Article
Gastroenterology & Hepatology
Monique T. Barakat, Swarnadip Ghosh, Subhas Banerjee
Summary: The study assessed various approaches to minimize infection transmission costs and found that partially disposable duodenoscopes were the most favorable option from a cost utility standpoint. Fully disposable duodenoscopes minimized the potential for infection transmission and were more cost-effective than reprocessable duodenoscopes after single or double high-level disinfection, ethylene oxide sterilization, and culture and hold.
GASTROINTESTINAL ENDOSCOPY
(2022)
Article
Engineering, Environmental
Eduardo de Paula Nascente, Ursula Nunes Rauecker, Amanda Vargas Teles, Lorena Dias do Amor Divino, Sarah Rodrigues Chagas, Luan Mendes Elias, Moema Pacheco Chediak Matos, Maria Auxiliadora Andrade, Livia Mendonca Pascoal
Summary: The study found that ozonated water could effectively inhibit the growth of Salmonella Heidelberg and alter its DNA concentration, showing certain effectiveness in suppressing the bacteria.
OZONE-SCIENCE & ENGINEERING
(2022)
Article
Gastroenterology & Hepatology
Sathvik Namburar, Daniel von Renteln, John Damianos, Lisa Bradish, Jeanne Barrett, Andres Aguilera-Fish, Benoit Cushman-Roisin, Heiko Pohl
Summary: Specialties like surgery and endoscopy contribute significantly to the environmental impact of the healthcare sector. A study in the USA found that a large amount of waste is generated from endoscopic procedures, with 64% ending up in landfills. Transitioning to single-use endoscopes could reduce reprocessing waste but increase overall waste production.
Review
Biotechnology & Applied Microbiology
Micha Peleg
Summary: Giardia cysts in lake waters continue to die off even after being exposed to short sublethal ozonation. The delayed inactivation of the cysts can be described by a modified microbial survival model adapted for injured cysts. The downward concavity of the cysts' survival ratio suggests a unimodal temporal distribution of deaths.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Gastroenterology & Hepatology
Simone Vieira Toledo Guadagnin, Dayane de Melo Costa, Mariusa Gomes Borges Primo, Adriana Azevedo Silva, Lara Stefania Netto de Oliveira Leao-Vasconcelos, Karen Vickery, Anaclara Ferreira Veiga Tipple
Summary: This study aimed to determine bacterial contamination in flexible gastroscopes channels after storage in a cabinet without forced-air drying. The results showed that bacterial contamination increased with longer storage time.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Oncology
Samar Al-Saleh, Abdullah Alshahrani, Ahmed Heji Albaqawi, Firas K. Alqarawi, Khaled M. Alzahrani, Syeda Abeerah Tanveer, Saim Siddiqui, Mustafa Naseem, Fahim Vohra, Tariq Abduljabbar
Summary: The study evaluated the effectiveness of chemical, ultrasonic, and photodynamic therapy (PDT) mediated disinfection on biofilms colonized with three different strains on PMMA denture base material. The results showed that ultrasonic disinfection was most effective in reducing viable microbial counts, while PDT mediated by Rose Bengal showed a more substantial reduction of S. aureus colonies.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2022)
Article
Environmental Sciences
Siqi Liu, Jaeshin Kim, Gregory V. Korshin
Summary: This study compared the effects of conventional ozonation and electrochemical oxidation on the formation of aldehydes and aliphatic carboxylic acids during the oxidation of natural organic matter in low-mineralized surface water. The results showed that both ozonation and electrochemical oxidation were effective in degrading the organic matter, but ozonation resulted in higher yields of aldehydes while electrochemical oxidation produced fewer aliphatic carboxylic acids. Furthermore, the presence of elevated carbonate concentration had a minor influence on disinfection by-products in electrochemical oxidation.
Article
Engineering, Environmental
Maycon Crispim de Oliveira Carvalho, Adriana Barrinha Fernandes, Henrique Cunha Carvalho, Renato Amaro Zangaro, Carlos Jose de Lima
Summary: This study aimed to develop a fluid-dynamic system with ozonated water to achieve high-level disinfection for endoscopes. A colonoscope replica was contaminated, washed, and disinfected with ozonated water in a tank with a fluid-dynamic circuit. Quantitative microbiological tests were conducted in the fluid-dynamic system, and the results showed that the system effectively achieved high-level disinfection of the colonoscope.
OZONE-SCIENCE & ENGINEERING
(2023)
Article
Public, Environmental & Occupational Health
Bo Jin, Yue Hu, Liang Huang, Xiaoyun Cheng, Jin Zhao, Xuejing Yang, Xiling Sun, Tieer Gan, Bin Lu
Summary: The study compared the effectiveness of daily and after-each-case room disinfection in an endoscopy unit. Results showed that after-each-case disinfection had lower microbial load on certain items compared to daily disinfection. For high-risk patients, after-each-case disinfection was more suitable, while daily disinfection met basic health requirements for low-risk patients.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Erkan Gonulol, Goksel Tirpanci Sivri, Mehmet Recai Durgut, Ahmet Refik Onal
Summary: The study focuses on the biosecurity of livestock industry, particularly examining foot bathing as a routine control to protect animals from diseases. The experimental work explores the potential benefits of ozonated water systems in the foot bathing process.
FRESENIUS ENVIRONMENTAL BULLETIN
(2021)
Article
Public, Environmental & Occupational Health
Hye Young Shin, Da Hun Jang, Jae Kwan Jun
Summary: The study showed that healthcare professionals who have participated in endoscope reprocessing training are more likely to adhere to the guidelines, and they are generally satisfied with the current training. National training programs can help ensure quality control for endoscopy, but further training is needed for half of the practitioners currently working in endoscopy units.
AMERICAN JOURNAL OF INFECTION CONTROL
(2021)
Article
Otorhinolaryngology
Stefan A. Rudhart, Frank Guenther, Laura Dapper, Kruthika Thangavelu, Urban W. Geisthoff, Petar Stankovic, Thomas Wilhelm, Boris A. Stuck, Stephan Hoch
Summary: The study showed that Impelux (TM) UV-C light technology efficiently reduces bacterial contamination of flexible endoscopes and eliminates protein residuals, providing a potential solution for clinical use.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Yana Halmans, David J. Wellenstein, Michael Romijn, Suzan Cremers, Jannie J. Smit, Joost Hopman, Robert P. Takes, Guido B. van den Broek
Summary: This study compares the reduction in colony-forming units (CFUs) on contaminated flexible endoscopes (FEs) without a working channel after UV-C light disinfection and the current gold standard, the endoscope washer disinfector (EWD). The results show that there is no difference in CFU reduction between UV-C light disinfection and the EWD.
CLINICAL OTOLARYNGOLOGY
(2023)
Article
Microbiology
Anja M. M. Richter, Katharina Konrat, Ane M. M. Osland, Emma Brook, Claire Oastler, Lene K. K. Vestby, Rebecca J. J. Gosling, Live L. L. Nesse, Mardjan Arvand
Summary: Salmonella is a common problem in food and feed products in the European Union and can be transmitted through contaminated surfaces. Biofilms, where bacteria like Salmonella are found, provide protection against antibiotics and disinfectants. The efficacy testing methods for disinfectants against Salmonella biofilms need to be standardized. This study evaluated three models for disinfectant efficacy testing on Salmonella Typhimurium biofilms and found differences in achievable cell numbers, repeatability, and reproducibility of results among the methods. Developing a standardized protocol for testing disinfectant efficacy on biofilms is important for effectively eliminating biofilms.
Article
Plant Sciences
Simona Paulikiene, Renata Zvirdauskiene
Summary: This study investigated the qualitative characteristics of winter wheat treated with ozonated water. The results showed that ozonated water treatment effectively reduced mold fungi in the grains and flour, improving the mycological safety of the flour samples. However, it did not significantly affect the basic composition of the winter wheat grains.
Article
Engineering, Biomedical
Stella Giansante, Hector Enrique Giana, Adriana Barrinha Fernandes, Landulfo Silveira
Summary: The study evaluated the analytical performance of Raman spectroscopy for analyzing lipid profile, non-protein nitrogenous compounds, and glucose in human serum samples. The results demonstrated that Raman spectroscopy can be an important methodology, especially for screening serum triglycerides and cholesterol in the population. The analytical error was within acceptable ranges for most components, showing good potential for future widespread use.
LASERS IN MEDICAL SCIENCE
(2022)
Article
Engineering, Environmental
Vera Lucia Taba, Henrique Cunha Carvalho, Tulia de Souza Botelho, Adriana Barrinha Fernandes, Carlos Jose de Lima, Antonio Balbin Villaverde
Summary: Ethylene oxide and gamma irradiation are commonly used sterilizing processes for surgical materials, but they have toxicity and high cost issues. Ozone gas (O-3(g)) has been effectively used for disinfection and sterilization. Low pressure can promote water vaporization and has been found to be effective for sterilizing surgical needles. The study showed that low pressure + O-3(g) and O-3(g) alone had sterilizing effects.
OZONE-SCIENCE & ENGINEERING
(2023)
Article
Engineering, Environmental
Silvia Mobille Awoyama, Henrique Cunha Carvalho, Tulia de Souza Botelho, Sandra Irene Sprogis Dos Santos, Debora Alicia Buendia Palacios, Sebastian San Martin Henrique, Renato Amaro Zangaro, Carlos Jose de Lima, Adriana Barrinha Fernandes
Summary: This study evaluated a hydrodynamic system that uses ozonated water for disinfecting human amniotic membrane (hAM) and assessed possible morphological alterations using histological analysis and scanning electron microscopy (SEM). The results showed that the technique effectively eliminated microorganisms and maintained the structural integrity of hAM during the disinfection process.
OZONE-SCIENCE & ENGINEERING
(2023)
Article
Engineering, Environmental
Livia Helena Moreira, Maria Katiana Salomao, Henrique Cunha Carvalho, Andre Luis Silva Mendes, Ranato Amaro Zangaro, Adriana Barrinha Fernandes, Carlos Jose de Lima
Summary: The study found that exposure to ozonated water for 15 minutes under dynamic conditions impaired the biological viability of peritoneum tissue. However, submitting the biological sample to the dynamic fluid system with ozonated water for 10 minutes at a lower ozone dose did not induce significant changes to the tissue.
OZONE-SCIENCE & ENGINEERING
(2022)
Article
Obstetrics & Gynecology
Maria Veronica Pires, Carlos Jose de Lima, Henrique Cunha Carvalho, Livia Helena Moreira, Adriana Barrinha Fernandes
Summary: This study aimed to investigate the efficacy of intravesical ozone therapy in IC/BPS patients who had not responded to conventional treatment. The results showed that intravesical ozone therapy had a significant therapeutic effect in these patients, with minimal side effects and a low recurrence rate in the short term.
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2023)
Article
Neurosciences
Debora Buendia, Tatiana Guncay, Macarena Oyanedel, Makarena Lemus, Alejandro Weinstein, Alvaro O. Ardiles, Jose Marcos, Adriana Fernandes, Renato Zangaro, Pablo Munoz
Summary: This study evaluated the effects of transcranial light therapy on synaptic plasticity and cognitive functions in an Alzheimer's disease animal model. The results suggest that TLTC may be an effective non-invasive treatment for AD-associated synaptic plasticity deficits.
Article
Engineering, Environmental
Maycon Crispim de Oliveira Carvalho, Adriana Barrinha Fernandes, Henrique Cunha Carvalho, Renato Amaro Zangaro, Carlos Jose de Lima
Summary: This study aimed to develop a fluid-dynamic system with ozonated water to achieve high-level disinfection for endoscopes. A colonoscope replica was contaminated, washed, and disinfected with ozonated water in a tank with a fluid-dynamic circuit. Quantitative microbiological tests were conducted in the fluid-dynamic system, and the results showed that the system effectively achieved high-level disinfection of the colonoscope.
OZONE-SCIENCE & ENGINEERING
(2023)
Review
Cell Biology
Renan Fava Marson, Andrea Pereira Regner, Lindolfo da Silva Meirelles
Summary: Cultured mesenchymal stromal cells have great potential in clinical trials, but their therapeutic benefits have not been fully realized. This review explores the possibility that activated subpopulations of perivascular and/or adventitial cells may behave as MSCs in tissue injury, contributing to the resolution of tissue injury by promoting the development of regenerative macrophages.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Review
Urology & Nephrology
Maria Veronica Pires, Henrique Cunha Carvalho, Livia Helena Moreira, Adriana Barrinha Fernandes, Carlos Jose de Lima
Summary: Despite the limited number of specific studies, recent findings suggest that ozone therapy could be a promising alternative for managing IC/BPS due to its antioxidant, anti-inflammatory, and immunomodulatory effects.
CURRENT BLADDER DYSFUNCTION REPORTS
(2023)
Article
Engineering, Biomedical
Ana Cristina Castro Goulart, Renato Amaro Zangaro, Henrique Cunha Carvalho, Igor K. Lednev, Landulfo Silveira
Summary: This study proposes a technique for diagnosing COVID-19 through nasopharyngeal secretion using Raman spectroscopy, which enables rapid and label-free evaluation. By analyzing the spectral features and establishing a model, COVID-19 samples can be accurately differentiated from control samples.
LASERS IN MEDICAL SCIENCE
(2023)
Article
Biotechnology & Applied Microbiology
Elzo Everton de Sousa Vieira, Landulfo Silveira Jr, Henrique Cunha Carvalho, Jeyse Aliana Martins Bispo, Fernanda Barrinha Fernandes, Adriana Barrinha Fernandes
Summary: This study compared conventional spectrophotometry and Raman spectroscopy for biochemical analysis of urine from healthy and diabetic and hypertensive patients, finding significant differences in glucose peaks. Using principal component analysis, spectral differences between the two groups were identified, and a partial least squares regression model estimated concentrations of multiple metabolites in urine, showing the potential for distinguishing between subjects with diabetes and hypertension from healthy individuals in urinalysis via Raman spectra.
BIOENGINEERING-BASEL
(2022)
Article
Engineering, Biomedical
Joao Pedro Scaldaferri Martins, Carlos Jose de Lima, Adriana Barrinha Fernandes, Leandro Procopio Alves, Osmar Pinto Neto, Antonio Balbin Villaverde
Summary: This study aimed to compare the effectiveness of therapeutic ultrasound combined with LED photobiomodulation therapy in treating shoulder tendinopathy. The results showed that the combination of infrared light and ultrasound (IR-US) was the best treatment for rotator cuff tendinopathy.
LASERS IN MEDICAL SCIENCE
(2022)
