellent nematodicidal activity

(2014) A. Lifschitz et al.   VETERINARY PARASITOLOGY

Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions

(2014) Andrew C. Kotze et al.   International Journal for Parasitology-Drugs and Drug Resistance

Resistance to the macrocyclic lactone moxidectin is mediated in part by membrane transporter P-glycoproteins: Implications for control of drug resistant parasitic nematodes

(2014) Elizabeth E. Bygarski et al.   International Journal for Parasitology-Drugs and Drug Resistance

Gene expression analysis of ABC transporters in a resistant Cooperia oncophora isolate following in vivo and in vitro exposure to macrocyclic lactones

(2013) J. DE GRAEF et al.   PARASITOLOGY

PGP expression in Cooperia oncophora before and after ivermectin selection

(2013) Marlene Areskog et al.   PARASITOLOGY RESEARCH

Lack of efficacy of monepantel against Teladorsagia circumcincta and Trichostrongylus colubriformis

(2013) I. Scott et al.   VETERINARY PARASITOLOGY

Inhibition of P-glycoprotein enhances sensitivity of Caenorhabditis elegans to ivermectin

(2012) Bernadette F. Ardelli et al.   VETERINARY PARASITOLOGY

Relative Neurotoxicity of Ivermectin and Moxidectin in Mdr1ab (−/−) Mice and Effects on Mammalian GABA(A) Channel Activity

(2012) Cécile Ménez et al.   PLoS Neglected Tropical Diseases

Comparative tissue pharmacokinetics and efficacy of moxidectin, abamectin and ivermectin in lambs infected with resistant nematodes: Impact of drug treatments on parasite P-glycoprotein expression

(2012) Mercedes Lloberas et al.   International Journal for Parasitology-Drugs and Drug Resistance

Gene expression changes in a P-glycoprotein (Tci-pgp-9) putatively associated with ivermectin resistance in Teladorsagia circumcincta

(2011) Alison J. Dicker et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance

(2011) Anne Lespine et al.   International Journal for Parasitology-Drugs and Drug Resistance

Haemonchus contortus Acetylcholine Receptors of the DEG-3 Subfamily and Their Role in Sensitivity to Monepantel

(2009) Lucien Rufener et al.   PLoS Pathogens

Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans

(2008) Catherine E. James et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A new class of anthelmintics effective against drug-resistant nematodes

(2008) Ronald Kaminsky et al.   NATURE