Exploratory Study on the RNA-Binding Structural Motifs by Library Screening Targeting pre-miRNA-29 a

Hepatitis C Virus RNA Functionally Sequesters miR-122

(2015) Joseph M. Luna et al.   CELL

miR-122 – A key factor and therapeutic target in liver disease

(2015) Simonetta Bandiera et al.   JOURNAL OF HEPATOLOGY

Synthesis of 8-Substituted Adenine and Adenosine Libraries and the Binding to pre-miR-29a

(2014) Takeo Fukuzumi et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Sequence-based design of bioactive small molecules that target precursor microRNAs

(2014) Sai Pradeep Velagapudi et al.   Nature Chemical Biology

Association of a peptoid ligand with the apical loop of pri-miR-21 inhibits cleavage by Drosha

(2014) J. P. Diaz et al.   RNA

Perspectives in targeting miRNA function

(2013) Christiane Schöniger et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fluorescent indicator displacement assay of ligands targeting 10 microRNA precursors

(2013) Asako Murata et al.   BIOORGANIC & MEDICINAL CHEMISTRY

MiRNA-29: A microRNA Family with Tumor-Suppressing and Immune-Modulating Properties

(2013) M.J. Schmitt et al.   CURRENT MOLECULAR MEDICINE

The role of miRNA-29 family in cancer

(2013) Yang Wang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122

(2013) Luca F. R. Gebert et al.   NUCLEIC ACIDS RESEARCH

Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules

(2012) Asako Murata et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure-Activity Studies on the Fluorescent Indicator in a Displacement Assay for the Screening of Small Molecules Binding to RNA

(2012) Shiori Umemoto et al.   CHEMISTRY-A EUROPEAN JOURNAL

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

(2012) Wei-Chih Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex

(2012) T. Shimakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent Advances in Developing Small Molecules Targeting RNA

(2011) Lirui Guan et al.   ACS Chemical Biology

The Tuberculosis Drug Streptomycin as a Potential Cancer Therapeutic: Inhibition of miR-21 Function by Directly Targeting Its Precursor

(2011) Debojit Bose et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing

(2011) Mohitosh Maiti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance

(2011) Andreas Karakatsanis et al.   MOLECULAR CARCINOGENESIS

Evolution of microRNA diversity and regulation in animals

(2011) Eugene Berezikov   NATURE REVIEWS GENETICS

A modified fluorescent intercalator displacement assay for RNA ligand discovery

(2010) Papa Nii Asare-Okai et al.   ANALYTICAL BIOCHEMISTRY

Fluorescent Indicator Displacement Assay for Ligand−RNA Interactions

(2010) Jinhua Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma

(2010) Douglas D. Young et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Plasma MicroRNAs as Sensitive and Specific Biomarkers of Tissue Injury

(2009) O. F. Laterza et al.   CLINICAL CHEMISTRY

miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis

(2009) Christoph A Gebeshuber et al.   EMBO REPORTS

MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines

(2009) M.K. Muniyappa et al.   EUROPEAN JOURNAL OF CANCER

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

Discovering ligands for a microRNA precursor with peptoid microarrays

(2009) Sara Chirayil et al.   NUCLEIC ACIDS RESEARCH

Ligands playing musical chairs with G-quadruplex DNA: A rapid and simple displacement assay for identifying selective G-quadruplex binders

(2008) D. Monchaud et al.   BIOCHIMIE

Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay

(2008) Malathy Krishnamurthy et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Targeting RNA with Small Molecules

(2008) Jason R. Thomas et al.   CHEMICAL REVIEWS

Messenger RNA regulation: to translate or to degrade

(2008) Ann-Bin Shyu et al.   EMBO JOURNAL

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

(2008) S. S. Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication

(2008) Jasmine K Ahluwalia et al.   Retrovirology