Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 15, Pages 3677-3680Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ob00231e
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- CONACYT [167092]
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The complete tetracyclic core structure of plicamine, a novel Amaryllidaceae-type alkaloid, was expeditously prepared by a Ugi four-component condensation reaction, followed by a one-pot sequential phenolic oxidation and intramolecular coupling process. The employment of this strategy resulted in a rapid, formal synthesis of (+/-)-plicamine.
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