Journal
ORGANIC LETTERS
Volume 18, Issue 15, Pages 3906-3909Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b01947
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [NSFC21572272, NSFC21502232]
- Natural Science Foundation of Jiangsu Province [BK20140655]
- Foundation of State Key Laboratory of Natural Medicines [ZZYQ201605]
- Innovative Research Team in University [IRT_15R63]
Ask authors/readers for more resources
A palladium-catalyzed dearomative allylic alkylation of indoles with alkynes to construct indolenines with C3-quarternary centers was reported. The in situ formed arylallene intermediate omitted the need to install leaving groups on the allylic compounds and employ extra oxidants to oxidize the allylic C-H bonds. The reaction exhibited good functional group tolerance and high atom economy. Moreover, the reaction was further expanded to synthesize pyrroloindolines and furanoindolines.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available