Long-term consumption of an obesogenic high fat diet prior to ischemia-reperfusion mediates cardioprotection via Epac1-dependent signaling

Increased microvascular permeability in mice lacking Epac1 (Rapgef3)

(2016) R. K. Kopperud et al.   Acta Physiologica

The Coronary Circulation as a Target of Cardioprotection

(2016) Gerd Heusch   CIRCULATION RESEARCH

Sphingosine-1-Phosphate Signaling in Endothelial Disorders

(2016) Teresa Sanchez   Current Atherosclerosis Reports

Acute consumption of a high-fat diet prior to ischemia-reperfusion results in cardioprotection through NF-κB-dependent regulation of autophagic pathways

(2014) Lauren Haar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

High carbohydrate and high fat diets protect the heart against ischaemia/reperfusion injury

(2014) Ruduwaan Salie et al.   Cardiovascular Diabetology

cAMP with other signaling cues converges on Rac1 to stabilize the endothelial barrier— a signaling pathway compromised in inflammation

(2013) Nicolas Schlegel et al.   CELL AND TISSUE RESEARCH

Obesity paradox and the heart

(2013) Alban De Schutter et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Plasma Sphingosine-1-Phosphate Is Elevated in Obesity

(2013) Greg M. Kowalski et al.   PLoS One

High Fat Feeding in Mice Is Insufficient to Induce Cardiac Dysfunction and Does Not Exacerbate Heart Failure

(2013) Robert E. Brainard et al.   PLoS One

Obesity and the Obesity Paradox in Heart Failure

(2013) Adrienne L. Clark et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Body Mass Index and Mortality in Acute Myocardial Infarction Patients

(2012) Emily M. Bucholz et al.   AMERICAN JOURNAL OF MEDICINE

Obesity improves myocardial ischaemic tolerance and RISK signalling in insulin-insensitive rats

(2012) D. Donner et al.   Disease Models & Mechanisms

Fatty acids in cardiovascular health and disease: A comprehensive update

(2012) Seth J. Baum et al.   Journal of Clinical Lipidology

The Obesity Paradox, Cardiorespiratory Fitness, and Coronary Heart Disease

(2012) Paul A. McAuley et al.   MAYO CLINIC PROCEEDINGS

Endothelial Glycocalyx: Permeability Barrier and Mechanosensor

(2011) F. E. Curry et al.   ANNALS OF BIOMEDICAL ENGINEERING

Obesity paradox in elderly patients with cardiovascular diseases

(2011) Thomas E. Dorner et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inverse relation of body weight and weight change with mortality and morbidity in patients with type 2 diabetes and cardiovascular co-morbidity: An analysis of the PROactive study population

(2011) Wolfram Doehner et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Epac-Rap Signaling Reduces Cellular Stress and Ischemia-induced Kidney Failure

(2011) G. Stokman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Reduced Cardioprotective Action of Adiponectin in High-Fat Diet–Induced Type II Diabetic Mice and Its Underlying Mechanisms

(2010) Wei Yi et al.   ANTIOXIDANTS & REDOX SIGNALING

The cAMP binding protein Epac regulates cardiac myofilament function

(2009) O. Cazorla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ischaemic postconditioning protects isolated mouse hearts against ischaemia/reperfusion injury via sphingosine kinase isoform-1 activation

(2008) Z.-Q. Jin et al.   CARDIOVASCULAR RESEARCH

Epac Mediates β-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy

(2008) Mélanie Métrich et al.   CIRCULATION RESEARCH

Epac and Phospholipase Cϵ Regulate Ca2+Release in the Heart by Activation of Protein Kinase Cϵ and Calcium-Calmodulin Kinase II

(2008) Emily A. Oestreich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Myocardial Susceptibility to Repetitive Ischemia With High-fat diet-induced Obesit

(2008) Geeta D. Thakker et al.   Obesity

The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals

(2008) U. Yokoyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA