Journal
ORGANIC LETTERS
Volume 18, Issue 14, Pages 3322-3325Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b01343
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Funding
- National Natural Science Foundation of China [21472136]
- Tianjin Research Program of Application Foundation and Advanced Technology [15JCZDJC32900]
- National Basic Research Project [2015CB856500]
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An unusual cascade reaction featuring annulation of diarylalkyne sulfonamides to form 5,10-dihydroindolo[3,2-b]indoles has been realized with Cu(OAc)(2) as the sole oxidant. This unprecedented process encompasses two sequential C-N bond formations, allowing for an efficient synthesis of the biologically important indoloindole derivatives.
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