miR-374a-CCND1-pPI3K/AKT-c-JUN feedback loop modulated by PDCD4 suppresses cell growth, metastasis and sensitizes nasopharyngeal carcinoma to cisplatin

miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR–p-PI3K/AKT-c-JUN

(2016) Mengyang Zhao et al.   Nature Communications

Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma

(2015) A. M. Walsh et al.   MOLECULAR CANCER RESEARCH

miRWalk2.0: a comprehensive atlas of microRNA-target interactions

(2015) Harsh Dweep et al.   NATURE METHODS

Decreased miRNA-637 is an unfavorable prognosis marker and promotes glioma cell growth, migration and invasion via direct targeting Akt1

(2015) T Que et al.   ONCOGENE

Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B

(2015) Kai-Ti Lin et al.   Nature Communications

miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β

(2015) Pengcheng Bu et al.   Nature Communications

miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth

(2015) Marija Mihailovich et al.   Nature Communications

Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the β-catenin/TCF complex association via FOXO3a activation

(2015) Yue Zhou et al.   Oncotarget

MiR-203 downregulation is responsible for chemoresistance in human glioblastoma by promoting epithelial-mesenchymal transition via SNAI2

(2015) Hongzhan Liao et al.   Oncotarget

EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN

(2014) L-M Cai et al.   ONCOGENE

MicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes

(2014) I Keklikoglou et al.   ONCOGENE

Epithelial–mesenchymal status renders differential responses to cisplatin in ovarian cancer

(2014) Q H Miow et al.   ONCOGENE

Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma

(2014) H Wang et al.   Cell Death & Disease

Axl-altered microRNAs regulate tumorigenicity and gefitinib resistance in lung cancer

(2014) Y Wang et al.   Cell Death & Disease

miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13

(2014) Peijing Zhang et al.   Nature Communications

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

(2014) Limo Chen et al.   Nature Communications

Effects of Differential Distribution of Microvessel Density, Possibly Regulated by miR-374a, on Breast Cancer Prognosis

(2013) Jian-Yi Li et al.   Asian Pacific Journal of Cancer Prevention

Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint

(2013) Xiaoming Ju et al.   CANCER RESEARCH

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

(2013) Changmeng Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma

(2013) Yan Zhen et al.   Cell Death & Disease

Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

(2013) X Yu et al.   Cell Death & Disease

PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma

(2013) Yan Ye et al.   Nature Communications

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

MEMO1, a new IRS1-interacting protein, induces epithelial–mesenchymal transition in mammary epithelial cells

(2012) A V Sorokin et al.   ONCOGENE

MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2

(2011) J. Lu et al.   CANCER RESEARCH

Identification of miR-374a as a prognostic marker for survival in patients with early-stage nonsmall cell lung cancer

(2011) Urmo Võsa et al.   GENES CHROMOSOMES & CANCER

miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes

(2011) Harsh Dweep et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Elevated expression of CDK4 in lung cancer

(2011) Aibing Wu et al.   Journal of Translational Medicine

Oncogenic EGFR Signaling Activates an mTORC2-NF- B Pathway That Promotes Chemotherapy Resistance

(2011) K. Tanaka et al.   Cancer Discovery

Cyclin D1/Cyclin-Dependent Kinase 4 Interacts with Filamin A and Affects the Migration and Invasion Potential of Breast Cancer Cells

(2010) Z. Zhong et al.   CANCER RESEARCH

DIFFERENTIALLY EXPRESSED MicroRNAs IN SMALL CELL LUNG CANCER

(2009) Edit Miko et al.   EXPERIMENTAL LUNG RESEARCH

Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response

(2008) K Lei et al.   ONCOGENE

siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression

(2008) N Bitomsky et al.   ONCOGENE