Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates

Pentameric Thiophene-Based Ligands that Spectrally Discriminate Amyloid-β and Tau Aggregates Display Distinct Solvatochromism and Viscosity-Induced Spectral Shifts

(2014) Rozalyn A. Simon et al.   CHEMISTRY-A EUROPEAN JOURNAL

Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands

(2014) Karin Magnusson et al.   Prion

Evidence for Age-Dependent in Vivo Conformational Rearrangement within Aβ Amyloid Deposits

(2013) Sofie Nyström et al.   ACS Chemical Biology

“Prion-Like” Templated Misfolding in Tauopathies

(2013) Florence Clavaguera et al.   BRAIN PATHOLOGY

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

The Structural Basis for Optimal Performance of Oligothiophene-Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates

(2013) Therése Klingstedt et al.   CHEMISTRY-A EUROPEAN JOURNAL

Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

(2013) Götz Heilbronner et al.   EMBO REPORTS

Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls

(2013) Masahiro Maruyama et al.   NEURON

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

(2013) Florence Clavaguera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional characterization of two alpha-synuclein strains

(2013) Luc Bousset et al.   Nature Communications

Spectral Discrimination of Cerebral Amyloid Lesions after Peripheral Application of Luminescent Conjugated Oligothiophenes

(2012) Bettina M. Wegenast-Braun et al.   AMERICAN JOURNAL OF PATHOLOGY

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

The Amyloid-Congo Red Interface at Atomic Resolution

(2011) Anne K. Schütz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amyloid Structure: Conformational Diversity and Consequences

(2011) Brandon H. Toyama et al.   Annual Review of Biochemistry

Long-Term In Vivo Imaging of  -Amyloid Plaque Appearance and Growth in a Mouse Model of Cerebral  -Amyloidosis

(2011) J. K. Hefendehl et al.   JOURNAL OF NEUROSCIENCE

Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates

(2011) Therése Klingstedt et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Conjugated polymers for enhanced bioimaging

(2010) Therése Klingstedt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Novel Pentameric Thiophene Derivatives forin Vitroandin VivoOptical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses

(2009) Andreas Åslund et al.   ACS Chemical Biology

Structural Typing of Systemic Amyloidoses by Luminescent-Conjugated Polymer Spectroscopy

(2009) K. Peter R. Nilsson et al.   AMERICAN JOURNAL OF PATHOLOGY

Small organic probes as amyloid specific ligands - Past and recent molecular scaffolds

(2009) K. Peter R. Nilsson   FEBS LETTERS

Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

(2008) Chera L Maarouf et al.   Molecular Neurodegeneration

Molecular polymorphism of Aβ in Alzheimer's disease

(2008) Harry LeVine et al.   NEUROBIOLOGY OF AGING