Molecular biology and genetics of embryonic eyelid development

Forces Generated by Cell Intercalation Tow Epidermal Sheets in Mammalian Tissue Morphogenesis

(2014) Evan Heller et al.   DEVELOPMENTAL CELL

NovelFREM1mutations expand the phenotypic spectrum associated with manitoba-oculo-tricho-anal (MOTA) syndrome and bifid nose renal agenesis anorectal malformations (BNAR) syndrome

(2013) Jared Nathanson et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Spry1 and Spry2 are necessary for eyelid closure

(2013) Murali R. Kuracha et al.   DEVELOPMENTAL BIOLOGY

Sphingosine 1-Phosphate Receptors Are Essential Mediators of Eyelid Closure during Embryonic Development

(2013) Deron R. Herr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

(2012) Giustina Ferone et al.   EMBO Molecular Medicine

Mutations inGRIP1cause Fraser syndrome

(2012) Maartje J Vogel et al.   JOURNAL OF MEDICAL GENETICS

Wakayama Symposium: Notch-FoxL2-α-SMA Axis in Eyelid Levator Muscle Development and Congenital Blepharophimosis

(2012) Chia-Yang Liu   Ocular Surface

Wakayama Symposium: Epithelial-Mesenchymal Interactions in Eyelid Development

(2012) Hideyo Ohuchi   Ocular Surface

Keratinocyte Migration in the Developing Eyelid Requires LIMK2

(2012) Dennis S. Rice et al.   PLoS One

Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closure

(2011) E. Geh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

(2011) K. S. Carmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity

(2010) Yeliz Boglev et al.   DEVELOPMENTAL BIOLOGY

Canonical Wnt/β-catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development

(2010) Amanda L. Zacharias et al.   DEVELOPMENTAL DYNAMICS

Glucocorticoid receptor antagonizes EGFR function to regulate eyelid development

(2010) Ana Sanchis et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis

(2009) Veronica G. Beaudry et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Spectrum ofp63mutations in a selected patient cohort affected with ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC)

(2009) Tuula Rinne et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

ΔNp63 knockdown mice: A mouse model for AEC syndrome

(2009) Maranke I. Koster et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate

(2009) J. Huang et al.   DEVELOPMENT

Molecular study of 33 families with Fraser syndrome new data and mutation review

(2008) M.M. van Haelst et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure

(2008) Zhengquan Yu et al.   DEVELOPMENTAL BIOLOGY

The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development

(2008) Philip J. Gage et al.   DEVELOPMENTAL BIOLOGY

Sorting Out the p63 Signaling Network

(2008) Maranke I. Koster et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2

(2008) J. Weng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dose- and Route-Dependent Teratogenicity, Toxicity, and Pharmacokinetic Profiles of the Hedgehog Signaling Antagonist Cyclopamine in the Mouse

(2008) Robert J. Lipinski et al.   TOXICOLOGICAL SCIENCES