MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation
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Title
MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation
Authors
Keywords
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Journal
ONCOGENE
Volume 36, Issue 13, Pages 1760-1769
Publisher
Springer Nature
Online
2016-10-17
DOI
10.1038/onc.2016.350
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Note: Only part of the references are listed.- SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma
- (2015) Laura Evans et al. CANCER LETTERS
- Retinoblastoma
- (2015) Helen Dimaras et al. Nature Reviews Disease Primers
- Retinoblastoma Progression
- (2015) David Cobrinik EBioMedicine
- Loss of photoreceptorness and gain of genomic alterations in retinoblastoma reveal tumor progression
- (2015) Irsan E. Kooi et al. EBioMedicine
- Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells
- (2014) W. O. Miles et al. EMBO JOURNAL
- Rb suppresses human cone-precursor-derived retinoblastoma tumours
- (2014) Xiaoliang L. Xu et al. NATURE
- The genomic landscape of retinoblastoma: a review
- (2013) Brigitte L Thériault et al. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Recurrent pre-existing and acquired DNA copy number alterations, including focalTERTgains, in neuroblastoma central nervous system metastases
- (2013) David Cobrinik et al. GENES CHROMOSOMES & CANCER
- Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies
- (2013) Diane E Rushlow et al. LANCET ONCOLOGY
- Neuroblastoma and MYCN
- (2013) M. Huang et al. Cold Spring Harbor Perspectives in Medicine
- Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development
- (2012) Kwong-Him To et al. BMC CANCER
- Molecular Pathways: Targeting Mdm2 and Mdm4 in Cancer Therapy
- (2012) Q. Li et al. CLINICAL CANCER RESEARCH
- Analysis of MDM2 and MDM4 Single Nucleotide Polymorphisms, mRNA Splicing and Protein Expression in Retinoblastoma
- (2012) Justina McEvoy et al. PLoS One
- Coexpression of Normally Incompatible Developmental Pathways in Retinoblastoma Genesis
- (2011) Justina McEvoy et al. CANCER CELL
- Targeting the p53 Pathway in Retinoblastoma with Subconjunctival Nutlin-3a
- (2011) R. C. Brennan et al. CANCER RESEARCH
- Newly identified aspects of tumor suppression by RB
- (2011) P. Viatour et al. Disease Models & Mechanisms
- Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation
- (2011) Nieves Embade et al. HEPATOLOGY
- MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells
- (2011) L Gu et al. ONCOGENE
- Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence
- (2010) Agustin Chicas et al. CANCER CELL
- High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma
- (2010) J. Carr-Wilkinson et al. CLINICAL CANCER RESEARCH
- The p53 orchestra: Mdm2 and Mdmx set the tone
- (2010) Mark Wade et al. TRENDS IN CELL BIOLOGY
- Retinoblastoma Has Properties of a Cone Precursor Tumor and Depends Upon Cone-Specific MDM2 Signaling
- (2009) Xiaoliang L. Xu et al. CELL
- Pifithrin-α protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53
- (2009) D Sohn et al. CELL DEATH AND DIFFERENTIATION
- p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug
- (2009) Shu-Ping Wang et al. NATURE CELL BIOLOGY
- Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/− mice
- (2009) Hongbo Wang et al. NATURE GENETICS
- A common gain of function of p53 cancer mutants in inducing genetic instability
- (2009) D P Liu et al. ONCOGENE
- Expression of p14ARF , MDM2 , and MDM4 in human retinoblastoma
- (2008) Ying Guo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss
- (2008) T. Terzian et al. GENES & DEVELOPMENT
- p53 mRNA controls p53 activity by managing Mdm2 functions
- (2008) Marco M. Candeias et al. NATURE CELL BIOLOGY
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