4.8 Article

Ruthenium-Catalyzed Cross-Coupling of Maleimides with Alkenes

Journal

ORGANIC LETTERS
Volume 18, Issue 18, Pages 4598-4601

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b02244

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Funding

  1. MEXT
  2. JSPS KAKENHI Grant [JP16H01037, JP 24225002]
  3. JST (ACT-C), Japan
  4. Grants-in-Aid for Scientific Research [16H01037] Funding Source: KAKEN

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The cross-coupling of maleimides with electron-deficient alkenes such as acrylates proceeds smoothly under ruthenium catalysis. This unique C-C coupling provides a simple, straightforward synthetic method for preparing alkylidene succinimide derivatives.

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