The DDX6–4E-T interaction mediates translational repression and P-body assembly

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

(2016) Xinping Yang et al.   CELL

miRISC and the CCR4–NOT complex silence mRNA targets independently of 43S ribosomal scanning

(2016) Duygu Kuzuoğlu‐Öztürk et al.   EMBO JOURNAL

The Ccr4-Not complex is a key regulator of eukaryotic gene expression

(2016) Martine A. Collart   Wiley Interdisciplinary Reviews-RNA

Post-transcriptional regulation of gene expression by Unr: Table 1

(2015) Swagat Ray et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Relating sequence encoded information to form and function of intrinsically disordered proteins

(2015) Rahul K Das et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Not4-dependent translational repression is important for cellular protein homeostasis in yeast

(2015) S. Preissler et al.   EMBO JOURNAL

Modifiers of solid RNP granules control normal RNP dynamics and mRNA activity in early development

(2015) Arnaud Hubstenberger et al.   JOURNAL OF CELL BIOLOGY

A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis

(2015) Gianluca Amadei et al.   JOURNAL OF NEUROSCIENCE

P-body assembly requires DDX6 repression complexes rather than decay or Ataxin2/2L complexes

(2015) Jessica Ayache et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular Architecture of 4E-BP Translational Inhibitors Bound to eIF4E

(2015) Daniel Peter et al.   MOLECULAR CELL

Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes

(2015) Sybille Pfender et al.   NATURE

Towards a molecular understanding of microRNA-mediated gene silencing

(2015) Stefanie Jonas et al.   NATURE REVIEWS GENETICS

XenopusCAF1 requires NOT1-mediated interaction with 4E-T to repress translation in vivo

(2015) Shruti Waghray et al.   RNA

Architecture of the Ubiquitylation Module of the Yeast Ccr4-Not Complex

(2015) Varun Bhaskar et al.   STRUCTURE

Structure of a Human 4E-T/DDX6/CNOT1 Complex Reveals the Different Interplay of DDX6-Binding Proteins with the CCR4-NOT Complex

(2015) Sevim Ozgur et al.   Cell Reports

The eIF4E-Binding Protein 4E-T Is a Component of the mRNA Decay Machinery that Bridges the 5′ and 3′ Termini of Target mRNAs

(2015) Tamiko Nishimura et al.   Cell Reports

eIF4E-binding proteins: new factors, new locations, new roles

(2014) Anastasiia Kamenska et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Short Linear Motifs: Ubiquitous and Functionally Diverse Protein Interaction Modules Directing Cell Regulation

(2014) Kim Van Roey et al.   CHEMICAL REVIEWS

Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression

(2014) D. Bhandari et al.   GENES & DEVELOPMENT

A DDX6-CNOT1 Complex and W-Binding Pockets in CNOT9 Reveal Direct Links between miRNA Target Recognition and Silencing

(2014) Ying Chen et al.   MOLECULAR CELL

Structural and Biochemical Insights to the Role of the CCR4-NOT Complex and DDX6 ATPase in MicroRNA Repression

(2014) Hansruedi Mathys et al.   MOLECULAR CELL

Structural basis for the assembly of the Sxl–Unr translation regulatory complex

(2014) Janosch Hennig et al.   NATURE

An eIF4E1/4E-T Complex Determines the Genesis of Neurons from Precursors by Translationally Repressing a Proneurogenic Transcription Program

(2014) Guang Yang et al.   NEURON

ELAVL1 regulates alternative splicing of eIF4E transporter to promote postnatal angiogenesis

(2014) Sung-Hee Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1

(2014) Christopher Rouya et al.   RNA

4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation

(2014) Cátia Igreja et al.   Nature Communications

UNR facilitates the interaction of MLE with the lncRNA roX2 during Drosophila dosage compensation

(2014) Cristina Militti et al.   Nature Communications

Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

(2013) Marija Buljan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Mutations ineIF4ENIF1Are Associated With Primary Ovarian Insufficiency

(2013) Thushiga Kasippillai et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Serine-Threonine Kinase Receptor-Associated Protein (STRAP) Regulates Translation of Type I Collagen mRNAs

(2013) M. Vukmirovic et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by tristetraprolin

(2013) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing

(2013) A. Kamenska et al.   NUCLEIC ACIDS RESEARCH

Structural analysis of the yeast Dhh1–Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions

(2013) Humayun Sharif et al.   NUCLEIC ACIDS RESEARCH

Investigating the Consequences of eIF4E2 (4EHP) Interaction with 4E-Transporter on Its Cellular Distribution in HeLa Cells

(2013) Dorota Kubacka et al.   PLoS One

Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity

(2013) K. Feoktistova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of the Eukaryotic Translation Initiation Factor 4E-Transporter (4E-T) by c-Jun N-Terminal Kinase Promotes Stress-Dependent P-Body Assembly

(2012) M. Cargnello et al.   MOLECULAR AND CELLULAR BIOLOGY

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Multiple binding of repressed mRNAs by the P-body protein Rck/p54

(2012) M. Ernoult-Lange et al.   RNA

The DEAD-Box Protein Dhh1 Promotes Decapping by Slowing Ribosome Movement

(2012) Thomas Sweet et al.   PLOS BIOLOGY

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

(2011) R. Horos et al.   BLOOD

CUP promotes deadenylation and inhibits decapping of mRNA targets

(2011) C. Igreja et al.   GENES & DEVELOPMENT

AU-Rich-Element-Dependent Translation Repression Requires the Cooperation of Tristetraprolin and RCK/P54

(2011) M.-Y. Qi et al.   MOLECULAR AND CELLULAR BIOLOGY

Eukaryotic cold shock domain proteins: highly versatile regulators of gene expression

(2010) Marija Mihailovich et al.   BIOESSAYS

zif-1 translational repression defines a second, mutually exclusive OMA function in germline transcriptional repression

(2010) T. Guven-Ozkan et al.   DEVELOPMENT

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct functions of maternal and somatic Pat1 protein paralogs

(2010) A. Marnef et al.   RNA

Human Ccr4–Not complexes contain variable deadenylase subunits

(2009) Nga-Chi Lau et al.   BIOCHEMICAL JOURNAL

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

eIF4E: New Family Members, New Binding Partners, New Roles

(2009) Robert E. Rhoads   JOURNAL OF BIOLOGICAL CHEMISTRY

An eIF4E-binding protein regulates katanin protein levels inC. elegansembryos

(2009) Wei Li et al.   JOURNAL OF CELL BIOLOGY

Role of p54 RNA Helicase Activity and Its C-terminal Domain in Translational Repression, P-body Localization and Assembly

(2009) Nicola Minshall et al.   MOLECULAR BIOLOGY OF THE CELL

The SXL-UNR Corepressor Complex Uses a PABP-Mediated Mechanism to Inhibit Ribosome Recruitment to msl-2 mRNA

(2009) Kent E. Duncan et al.   MOLECULAR CELL

Structural Basis for the Mutually Exclusive Anchoring of P Body Components EDC3 and Tral to the DEAD Box Protein DDX6/Me31B

(2009) Felix Tritschler et al.   MOLECULAR CELL

Ectopic expression of eIF4E-transporter triggers the movement of eIF4E into P-bodies, inhibiting steady-state translation but not the pioneer round of translation

(2008) Hyung Chul Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS