Regiocontrolled synthesis of (hetero)aryl and alkenyl dehydropyrrolidines, dehydropiperidines and azepenes by Ru-catalyzed, heteroatom-directed α-C–H activation/cross-coupling of cyclic enamides with boronic acids
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Regiocontrolled synthesis of (hetero)aryl and alkenyl dehydropyrrolidines, dehydropiperidines and azepenes by Ru-catalyzed, heteroatom-directed α-C–H activation/cross-coupling of cyclic enamides with boronic acids
Authors
Keywords
-
Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 3, Pages 830-834
Publisher
Royal Society of Chemistry (RSC)
Online
2015-11-27
DOI
10.1039/c5ob02263k
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Ruthenium(II)-Catalyzed CH Arylation of Anilides with Boronic Acids, Borinic Acids and Potassium Trifluoroborates
- (2015) Jonathan Hubrich et al. ADVANCED SYNTHESIS & CATALYSIS
- Stereocontrolled synthesis of vicinally functionalized piperidines by nucleophilic β-addition of alkyllithiums to α-aryl substituted piperidine enecarbamates
- (2015) Timothy K. Beng et al. CHEMICAL COMMUNICATIONS
- Ruthenium(II)-Catalyzed C3 Arylation of 2-Aroylbenzofurans with Arylboronic Acids/Aryltrifluoroborates via Carbonyl-Directed C–H Bond Activation
- (2015) Dinesh J. Paymode et al. JOURNAL OF ORGANIC CHEMISTRY
- Cobalt-catalyzed arylation and alkenylation of alpha-bromo eneformamides and enecarbamates by cross-coupling with organic bromides: Application to the synthesis of functionalized piperidines and azepanes
- (2015) Daniel P. Bassler et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Trapping of carbolithiation-derived tertiary benzylic α-lithio piperidines with carbon electrophiles: Controlling the formation of α-amino quaternary and vicinal stereocenters
- (2015) Timothy K. Beng et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Expedient access to α,β-difunctionalized azepenes using α-halo eneformamides: application to the one-pot synthesis of 2-benzazepanes
- (2015) Daniel P. Bassler et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Direct access to functionalized benzotropones, azepanes, and piperidines by reductive cross-coupling of α-bromo enones with α-bromo enamides
- (2015) Timothy K. Beng et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- One-shot access to α,β-difunctionalized azepenes and dehydropiperidines by reductive cross-coupling of α-selenonyl-β-selenyl enamides with organic bromides
- (2015) Timothy K. Beng et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Diastereoselective synthesis of α,α,α′-trisubstituted pyrrolidines and piperidines by directed sequential lithiation/alkylation
- (2015) Timothy K. Beng et al. TETRAHEDRON LETTERS
- Direct Metal-Catalyzed Regioselective Functionalization of Enamides
- (2014) Nicolas Gigant et al. CHEMISTRY-A EUROPEAN JOURNAL
- Expedient Synthesis of α-Heteroaryl Piperidines Using a Pd-Catalyzed Suzuki Cross-Coupling–Reduction Sequence
- (2014) Kevin D. Hesp et al. ORGANIC LETTERS
- Direct Access to Functionalized Azepanes by Cross-Coupling with α-Halo Eneformamides
- (2014) Timothy K. Beng et al. ORGANIC LETTERS
- Vicinal difunctionalization of dehydropiperidines using α-chloro-β-sulfonyl eneformamides
- (2014) Timothy K. Beng et al. TETRAHEDRON LETTERS
- Ruthenium-Catalyzed α-(Hetero)Arylation of Saturated Cyclic Amines: Reaction Scope and Mechanism
- (2013) Aldo Peschiulli et al. CHEMISTRY-A EUROPEAN JOURNAL
- Removal of the Pyridine Directing Group from α-Substituted N-(Pyridin-2-yl)piperidines Obtained via Directed Ru-Catalyzed sp3 C–H Functionalization
- (2013) Veerle Smout et al. JOURNAL OF ORGANIC CHEMISTRY
- C(sp3)–H Bond Arylations Catalyzed by Well-Defined [Ru(O2CMes)2(p-cymene)]
- (2013) N. Y. Phani Kumar et al. JOURNAL OF ORGANIC CHEMISTRY
- Direct Site-Selective Arylation of Enamides via a Decarboxylative Cross-Coupling Reaction
- (2013) Nicolas Gigant et al. ORGANIC LETTERS
- Direct CH Functionalization of Enamides and Enecarbamates by Using Visible-Light Photoredox Catalysis
- (2012) Heng Jiang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Anodic Selective Functionalization of Cyclic Amine Derivatives
- (2012) Osamu Onomura HETEROCYCLES
- Synthetic Applications and Inversion Dynamics of Configurationally Stable 2-Lithio-2-arylpyrrolidines and -piperidines
- (2012) Timothy K. Beng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dynamics of Catalytic Resolution of 2-Lithio-N-Boc-piperidine by Ligand Exchange
- (2012) Timothy K. Beng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- An Experimental and in Situ IR Spectroscopic Study of the Lithiation–Substitution of N-Boc-2-phenylpyrrolidine and -piperidine: Controlling the Formation of Quaternary Stereocenters
- (2012) Nadeem S. Sheikh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Asymmetric Fluorination of Enamides: Access to α-Fluoroimines Using an Anionic Chiral Phase-Transfer Catalyst
- (2012) Robert J. Phipps et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Copper-Catalyzed Direct Arylation of Cyclic Enamides Using Diaryliodonium Salts
- (2012) Nicolas Gigant et al. ORGANIC LETTERS
- Use of Nonfunctionalized Enamides and Enecarbamates in Asymmetric Synthesis
- (2011) Kovuru Gopalaiah et al. CHEMICAL REVIEWS
- Catalytic Dynamic Resolution Applied to the Synthesis of 2,6-Disubstituted Piperidines: Preparation of (+)-Lupetidine and (–)-Epidihydropinidine
- (2011) Robert E. Gawley et al. HETEROCYCLES
- Enantioselective, Palladium-Catalyzed α-Arylation ofN-Boc Pyrrolidine:In SituReact IR Spectroscopic Monitoring, Scope, and Synthetic Applications
- (2011) Graeme Barker et al. JOURNAL OF ORGANIC CHEMISTRY
- Concise Enantiospecific, Stereoselective Syntheses of (+)-Crispine A and Its (−)-Antipode
- (2011) Mahender Gurram et al. JOURNAL OF ORGANIC CHEMISTRY
- Chiral Brønsted Acid Catalyzed Enantioselective α-Aminoxylation of Enecarbamates
- (2010) Min Lu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- C-2 Arylation of Piperidines through Directed Transition-Metal-Catalyzed sp3CH Activation
- (2010) Hana Prokopcová et al. CHEMISTRY-A EUROPEAN JOURNAL
- Regioselective and Stereoselective Copper(I)-Promoted Allylation and Conjugate Addition ofN-Boc-2-lithiopyrrolidine andN-Boc-2-lithiopiperidine
- (2010) Iain Coldham et al. JOURNAL OF ORGANIC CHEMISTRY
- Highly Enantioselective Catalytic Dynamic Resolution ofN-Boc-2-lithiopiperidine: Synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(−)-Coniine, (S)-(+)-Pelletierine, (+)-β-Conhydrine, and (S)-(−)-Ropivacaine and Formal Synthesis of (−)-Lasubine II and (+)-Cermizine C
- (2010) Timothy K. Beng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Total Synthesis of (−)-Aurantioclavine
- (2010) Katrien Brak et al. ORGANIC LETTERS
- Enantiomerization Dynamics and a Catalytic Dynamic Resolution ofN-Trimethylallyl-2-lithiopyrrolidine
- (2009) Timothy K. Beng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started