tRNA anticodon loop modifications ensure protein homeostasis and cell morphogenesis in yeast

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

(2015) Danny D. Nedialkova et al.   CELL

Urmylation and tRNA thiolation functions of ubiquitin-like Uba4·Urm1 systems are conserved from yeast to man

(2015) André Jüdes et al.   FEBS LETTERS

The Levels of a Universally Conserved tRNA Modification Regulate Cell Growth

(2015) Diego Rojas-Benitez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essentiality of threonylcarbamoyladenosine (t6A), a universal tRNA modification, in bacteria

(2015) Patrick C. Thiaville et al.   MOLECULAR MICROBIOLOGY

The role of wobble uridine modifications in +1 translational frameshifting in eukaryotes

(2015) Hasan Tükenmez et al.   NUCLEIC ACIDS RESEARCH

Phosphorylation of Elp1 by Hrr25 Is Required for Elongator-Dependent tRNA Modification in Yeast

(2015) Wael Abdel-Fattah et al.   PLoS Genetics

Erratum: Gut resistome development in healthy twin pairs in the first year of life

(2015) Aimee M. Moore et al.   Microbiome

Loss of Anticodon Wobble Uridine Modifications Affects tRNALys Function and Protein Levels in Saccharomyces cerevisiae

(2015) Roland Klassen et al.   PLoS One

Diversity of the biosynthesis pathway for threonylcarbamoyladenosine (t6A), a universal modification of tRNA

(2015) Patrick C Thiaville et al.   RNA Biology

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

(2014) Thomas M. Carlile et al.   NATURE

Functional importance of Ψ38and Ψ39in distinct tRNAs, amplified for tRNAGln(UUG)by unexpected temperature sensitivity of the s2U modification in yeast

(2014) Lu Han et al.   RNA

A Pseudouridine Residue in the Spliceosome Core Is Part of the Filamentous Growth Program in Yeast

(2014) Anindita Basak et al.   Cell Reports

tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding

(2013) V. A. N. Rezgui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling

(2013) Boris Zinshteyn et al.   PLoS Genetics

Biosynthesis and Function of Posttranscriptional Modifications of Transfer RNAs

(2012) Basma El Yacoubi et al.   Annual Review of Genetics

Cell Polarization and Cytokinesis in Budding Yeast

(2012) E. Bi et al.   GENETICS

The Regulation of Filamentous Growth in Yeast

(2012) Paul J. Cullen et al.   GENETICS

A yeast tRNA mutant that causes pseudohyphal growth exhibits reduced rates of CAG codon translation

(2012) Alain J. Kemp et al.   MOLECULAR MICROBIOLOGY

A cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification

(2012) Kenjyo Miyauchi et al.   Nature Chemical Biology

Modeling Huntington disease in yeast: Perspectives and future directions

(2012) Robert P. Mason et al.   Prion

Translational Control of Cell Division by Elongator

(2012) Fanelie Bauer et al.   Cell Reports

A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification

(2011) Basma El Yacoubi et al.   EMBO JOURNAL

Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs

(2011) Marie-Claire Daugeron et al.   NUCLEIC ACIDS RESEARCH

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

A dual function for chaperones SSB–RAC and the NAC nascent polypeptide–associated complex on ribosomes

(2010) Ansgar Koplin et al.   JOURNAL OF CELL BIOLOGY

Elongator function in tRNA wobble uridine modification is conserved between yeast and plants

(2010) Constance Mehlgarten et al.   MOLECULAR MICROBIOLOGY

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

The tRNA Modification Complex Elongator Regulates the Cdc42-Dependent Mitogen-Activated Protein Kinase Pathway That Controls Filamentous Growth in Yeast

(2009) Ummi Abdullah et al.   EUKARYOTIC CELL

Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4

(2009) Constance Mehlgarten et al.   MOLECULAR MICROBIOLOGY

Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA

(2009) Sebastian Leidel et al.   NATURE

The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA

(2009) B. El Yacoubi et al.   NUCLEIC ACIDS RESEARCH

Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions

(2009) Akiko Noma et al.   NUCLEIC ACIDS RESEARCH

Eukaryotic Wobble Uridine Modifications Promote a Functionally Redundant Decoding System

(2008) M. J. O. Johansson et al.   MOLECULAR AND CELLULAR BIOLOGY

Yeast α-tubulin suppressor Ats1/Kti13 relates to the Elongator complex and interacts with Elongator partner protein Kti11

(2008) René Zabel et al.   MOLECULAR MICROBIOLOGY

The primary target of the killer toxin fromPichia acaciaeis tRNAGln

(2008) Roland Klassen et al.   MOLECULAR MICROBIOLOGY

A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae

(2008) B. Huang et al.   RNA