TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation

Non–Small Cell Lung Cancer

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The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer

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TFAP2C expression in breast cancer: correlation with overall survival beyond 10 years of initial diagnosis

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miR-33a functions as a tumor suppressor in melanoma by targeting HIF-1α

(2015) Jianda Zhou et al.   CANCER BIOLOGY & THERAPY

Wnt/β-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion

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TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis

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Inhibition of hedgehog signalling attenuates UVB-induced skin photoageing

(2015) Wanyeon Kim et al.   EXPERIMENTAL DERMATOLOGY

MiR-183 promotes growth of non-small cell lung cancer cells through FoxO1 inhibition

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Sumoylation Pathway Is Required to Maintain the Basal Breast Cancer Subtype

(2014) Maria V. Bogachek et al.   CANCER CELL

PAK1 Tyrosine Phosphorylation Is Required to Induce Epithelial-Mesenchymal Transition and Radioresistance in Lung Cancer Cells

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Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma

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TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis

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Integrated molecular portrait of non-small cell lung cancers

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Mir-33 regulates cell proliferation and cell cycle progression

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Significantly upregulated TACSTD2 and Cyclin D1 correlate with poor prognosis of invasive ductal breast cancer

(2012) Hong Lin et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Phosphorylation of Ribosomal Protein S3 and Antiapoptotic TRAF2 Protein Mediates Radioresistance in Non-small Cell Lung Cancer Cells

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Histone Demethylase KDM5B Collaborates with TFAP2C and Myc To Repress the Cell Cycle Inhibitor p21cip (CDKN1A)

(2012) P.-P. Wong et al.   MOLECULAR AND CELLULAR BIOLOGY

MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib

(2012) Ming-Hung Huang et al.   Molecular Oncology

Psoralidin, a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation

(2011) Hee Jung Yang et al.   BIOCHEMICAL PHARMACOLOGY

Identification of Genes Upregulated in ALK-Positive and EGFR/KRAS/ALK-Negative Lung Adenocarcinomas

(2011) H. Okayama et al.   CANCER RESEARCH

Inhibition of Ras for cancer treatment: the search continues

(2011) Antonio T Baines et al.   Future Medicinal Chemistry

PIM1-Activated PRAS40 Regulates Radioresistance in Non-small Cell Lung Cancer Cells through Interplay with FOXO3a, 14-3-3 and Protein Phosphatases

(2011) Wanyeon Kim et al.   RADIATION RESEARCH

Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells

(2010) George W. Woodfield et al.   GENES CHROMOSOMES & CANCER

Targeted therapy in non-small-cell lung cancer—is it becoming a reality?

(2010) Filip Janku et al.   Nature Reviews Clinical Oncology

Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction

(2010) Jun Hou et al.   PLoS One

Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells

(2009) He Ailan et al.   BMC CANCER

AP-2γ promotes proliferation in breast tumour cells by direct repression of the CDKN1A gene

(2009) Christopher M J Williams et al.   EMBO JOURNAL

SSeCKS/Gravin/AKAP12 Inhibits Cancer Cell Invasiveness and Chemotaxis by Suppressing a Protein Kinase C- Raf/MEK/ERK Pathway

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Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Loss of the ssecks/gravin/akap12 Gene Results in Prostatic Hyperplasia

(2008) S. Akakura et al.   CANCER RESEARCH

Overexpression ofTFAP2Cin invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival

(2008) JMW Gee et al.   JOURNAL OF PATHOLOGY

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Lung Cancer

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