c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun

c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression

(2015) Michael A. Cantrell et al.   Oncotarget

JNK Signaling Mediates EPHA2-Dependent Tumor Cell Proliferation, Motility, and Cancer Stem Cell-like Properties in Non-Small Cell Lung Cancer

(2014) W. Song et al.   CANCER RESEARCH

JNK Suppresses Tumor Formation via a Gene-Expression Program Mediated by ATF2

(2014) Malgorzata Gozdecka et al.   Cell Reports

The Notch signaling pathway as a mediator of tumor survival

(2013) K. M. Capaccione et al.   CARCINOGENESIS

AP-1/c-Jun transcription factors: Regulation and function in malignant melanoma

(2013) Melanie Kappelmann et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Differential Regulation of c-Jun Protein Plays an Instrumental Role in Chemoresistance of Cancer Cells

(2013) Yan Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JNK-Induced Apoptosis, Compensatory Growth, and Cancer Stem Cells

(2012) F. Chen   CANCER RESEARCH

Discovery of Potent and Selective Covalent Inhibitors of JNK

(2012) Tinghu Zhang et al.   CHEMISTRY & BIOLOGY

c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells

(2012) C-H Yoon et al.   ONCOGENE

High ERK Protein Expression Levels Correlate with Shorter Survival in Triple-Negative Breast Cancer Patients

(2012) C. Bartholomeusz et al.   ONCOLOGIST

The Role of Cancer Stem Cells in Breast Cancer Initiation and Progression: Potential Cancer Stem Cell-Directed Therapies

(2012) Panagiota Economopoulou et al.   ONCOLOGIST

Evidence for Phenotypic Plasticity in Aggressive Triple-Negative Breast Cancer: Human Biology Is Recapitulated by a Novel Model System

(2012) Nicholas C. D’Amato et al.   PLoS One

JNK Signaling Promotes Intestinal Tumorigenesis Through Activation of mTOR Complex 1 in ApcΔ716 Mice

(2011) Teruaki Fujishita et al.   GASTROENTEROLOGY

JNK: A double-edged sword in tumorigenesis

(2011) Francisco Javier Cubero et al.   HEPATOLOGY

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?

(2011) Dejuan Kong et al.   Cancers

Regulation of Breast Cancer Stem Cell Activity by Signaling through the Notch4 Receptor

(2010) H. Harrison et al.   CANCER RESEARCH

Sustained c-Jun-NH2-Kinase Activity Promotes Epithelial-Mesenchymal Transition, Invasion, and Survival of Breast Cancer Cells by Regulating Extracellular Signal-Regulated Kinase Activation

(2010) J. Wang et al.   MOLECULAR CANCER RESEARCH

Targeting breast cancer stem cells

(2010) Sean P. McDermott et al.   Molecular Oncology

Elevated expression of phosphorylated c-Jun NH2-terminal kinase in basal-like and “triple-negative” breast cancers

(2009) Xiao Wang et al.   HUMAN PATHOLOGY

JNK1 activation predicts the prognostic outcome of the human hepatocellular carcinoma

(2009) Qingshan Chang et al.   Molecular Cancer

Mouse Models for Cancer Stem Cell Research

(2009) Le Cheng et al.   TOXICOLOGIC PATHOLOGY

Review Paper: Cancer Stem Cells and Cancer Nonstem Cells: From Adult Stem Cells or from Reprogramming of Differentiated Somatic Cells

(2009) J. E. Trosko   VETERINARY PATHOLOGY

The Humoral Immune System Has a Key Prognostic Impact in Node-Negative Breast Cancer

(2008) M. Schmidt et al.   CANCER RESEARCH

Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas

(2008) Jian Yi Li et al.   JOURNAL OF NEURO-ONCOLOGY

Cancer Stem Cell–Directed Therapies: Recent Data From the Laboratory and Clinic

(2008) Christopher Y Park et al.   MOLECULAR THERAPY