FOXO3 is essential for CD44 expression in pancreatic cancer cells

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Knockdown of CD44 inhibits the invasion and metastasis of hepatocellular carcinoma both in vitro and in vivo by reversing epithelial-mesenchymal transition

(2015) Yuan Gao et al.   Oncotarget

Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma

(2015) Maria Inés Molejon et al.   Oncotarget

Redox regulation of FoxO transcription factors

(2015) Lars-Oliver Klotz et al.   Redox Biology

Antibody Against CD44s Inhibits Pancreatic Tumor Initiation and Postradiation Recurrence in Mice

(2014) Ling Li et al.   GASTROENTEROLOGY

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

(2014) Andrea Viale et al.   NATURE

Intracellular autofluorescence: a biomarker for epithelial cancer stem cells

(2014) Irene Miranda-Lorenzo et al.   NATURE METHODS

A miRNA Signature of Chemoresistant Mesenchymal Phenotype Identifies Novel Molecular Targets Associated with Advanced Pancreatic Cancer

(2014) Alakesh Bera et al.   PLoS One

Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

(2013) Alexander Roesch et al.   CANCER CELL

Histological and prognostic importance of CD44+/CD24+/EpCAM+expression in clinical pancreatic cancer

(2013) Yusuke Ohara et al.   CANCER SCIENCE

Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer

(2013) G. Zhang et al.   CLINICAL CANCER RESEARCH

MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling

(2012) Sidong Huang et al.   CELL

Heterogeneity and Targeting of Pancreatic Cancer Stem Cells

(2012) V. R. Penchev et al.   CLINICAL CANCER RESEARCH

Identification of Pancreatic Cancer Stem Cells and Selective Toxicity of Chemotherapeutic Agents

(2012) Rama Adikrisna et al.   GASTROENTEROLOGY

Cell Specific CD44 Expression in Breast Cancer Requires the Interaction of AP-1 and NFκB with a Novel cis-Element

(2012) Shannon M. Smith et al.   PLoS One

Pancreatic Tumor Suppression by Benzyl Isothiocyanate Is Associated with Inhibition of PI3K/AKT/FOXO Pathway

(2011) S. R. Boreddy et al.   CLINICAL CANCER RESEARCH

Direct reprogramming of stem cell properties in colon cancer cells by CD44

(2011) Ying-Jhen Su et al.   EMBO JOURNAL

Effect of low-dose human atrial natriuretic peptide on postoperative atrial fibrillation in patients undergoing pulmonary resection for lung cancer: A double-blind, placebo-controlled study

(2011) Takashi Nojiri et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation

(2011) Craig A. Eyster et al.   MOLECULAR BIOLOGY OF THE CELL

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

(2011) Can Liu et al.   NATURE MEDICINE

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

(2011) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pancreatic cancer: understanding and overcoming chemoresistance

(2010) Zhiwei Wang et al.   Nature Reviews Gastroenterology & Hepatology

A Six-Gene Signature Predicts Survival of Patients with Localized Pancreatic Ductal Adenocarcinoma

(2010) Jeran K. Stratford et al.   PLOS MEDICINE

CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells

(2009) Sung Pil Hong et al.   INTERNATIONAL JOURNAL OF CANCER

Role of cancer stem cells in pancreatic ductal adenocarcinoma

(2009) Gregory Sergeant et al.   Nature Reviews Clinical Oncology

Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells

(2008) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOXO3a Turns the Tumor Necrosis Factor Receptor Signaling Towards Apoptosis Through Reciprocal Regulation of c-Jun N-Terminal Kinase and NF-κB

(2007) Hae-Young Lee et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY