Serglycin in tumor microenvironment promotes non-small cell lung cancer aggressiveness in a CD44-dependent manner

Direct binding of hepatocyte growth factor and vascular endothelial growth factor to CD44v6

(2015) Y. Volz et al.   BIOSCIENCE REPORTS

Loss of PTPRM Associates with the Pathogenic Development of Colorectal Adenoma-Carcinoma Sequence

(2015) Putty-Reddy Sudhir et al.   Scientific Reports

CD44 Acts as a Signaling Platform Controlling Tumor Progression and Metastasis

(2015) Véronique Orian-Rousseau   Frontiers in Immunology

Serglycin Proteoglycan Is Required for Multiple Myeloma Cell Adhesion,in VivoGrowth, and Vascularization

(2014) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mass spectrometry-based serum peptide profiling in hepatocellular carcinoma with bone metastasis

(2014) Jian He   WORLD JOURNAL OF GASTROENTEROLOGY

Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β

(2013) Yazan Hassona et al.   CARCINOGENESIS

Cell-surface serglycin promotes adhesion of myeloma cells to collagen type I and affects the expression of matrix metalloproteinases

(2013) Antonis Skliris et al.   FEBS Journal

Serglycin (SRGN) overexpression predicts poor prognosis in hepatocellular carcinoma patients

(2013) Lu He et al.   MEDICAL ONCOLOGY

Serglycin Is Implicated in the Promotion of Aggressive Phenotype of Breast Cancer Cells

(2013) Angeliki Korpetinou et al.   PLoS One

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

CD44 Expressed on Cancer-Associated Fibroblasts Is a Functional Molecule Supporting the Stemness and Drug Resistance of Malignant Cancer Cells in the Tumor Microenvironment

(2013) Yumi Kinugasa et al.   STEM CELLS

Claudin-1 expression confers resistance to anoikis in colon cancer cells in a Src-dependent manner

(2012) Amar B. Singh et al.   CARCINOGENESIS

Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation

(2012) H-Y Lin et al.   CELL DEATH AND DIFFERENTIATION

CD99 is a novel prognostic stromal marker in non-small cell lung cancer

(2012) Karolina Edlund et al.   INTERNATIONAL JOURNAL OF CANCER

Claudin-1 induces epithelial–mesenchymal transition through activation of the c-Abl-ERK signaling pathway in human liver cells

(2012) Y Suh et al.   ONCOGENE

Claudin 1 Mediates TNFα-Induced Gene Expression and Cell Migration in Human Lung Carcinoma Cells

(2012) Atsushi Shiozaki et al.   PLoS One

Breast Cancer Cells Induce Stromal Fibroblasts to Secrete ADAMTS1 for Cancer Invasion through an Epigenetic Change

(2012) Shiaw-Wei Tyan et al.   PLoS One

Anti-apoptotic effect of claudin-1 on TNF-α-induced apoptosis in human breast cancer MCF-7 cells

(2012) Yang Liu et al.   TUMOR BIOLOGY

Cancer Associated Fibroblasts Exploit Reactive Oxygen Species Through a Proinflammatory Signature Leading to Epithelial Mesenchymal Transition and Stemness

(2011) Elisa Giannoni et al.   ANTIOXIDANTS & REDOX SIGNALING

Serglycin Is a Theranostic Target in Nasopharyngeal Carcinoma that Promotes Metastasis

(2011) X.-J. Li et al.   CANCER RESEARCH

Claudin-1 Up-regulates the Repressor ZEB-1 to Inhibit E-Cadherin Expression in Colon Cancer Cells

(2011) Amar B. Singh et al.   GASTROENTEROLOGY

Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells

(2011) L Y W Bourguignon et al.   ONCOGENE

Breast Cancer Cells Induce Cancer-Associated Fibroblasts to Secrete Hepatocyte Growth Factor to Enhance Breast Tumorigenesis

(2011) Shiaw-Wei Tyan et al.   PLoS One

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness

(2010) E. Giannoni et al.   CANCER RESEARCH

Cancer-associated fibroblasts and epithelial-mesenchymal transition in metastatic oral tongue squamous cell carcinoma

(2010) Marilena Vered et al.   INTERNATIONAL JOURNAL OF CANCER

Non-Small Cell Lung Cancer Cells Expressing CD44 Are Enriched for Stem Cell-Like Properties

(2010) Elaine Lai-Han Leung et al.   PLoS One

PDGF-C Mediates the Angiogenic and Tumorigenic Properties of Fibroblasts Associated with Tumors Refractory to Anti-VEGF Treatment

(2009) Yongping Crawford et al.   CANCER CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Claudin-1 Is a Metastasis Suppressor and Correlates with Clinical Outcome in Lung Adenocarcinoma

(2008) Yu-Chih Chao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Claudin 1 overexpression increases invasion and is associated with aggressive histological features in oral squamous cell carcinoma

(2008) Patricia Pintor dos Reis et al.   CANCER

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

CD44 Engagement Promotes Matrix-Derived Survival through the CD44-SRC-Integrin Axis in Lipid Rafts

(2008) J.-L. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY