Human EHMT2/G9a activates p53 through methylation-independent mechanism

KMT Set7/9 affects genotoxic stress response via the Mdm2 axis

(2015) Larissa Lezina et al.   Oncotarget

Lysine-specific modifications of p53: a matter of life and death?

(2015) Diana Marouco et al.   Oncotarget

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity

(2015) Tatiana N Moiseeva et al.   Oncotarget

KMTase Set7/9 is a critical regulator of E2F1 activity upon genotoxic stress

(2014) L Lezina et al.   CELL DEATH AND DIFFERENTIATION

H3K9 histone methyltransferase G9a-mediated transcriptional activation ofp21

(2014) Si-Taek Oh et al.   FEBS LETTERS

Limiting the power of p53 through the ubiquitin proteasome pathway

(2014) Vinod Pant et al.   GENES & DEVELOPMENT

Role of the lncRNA-p53 regulatory network in cancer

(2014) A. Zhang et al.   Journal of Molecular Cell Biology

Differences in Specificity and Selectivity Between CBP and p300 Acetylation of Histone H3 and H3/H4

(2013) Ryan A. Henry et al.   BIOCHEMISTRY

Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer

(2013) Chenfang Dong et al.   CANCER CELL

Defining the RGG/RG Motif

(2013) Palaniraja Thandapani et al.   MOLECULAR CELL

PPISURV: a novel bioinformatics tool for uncovering the hidden role of specific genes in cancer survival outcome

(2013) A V Antonov et al.   ONCOGENE

miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress

(2013) L Lezina et al.   Cell Death & Disease

Caspase-1 is a novel target of p63 in tumor suppression

(2013) I Celardo et al.   Cell Death & Disease

The p53 circuit board

(2012) Kelly D. Sullivan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

G9a, a multipotent regulator of gene expression

(2012) Shilpa Rani Shankar et al.   Epigenetics

Histone H3 Lysine 56 Methylation Regulates DNA Replication through Its Interaction with PCNA

(2012) Yongxin Yu et al.   MOLECULAR CELL

Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A

(2012) C.-P. Chaturvedi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G9a functions as a molecular scaffold for assembly of transcriptional coactivators on a subset of Glucocorticoid Receptor target genes

(2012) D. Bittencourt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic analysis of the 20S proteasome (PSMA3)-interacting proteins reveals a functional link between the proteasome and mRNA metabolism

(2011) Olga A. Fedorova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

p53 regulation by ubiquitin

(2011) Christopher L. Brooks et al.   FEBS LETTERS

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

A Distinct Mechanism for CoactivatorversusCorepressor Function by Histone Methyltransferase G9a in Transcriptional Regulation

(2011) Daniel J. Purcell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53-Dependent Transcription and Tumor Suppression Are Not Affected in Set7/9-Deficient Mice

(2011) Bernhard Lehnertz et al.   MOLECULAR CELL

The Methyltransferase Set7/9 (Setd7) Is Dispensable for the p53-Mediated DNA Damage Response In Vivo

(2011) Stefano Campaner et al.   MOLECULAR CELL

BioProfiling.de: analytical web portal for high-throughput cell biology

(2011) A. V. Antonov   NUCLEIC ACIDS RESEARCH

Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1)

(2011) Xiangyu Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptosis-promoted tumorigenesis:  -irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death

(2010) E. M. Michalak et al.   GENES & DEVELOPMENT

G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53

(2010) Jing Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A case study in cross-talk: the histone lysine methyltransferases G9a and GLP

(2010) Robert Collins et al.   NUCLEIC ACIDS RESEARCH

Histone H1 variant-specific lysine methylation by G9a/KMT1C and Glp1/KMT1D

(2010) Thomas Weiss et al.   Epigenetics & Chromatin

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins

(2009) Patrick Trojer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294

(2009) Yanqi Chang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes

(2008) Ping Xie et al.   CELLULAR SIGNALLING

CDYL Bridges REST and Histone Methyltransferases for Gene Repression and Suppression of Cellular Transformation

(2008) Peter Mulligan et al.   MOLECULAR CELL

Is there a code embedded in proteins that is based on post-translational modifications?

(2008) Robert J. Sims et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY