Physiological TLR5 expression in the intestine is regulated by differential DNA binding of Sp1/Sp3 through simultaneous Sp1 dephosphorylation and Sp3 phosphorylation by two different PKC isoforms

Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity

(2015) Hua Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways

(2015) Nikhil N. Kulkarni et al.   MOLECULAR IMMUNOLOGY

Intestinal Epithelial Cell Toll-like Receptor 5 Regulates the Intestinal Microbiota to Prevent Low-Grade Inflammation and Metabolic Syndrome in Mice

(2014) Benoit Chassaing et al.   GASTROENTEROLOGY

Histone Hyperacetylation Up-regulates Protein Kinase Cδ in Dopaminergic Neurons to Induce Cell Death

(2014) Huajun Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flagellin Treatment Protects against Chemicals, Bacteria, Viruses, and Radiation

(2014) M. Vijay-Kumar et al.   JOURNAL OF IMMUNOLOGY

Innate and Adaptive Immunity Interact to Quench Microbiome Flagellar Motility in the Gut

(2013) Tyler C. Cullender et al.   Cell Host & Microbe

Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice

(2013) Myung H. Kim et al.   GASTROENTEROLOGY

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Acetylated Sp1 inhibits PTEN expression through binding to PTEN core promoter and recruitment of HDAC1 and promotes cancer cell migration and invasion

(2012) X.-X. Kou et al.   CARCINOGENESIS

Transcriptional regulation by post-transcriptional modification—Role of phosphorylation in Sp1 transcriptional activity

(2012) Shijian Chu   GENE

Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages

(2012) D. Shane O'Mahony et al.   International Journal of Medical Sciences

Phorbol esters enhance 1α,25-dihydroxyvitamin D3-regulated 25-hydroxyvitamin d-24-hydroxylase (CYP24A1) gene expression through ERK-mediated phosphorylation of specific protein 3 (Sp3) in Caco-2 cells

(2012) Yan Jiang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Toll-Like Receptor–Gut Microbiota Interactions: Perturb at Your Own Risk!

(2011) Frederic A. Carvalho et al.   Annual Review of Physiology

Butyrate Activates the cAMP-Protein Kinase A-cAMP Response Element-Binding Protein Signaling Pathway in Caco-2 Cells

(2011) Aihua Wang et al.   JOURNAL OF NUTRITION

Regulation of Inflammation by Short Chain Fatty Acids

(2011) Marco A.R. Vinolo et al.   Nutrients

Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health?

(2010) Kees Meijer et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Histone Modifiers, YY1 and p300, Regulate the Expression of Cartilage-specific Gene, Chondromodulin-I, in Mesenchymal Stem Cells

(2010) Tomoki Aoyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation

(2010) Danny CW Yu et al.   Molecular Cancer

Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line

(2010) Jennifer S Waby et al.   Molecular Cancer

Epithelial p38α Controls Immune Cell Recruitment in the Colonic Mucosa

(2010) Young Jun Kang et al.   PLoS Pathogens

Butyrate mediates nucleotide-binding and oligomerisation domain (NOD) 2-dependent mucosal immune responses against peptidoglycan

(2009) Chung-Hang Leung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

cAMP Stringently Regulates Human Cathelicidin Antimicrobial Peptide Expression in the Mucosal Epithelial Cells by Activating cAMP-response Element-binding Protein, AP-1, and Inducible cAMP Early Repressor

(2009) Krishnendu Chakraborty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sp1 Phosphorylation and Its Regulation of Gene Transcription

(2009) N. Y. Tan et al.   MOLECULAR AND CELLULAR BIOLOGY

Butyrate-induced phosphatase regulates VEGF and angiogenesis via Sp1

(2008) S. Prasanna Kumar et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Guardians of the Gut: Newly Appreciated Role of Epithelial Toll-Like Receptors in Protecting the Intestine

(2008) Matam Vijay-Kumar et al.   GASTROENTEROLOGY

Sp1 Is Required for Glucose-Induced Transcriptional Regulation of Mouse Vesicular Glutamate Transporter 2 Gene

(2008) Tao Li et al.   GASTROENTEROLOGY

Essential role of PKC  in histone deacetylase inhibitor-induced Epstein-Barr virus reactivation in nasopharyngeal carcinoma cells

(2008) H.-H. Lee et al.   JOURNAL OF GENERAL VIROLOGY

Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: Role in the cell cycle and apoptosis

(2007) Elisabet Selga et al.   BIOCHEMICAL PHARMACOLOGY