DNA binding proteins explore multiple local configurations during docking via rapid rebinding

FRET-based assay to screen inhibitors of HIV-1 reverse transcriptase and nucleocapsid protein

(2016) Kamal K. Sharma et al.   NUCLEIC ACIDS RESEARCH

Reverse Transcriptase in Action: FRET-Based Assay for Monitoring Flipping and Polymerase Activity in Real Time

(2015) K. K. Sharma et al.   ANALYTICAL CHEMISTRY

Probing the Rate-Limiting Step for Intramolecular Transfer of a Transcription Factor between Specific Sites on the Same DNA Molecule by 15Nz-Exchange NMR Spectroscopy

(2014) Kyoung-Seok Ryu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of allosteric inhibition of HIV-1 reverse transcriptase revealed by single-molecule and ensemble fluorescence

(2014) Grant D. Schauer et al.   NUCLEIC ACIDS RESEARCH

Type II restriction endonucleases—a historical perspective and more

(2014) Alfred Pingoud et al.   NUCLEIC ACIDS RESEARCH

Molecular-crowding effects on single-molecule RNA folding/unfolding thermodynamics and kinetics

(2014) N. F. Dupuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A general mechanism for competitor-induced dissociation of molecular complexes

(2014) Thayaparan Paramanathan et al.   Nature Communications

Ultra-stable organic fluorophores for single-molecule research

(2013) Qinsi Zheng et al.   CHEMICAL SOCIETY REVIEWS

Binding Kinetics and Affinities of Heterodimeric versus Homodimeric HIV-1 Reverse Transcriptase on DNA–DNA Substrates at the Single-Molecule Level

(2013) Ryan A. Marko et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Impact of macromolecular crowding on DNA replication

(2013) Barak Akabayov et al.   Nature Communications

A Quantitative Model of ERK MAP Kinase Phosphorylation in Crowded Media

(2013) Kazuhiro Aoki et al.   Scientific Reports

Protein sliding and DNA denaturation are essential for DNA organization by human mitochondrial transcription factor A

(2012) Géraldine Farge et al.   Nature Communications

From Water and Ions to Crowded Biomacromolecules: In Vivo Structuring of a Prokaryotic Cell

(2011) J. Spitzer   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Target site cleavage by the monomeric restriction enzyme BcnI requires translocation to a random DNA sequence and a switch in enzyme orientation

(2011) Giedrius Sasnauskas et al.   NUCLEIC ACIDS RESEARCH

Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription

(2010) Shixin Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3′–5′ and 5′–3′ strands by rotating a single active site

(2010) Giedrius Sasnauskas et al.   NUCLEIC ACIDS RESEARCH

Spatio-temporal correlations can drastically change the response of a MAPK pathway

(2010) K. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin

(2010) B. Akabayov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stochastic reaction-diffusion kinetics in the microscopic limit

(2010) D. Fange et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonspecifically bound proteins spin while diffusing along DNA

(2009) Paul C Blainey et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics

Dynamic binding orientations direct activity of HIV reverse transcriptase

(2008) Elio A. Abbondanzieri et al.   NATURE

Sliding and jumping of single EcoRV restriction enzymes on non-cognate DNA

(2008) Isabelle Bonnet et al.   NUCLEIC ACIDS RESEARCH

Slide into Action: Dynamic Shuttling of HIV Reverse Transcriptase on Nucleic Acid Substrates

(2008) S. Liu et al.   SCIENCE