Open Targets: a platform for therapeutic target identification and validation
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Open Targets: a platform for therapeutic target identification and validation
Authors
Keywords
-
Journal
NUCLEIC ACIDS RESEARCH
Volume 45, Issue D1, Pages D985-D994
Publisher
Oxford University Press (OUP)
Online
2016-11-03
DOI
10.1093/nar/gkw1055
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Comparative Toxicogenomics Database: update 2017
- (2016) Allan Peter Davis et al. NUCLEIC ACIDS RESEARCH
- Disciplined approach to drug discovery and early development
- (2016) Robert M. Plenge Science Translational Medicine
- The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins
- (2016) Andrew D. Rouillard et al. Database-The Journal of Biological Databases and Curation
- Linking rare and common disease: mapping clinical disease-phenotypes to ontologies in therapeutic target validation
- (2016) Sirarat Sarntivijai et al. Journal of Biomedical Semantics
- In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities
- (2015) Carlota Rubio-Perez et al. CANCER CELL
- Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data
- (2015) Caroline F Wright et al. LANCET
- The support of human genetic evidence for approved drug indications
- (2015) Matthew R Nelson et al. NATURE GENETICS
- Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information
- (2015) Hong Yang et al. NUCLEIC ACIDS RESEARCH
- Expression Atlas update—an integrated database of gene and protein expression in humans, animals and plants
- (2015) Robert Petryszak et al. NUCLEIC ACIDS RESEARCH
- The Reactome pathway Knowledgebase
- (2015) Antonio Fabregat et al. NUCLEIC ACIDS RESEARCH
- Ensembl 2016
- (2015) Andrew Yates et al. NUCLEIC ACIDS RESEARCH
- Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
- (2014) David Cook et al. NATURE REVIEWS DRUG DISCOVERY
- COSMIC: exploring the world's knowledge of somatic mutations in human cancer
- (2014) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- Disease Ontology 2015 update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data
- (2014) Warren A. Kibbe et al. NUCLEIC ACIDS RESEARCH
- Gene Ontology Consortium: going forward
- (2014) NUCLEIC ACIDS RESEARCH
- OMIM.org: Online Mendelian Inheritance in Man (OMIM®), an online catalog of human genes and genetic disorders
- (2014) Joanna S. Amberger et al. NUCLEIC ACIDS RESEARCH
- Europe PMC: a full-text literature database for the life sciences and platform for innovation
- (2014) NUCLEIC ACIDS RESEARCH
- UniProt: a hub for protein information
- (2014) NUCLEIC ACIDS RESEARCH
- Standardized description of scientific evidence using the Evidence Ontology (ECO)
- (2014) M. C. Chibucos et al. Database-The Journal of Biological Databases and Curation
- Translational paradigms in pharmacology and drug discovery
- (2013) Kevin Mullane et al. BIOCHEMICAL PHARMACOLOGY
- The Enzyme Portal: a case study in applying user-centred design methods in bioinformatics
- (2013) Paula de Matos et al. BMC BIOINFORMATICS
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Phase II and Phase III attrition rates 2011–2012
- (2013) John Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Validating therapeutic targets through human genetics
- (2013) Robert M. Plenge et al. NATURE REVIEWS DRUG DISCOVERY
- DrugBank 4.0: shedding new light on drug metabolism
- (2013) Vivian Law et al. NUCLEIC ACIDS RESEARCH
- The ChEMBL bioactivity database: an update
- (2013) A. Patrícia Bento et al. NUCLEIC ACIDS RESEARCH
- The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data
- (2013) Sebastian Köhler et al. NUCLEIC ACIDS RESEARCH
- The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
- (2013) Danielle Welter et al. NUCLEIC ACIDS RESEARCH
- STITCH 4: integration of protein–chemical interactions with user data
- (2013) Michael Kuhn et al. NUCLEIC ACIDS RESEARCH
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- PhenoDigm: analyzing curated annotations to associate animal models with human diseases
- (2013) D. Smedley et al. Database-The Journal of Biological Databases and Curation
- Pharmacogenomics Knowledge for Personalized Medicine
- (2012) M Whirl-Carrillo et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Microattribution and nanopublication as means to incentivize the placement of human genome variation data into the public domain
- (2012) George P. Patrinos et al. HUMAN MUTATION
- Representation of rare diseases in health information systems: The orphanet approach to serve a wide range of end users
- (2012) Ana Rath et al. HUMAN MUTATION
- The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data
- (2012) Cynthia L. Smith et al. MAMMALIAN GENOME
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Use of genome-wide association studies for drug repositioning
- (2012) Philippe Sanseau et al. NATURE BIOTECHNOLOGY
- Bioinformatics Meets User-Centred Design: A Perspective
- (2012) Katrina Pavelin et al. PLoS Computational Biology
- SuperTarget goes quantitative: update on drug-target interactions
- (2011) N. Hecker et al. NUCLEIC ACIDS RESEARCH
- Modeling sample variables with an Experimental Factor Ontology
- (2010) James Malone et al. BIOINFORMATICS
- Reflections on drug research
- (2010) James Black BRITISH JOURNAL OF PHARMACOLOGY
- Evolution of the Sequence Ontology terms and relationships
- (2010) Christopher J. Mungall et al. JOURNAL OF BIOMEDICAL INFORMATICS
- Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana
- (2010) Insuk Lee et al. NATURE BIOTECHNOLOGY
- Harmonic Allocation of Authorship Credit: Source-Level Correction of Bibliometric Bias Assures Accurate Publication and Citation Analysis
- (2008) Nils T. Hagen PLoS One
- The receptor concept: pharmacology's big idea
- (2006) H P Rang BRITISH JOURNAL OF PHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now