A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor

Genetically encoded sensors enable real-time observation of metabolite production

(2016) Jameson K. Rogers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel screening methods—biosensors

(2015) Lothar Eggeling et al.   CURRENT OPINION IN BIOTECHNOLOGY

Design of an ectoine-responsive AraC mutant and its application in metabolic engineering of ectoine biosynthesis

(2015) Wei Chen et al.   METABOLIC ENGINEERING

Engineering an allosteric transcription factor to respond to new ligands

(2015) Noah D Taylor et al.   NATURE METHODS

Rosetta comparative modeling for library design: Engineering alternative inducer specificity in a transcription factor

(2015) Ramesh K. Jha et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Engineering Transcriptional Regulator Effector Specificity Using Computational Design and In Vitro Rapid Prototyping: Developing a Vanillin Sensor

(2015) Emmanuel L. C. de los Santos et al.   ACS Synthetic Biology

Evolution of enzyme catalysts caged in biomimetic gel-shell beads

(2014) Martin Fischlechner et al.   Nature Chemistry

Engineering anAcinetobacterregulon for biosensing and high-throughput enzyme screening inE. colivia flow cytometry

(2014) Ramesh K. Jha et al.   NUCLEIC ACIDS RESEARCH

Evolution-guided optimization of biosynthetic pathways

(2014) Srivatsan Raman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering allostery

(2014) Srivatsan Raman et al.   TRENDS IN GENETICS

Screening for Enhanced Triacetic Acid Lactone Production by Recombinant Escherichia coli Expressing a Designed Triacetic Acid Lactone Reporter

(2013) Shuang-Yan Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward a Generalized and High-throughput Enzyme Screening System Based on Artificial Genetic Circuits

(2013) Su-Lim Choi et al.   ACS Synthetic Biology

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Design and Application of a Mevalonate-Responsive Regulatory Protein

(2010) Shuang-Yan Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators

(2010) D. Lu et al.   GENES & DEVELOPMENT

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

(2010) J. J. Agresti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure prediction for CASP8 with all-atom refinement using Rosetta

(2009) Srivatsan Raman et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

RosettaLigand Docking with Full Ligand and Receptor Flexibility

(2008) Ian W. Davis et al.   JOURNAL OF MOLECULAR BIOLOGY

AraC Regulatory Protein Mutants with Altered Effector Specificity

(2008) Shuang-Yan Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY