Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 3, Pages 849-852Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ob02133b
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One of the most successful bioconjugation strategies to date is the copper(I)-catalyzed cycloaddition reaction (CuAAC), however, the typically applied reaction conditions have been found to degrade sensitive biomolecules. Herein, we present a water soluble copper chelator which can be utilized to protect biomolecules from copper induced degradation.
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