αCP binding to a cytosine-rich subset of polypyrimidine tracts drives a novel pathway of cassette exon splicing in the mammalian transcriptome

Poly r(C) Binding Protein-1 is Central to Maintenance of Cancer Stem Cells in Prostate Cancer Cells

(2015) Qi Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Downregulated Poly-C binding protein-1 is a novel predictor associated with poor prognosis in Acute Myeloid Leukemia

(2015) Meifeng Zhou et al.   Diagnostic Pathology

ThePCBP1gene encoding poly(rc) binding protein i is recurrently mutated in Burkitt lymphoma

(2015) Rabea Wagener et al.   GENES CHROMOSOMES & CANCER

HOTAIR Long Noncoding RNA Promotes Gastric Cancer Metastasis through Suppression of Poly r(C)-Binding Protein (PCBP) 1

(2015) Z.-Z. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Global Promotion of Alternative Internal Exon Usage by mRNA 3′ End Formation Factors

(2015) Ashish Misra et al.   MOLECULAR CELL

Building Robust Transcriptomes with Master Splicing Factors

(2014) Mohini Jangi et al.   CELL

Context-dependent control of alternative splicing by RNA-binding proteins

(2014) Xiang-Dong Fu et al.   NATURE REVIEWS GENETICS

Mechanisms for U2AF to define 3′ splice sites and regulate alternative splicing in the human genome

(2014) Changwei Shao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Leveraging cross-link modification events in CLIP-seq for motif discovery

(2014) Emad Bahrami-Samani et al.   NUCLEIC ACIDS RESEARCH

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SchA–p85–FAK complex dictates isoform-specific activation of Akt2 and subsequent PCBP1-mediated post-transcriptional regulation of TGFβ-mediated epithelial to mesenchymal transition in human lung cancer cell line A549

(2014) Xinying Xue et al.   TUMOR BIOLOGY

Direct Competition between hnRNP C and U2AF65 Protects the Transcriptome from the Exonization of Alu Elements

(2013) Kathi Zarnack et al.   CELL

 CP Poly(C) Binding Proteins Act as Global Regulators of Alternative Polyadenylation

(2013) X. Ji et al.   MOLECULAR AND CELLULAR BIOLOGY

A compendium of RNA-binding motifs for decoding gene regulation

(2013) Debashish Ray et al.   NATURE

Genomic era analyses of RNA secondary structure and RNA-binding proteins reveal their significance to post-transcriptional regulation in plants

(2013) Ian M. Silverman et al.   PLANT SCIENCE

ILEI drives epithelial to mesenchymal transition and metastatic progression in the lung cancer cell line A549

(2013) Qi Song et al.   TUMOR BIOLOGY

Site identification in high-throughput RNA–protein interaction data

(2012) Philip J. Uren et al.   BIOINFORMATICS

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

THAP11, a novel binding protein of PCBP1, negatively regulates CD44 alternative splicing and cell invasion in a human hepatoma cell line

(2012) Wen-Xi Lian et al.   FEBS LETTERS

Down-Regulation of Poly(rC)-Binding Protein 1 Correlates With the Malignant Transformation of Hydatidiform Moles

(2012) Zhonghua Shi et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome

(2012) Anna Hegele et al.   MOLECULAR CELL

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data

(2012) Shihao Shen et al.   NUCLEIC ACIDS RESEARCH

An RNA-protein complex links enhanced nuclear 3′ processing with cytoplasmic mRNA stabilization

(2011) Xinjun Ji et al.   EMBO JOURNAL

A Disease-associated Polymorphism Alters Splicing of the Human CD45 Phosphatase Gene by Disrupting Combinatorial Repression by Heterogeneous Nuclear Ribonucleoproteins (hnRNPs)

(2011) Laura B. Motta-Mena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Semiquantitative Proteomic Analysis of the Human Spliceosome via a Novel Two-Dimensional Gel Electrophoresis Method

(2011) D. E. Agafonov et al.   MOLECULAR AND CELLULAR BIOLOGY

PCBP1 Suppresses the Translation of Metastasis-Associated PRL-3 Phosphatase

(2010) Haihe Wang et al.   CANCER CELL

PCBP-1 regulates alternative splicing of the CD44 gene and inhibits invasion in human hepatoma cell line HepG2 cells

(2010) Tong Zhang et al.   Molecular Cancer

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

TGF-β-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI

(2010) Arindam Chaudhury et al.   NATURE CELL BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Depletion of the Poly(C)-binding Proteins αCP1 and αCP2 from K562 Cells Leads to p53-independent Induction of Cyclin-dependent Kinase Inhibitor (CDKN1A) and G1Arrest

(2009) Shelly A. Waggoner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing

(2009) Claude C. Warzecha et al.   MOLECULAR CELL

Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

(2009) Yuanchao Xue et al.   MOLECULAR CELL

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

Identification of transcripts and translatants targeted by overexpressed PCBP1

(2008) Li-Rong Huo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

(2008) Donny D. Licatalosi et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS