Biophysical properties, thermal stability and functional impact of 8-oxo-7,8-dihydroguanine on oligonucleotides of RNA—a study of duplex, hairpins and the aptamer for preQ1as models

Synthesis, Thermal Stability, Biophysical Properties, and Molecular Modeling of Oligonucleotides of RNA Containing 2′-O-2-Thiophenylmethyl Groups

(2016) Joseph C. Nguyen et al.   JOURNAL OF ORGANIC CHEMISTRY

Entropic stabilization of folded RNA in crowded solutions measured by SAXS

(2016) Duncan Kilburn et al.   NUCLEIC ACIDS RESEARCH

Rates of Chemical Cleavage of DNA and RNA Oligomers Containing Guanine Oxidation Products

(2015) Aaron M. Fleming et al.   CHEMICAL RESEARCH IN TOXICOLOGY

5-Carboxamido-5-formamido-2-iminohydantoin, in Addition to 8-oxo-7,8-Dihydroguanine, Is the Major Product of the Iron-Fenton or X-ray Radiation-Induced Oxidation of Guanine under Aerobic Reducing Conditions in Nucleoside and DNA Contexts

(2015) Omar R. Alshykhly et al.   JOURNAL OF ORGANIC CHEMISTRY

The effect of RNA base lesions on mRNA translation

(2015) Alessandro Calabretta et al.   NUCLEIC ACIDS RESEARCH

The structural diversity of artificial genetic polymers

(2015) Irina Anosova et al.   NUCLEIC ACIDS RESEARCH

Biodiversity on the Rocks: Macrofauna Inhabiting Authigenic Carbonate at Costa Rica Methane Seeps

(2015) Lisa A. Levin et al.   PLoS One

Structure and function of preQ 1 riboswitches

(2014) Catherine D. Eichhorn et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Biophysical properties and thermal stability of oligonucleotides of RNA containing 7,8-dihydro-8-hydroxyadenosine

(2014) Ana M. Chauca-Diaz et al.   BIOPOLYMERS

Effects of 3'-OH and 5'-PO4 Base Mispairs and Damaged Base Lesions on the Fidelity of Nick Sealing by Deinococcus radiodurans RNA Ligase

(2014) B. J. Schmier et al.   JOURNAL OF BACTERIOLOGY

An Active Role for the Ribosome in Determining the Fate of Oxidized mRNA

(2014) Carrie L. Simms et al.   Cell Reports

Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure

(2013) Krishna C. Suddala et al.   NUCLEIC ACIDS RESEARCH

Synthesis of the Oligoribonucleotides Incorporating 8-Oxo-Guanosine and Evaluation of their Base Pairing Properties

(2013) Yohei Koga et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Recognition modes of RNA tetraloops and tetraloop-like motifs by RNA-binding proteins

(2013) Roopa Thapar et al.   Wiley Interdisciplinary Reviews-RNA

RNA modifications by oxidation: A novel disease mechanism?

(2012) Henrik E. Poulsen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molecular Mechanism of preQ1 Riboswitch Action: A Molecular Dynamics Study

(2012) Pavel Banáš et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Photochemical Control of RNA Structure by Disrupting π-Stacking

(2012) Marino J. E. Resendiz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pseudoknot Preorganization of the PreQ1 Class I Riboswitch

(2012) Tobias Santner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concise and efficient syntheses of preQ1 base, Q base, and (ent)-Q base

(2012) Hans-Dieter Gerber et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Comparison of a PreQ1Riboswitch Aptamer in Metabolite-bound and Free States with Implications for Gene Regulation

(2011) Jermaine L. Jenkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy

(2011) Anna Wacker et al.   NUCLEIC ACIDS RESEARCH

Characterization of DNA with an 8-oxoguanine modification

(2011) Sreelekha K. Singh et al.   NUCLEIC ACIDS RESEARCH

Structural architecture of an RNA that competitively inhibits RNase L

(2011) A. Y. Keel et al.   RNA

The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization

(2011) M. M. Duszczyk et al.   RNA

Free Energy Profile of RNA Hairpins: A Molecular Dynamics Simulation Study

(2010) Nan-Jie Deng et al.   BIOPHYSICAL JOURNAL

An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe

(2010) Mikiei Tanaka et al.   FREE RADICAL RESEARCH

Radical Chemistry of 8-Oxo-7,8-dihydro-2′-deoxyadenosine and 8-Oxo-7,8-dihydro-2′-deoxyguanosine: A Pulse Radiolysis Study

(2010) Thounaojam Avinash Singh et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Enzymatic Processing of Platinated RNAs

(2010) Erich G. Chapman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Folding of a transcriptionally acting PreQ1 riboswitch

(2010) U. Rieder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5′-triphosphate by bacterial and human RNA polymerases

(2009) Hiroyuki Kamiya et al.   FREE RADICAL BIOLOGY AND MEDICINE

Urinary excretion of biomarkers of oxidatively damaged DNA and RNA in hereditary hemochromatosis

(2009) Kasper Broedbaek et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Structural Basis for Recognition of the PreQ0Metabolite by an Unusually Small Riboswitch Aptamer Domain

(2009) Robert C. Spitale et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intraneuronal amyloid β accumulation and oxidative damage to nucleic acids in Alzheimer disease

(2009) Akihiko Nunomura et al.   NEUROBIOLOGY OF DISEASE

High-resolution NMR structure of an RNA model system: the 14-mer cUUCGg tetraloop hairpin RNA

(2009) Senada Nozinovic et al.   NUCLEIC ACIDS RESEARCH

Oxidatively Generated Damage to the Guanine Moiety of DNA: Mechanistic Aspects and Formation in Cells

(2008) Jean Cadet et al.   ACCOUNTS OF CHEMICAL RESEARCH

Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stress

(2008) Jinhua Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RNA under attack: Cellular handling of RNA damage

(2008) Elisabeth J. Wurtmann et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy

(2008) Tim Hofer et al.   EXPERIMENTAL GERONTOLOGY

Nucleic acid oxidation in Alzheimer disease

(2008) Paula I. Moreira et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sublethal RNA Oxidation as a Mechanism for Neurodegenerative Disease

(2008) Rudy Castellani et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dynamic Combinatorial Selection of Molecules Capable of Inhibiting the (CUG) Repeat RNA−MBNL1 Interaction In Vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1)

(2008) Peter C. Gareiss et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stability and Binding Properties of a Modified Thrombin Binding Aptamer

(2007) Bruno Pagano et al.   BIOPHYSICAL JOURNAL