UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy

Akt-Mediated Phosphorylation of XLF Impairs Non-Homologous End-Joining DNA Repair

(2015) Pengda Liu et al.   MOLECULAR CELL

Structural insights into NHEJ: Building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time

(2014) Gareth J. Williams et al.   DNA REPAIR

The clinical impact of deficiency in DNA non-homologous end-joining

(2014) Lisa Woodbine et al.   DNA REPAIR

DNA-PK: A dynamic enzyme in a versatile DSB repair pathway

(2014) Anthony J. Davis et al.   DNA REPAIR

Resistance of Glioblastoma-Initiating Cells to Radiation Mediated by the Tumor Microenvironment Can Be Abolished by Inhibiting Transforming Growth Factor-β

(2012) Matthew E. Hardee et al.   CANCER RESEARCH

Deregulation of E2-EPF Ubiquitin Carrier Protein in Papillary Renal Cell Carcinoma

(2011) Frederik C. Roos et al.   AMERICAN JOURNAL OF PATHOLOGY

DNA Damage Response and Growth Factor Signaling Pathways in Gliomagenesis and Therapeutic Resistance

(2011) M. Squatrito et al.   CANCER RESEARCH

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks

(2011) Mayura Meerang et al.   NATURE CELL BIOLOGY

Akt Activation Emulates Chk1 Inhibition and Bcl2 Overexpression and Abrogates G2 Cell Cycle Checkpoint by Inhibiting BRCA1 Foci

(2010) Ivana Tonic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdh1 Regulates Cell Cycle through Modulating the Claspin/Chk1 and the Rb/E2F1 Pathways

(2009) Daming Gao et al.   MOLECULAR BIOLOGY OF THE CELL

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

(2009) S. E. Golding et al.   MOLECULAR CANCER THERAPEUTICS

Advances in the genetics of glioblastoma: are we reaching critical mass?

(2009) Benjamin Purow et al.   Nature Reviews Neurology

AKT1 Inhibits Homologous Recombination by Inducing Cytoplasmic Retention of BRCA1 and RAD51

(2008) I. Plo et al.   CANCER RESEARCH

Activation of phosphoinositide 3-kinase by the NBS1 DNA repair protein through a novel activation motif

(2008) Yen-Chung Chen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma

(2008) Miao-Fen Chen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair

(2008) M. Toulany et al.   MOLECULAR CANCER THERAPEUTICS