A double-strand break can trigger immunoglobulin gene conversion

Multiple germline functional VL genes contribute to the IgL repertoire in ducks

(2016) Xiaoxing Guan et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Molecular analysis of the immunoglobulin genes in goose

(2016) Tian Huang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A method to convert mRNA into a gRNA library for CRISPR/Cas9 editing of any organism

(2016) H. Arakawa   Science Advances

Immunoglobulin genomics in the prairie vole (Microtus ochrogaster)

(2015) Tong Qin et al.   IMMUNOLOGY LETTERS

Characterization of antibody V segment diversity in the Tasmanian devil (Sarcophilus harrisii)

(2015) Beata Ujvari et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

High levels of BRC4 induced by a Tet-On 3G system suppress DNA repair and impair cell proliferation in vertebrate cells

(2014) Takuya Abe et al.   DNA REPAIR

GANP Regulates the Choice of DNA Repair Pathway by DNA-PKcs Interaction in AID-Dependent IgV Region Diversification

(2014) M. M. A. Eid et al.   JOURNAL OF IMMUNOLOGY

To Nick or Not to Nick: Comparison of I-SceI Single- and Double-Strand Break-Induced Recombination in Yeast and Human Cells

(2014) Samantha S. Katz et al.   PLoS One

Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair

(2014) L. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Of Somatic Hypermutation By immunoglobulin Enhancer And Enhancer-Like Sequences

(2014) Jean-Marie Buerstedde et al.   PLOS BIOLOGY

DNA Ligases I and III Cooperate in Alternative Non-Homologous End-Joining in Vertebrates

(2013) Katja Paul et al.   PLoS One

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy

(2013) Shailendra Kumar Singh et al.   Nature Communications

In vivo genome editing using a high-efficiency TALEN system

(2012) Victoria M. Bedell et al.   NATURE

Immunoglobulin Genomics in the Guinea Pig (Cavia porcellus)

(2012) Yongchen Guo et al.   PLoS One

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

(2011) Deniz Simsek et al.   PLoS Genetics

A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei

(2009) Catharine E. Boothroyd et al.   NATURE

Genetic Evidence for Single-Strand Lesions Initiating Nbs1-Dependent Homologous Recombination in Diversification of Ig V in Chicken B Lymphocytes

(2009) Makoto Nakahara et al.   PLoS Genetics

Engineering Variants of the I-SceI Homing Endonuclease with Strand-specific and Site-specific DNA-nicking Activity

(2008) Yan Niu et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway

(2008) C. M. Moure et al.   NUCLEIC ACIDS RESEARCH