Journal
ORGANIC LETTERS
Volume 18, Issue 21, Pages 5476-5479Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b02650
Keywords
-
Categories
Funding
- SDSU start up funds
- SDSU Presidential Leadership Fund
Ask authors/readers for more resources
Different catalysts are demonstrated to overcome or augment a substrate's innate regioselectivity. Nagasawa's bis-thiourea catalyst was found to overcome the innate para-selectivity of electrophilic phenol chlorination, yielding ortho-chlorinated phenols that are not readily obtainable-via canonical electrophilic chlorinations. Conversely, a phosphine sulfide derived from 2,2'-Bis(diphenyl-phosphino)-1,1'-binaphthyl (BINAP) was found to enhance the innate para-preference of phenol chlorination.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available