RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis

Single-molecule imaging reveals a common mechanism shared by G-quadruplex–resolving helicases

(2016) Ramreddy Tippana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites

(2015) A. Piazza et al.   EMBO JOURNAL

Stability and Kinetics of c-MYC Promoter G-Quadruplexes Studied by Single-Molecule Manipulation

(2015) Huijuan You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the RNA Helicase MLE Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling

(2015) J. Rajan Prabu et al.   MOLECULAR CELL

Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase

(2015) Michael C. Chen et al.   NUCLEIC ACIDS RESEARCH

BLM unfolds G-quadruplexes in different structural environments through different mechanisms

(2015) Wen-Qiang Wu et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide–quadruplex complex

(2015) Brahim Heddi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation

(2015) X Gao et al.   Cell Death & Disease

Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development

(2015) Junwei Nie et al.   Cell Reports

Dynamics and stability of polymorphic human telomeric G-quadruplex under tension

(2014) Huijuan You et al.   NUCLEIC ACIDS RESEARCH

Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA

(2014) Ruobo Zhou et al.   eLife

Pif1 family helicases suppress genome instability at G-quadruplex motifs

(2013) Katrin Paeschke et al.   NATURE

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1

(2013) E. P. Booy et al.   NUCLEIC ACIDS RESEARCH

The DEAH-box helicase RHAU is an essential gene and critical for mouse hematopoiesis

(2012) J. C. Lai et al.   BLOOD

ATP Hydrolysis Enhances RNA Recognition and Antiviral Signal Transduction by the Innate Immune Sensor, Laboratory of Genetics and Physiology 2 (LGP2)

(2012) Annie M. Bruns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary

(2012) E. P. Booy et al.   NUCLEIC ACIDS RESEARCH

Improved High-Force Magnetic Tweezers for Stretching and Refolding of Proteins and Short DNA

(2011) Hu Chen et al.   BIOPHYSICAL JOURNAL

G4 Resolvase 1 tightly binds and unwinds unimolecular G4-DNA

(2011) Banabihari Giri et al.   NUCLEIC ACIDS RESEARCH

The DEAH-box RNA helicase RHAU binds an intramolecular RNA G‐quadruplex in TERC and associates with telomerase holoenzyme

(2011) Simon Lattmann et al.   NUCLEIC ACIDS RESEARCH

Yin Yang 1 contains G-quadruplex structures in its promoter and 5′-UTR and its expression is modulated by G4 resolvase 1

(2011) Weiwei Huang et al.   NUCLEIC ACIDS RESEARCH

Structural basis for the function of DEAH helicases

(2010) Yangzi He et al.   EMBO REPORTS

Transition dynamics and selection of the distinct S-DNA and strand unpeeling modes of double helix overstretching

(2010) Hongxia Fu et al.   NUCLEIC ACIDS RESEARCH

Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU

(2010) Simon Lattmann et al.   NUCLEIC ACIDS RESEARCH

Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism

(2010) M. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recruitment of the RNA Helicase RHAU to Stress Granules via a Unique RNA-binding Domain

(2008) Kateřina Chalupníková et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G4 Resolvase 1 Binds Both DNA and RNA Tetramolecular Quadruplex with High Affinity and Is the Major Source of Tetramolecular Quadruplex G4-DNA and G4-RNA Resolving Activity in HeLa Cell Lysates

(2008) Steven D. Creacy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability

(2008) Y. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Telomerase recruitment by the telomere end binding protein-β facilitates G-quadruplex DNA unfolding in ciliates

(2008) Katrin Paeschke et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

(2008) F. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA