Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation

Insight into GATA1 transcriptional activity through interrogation ofciselements disrupted in human erythroid disorders

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Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation

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Aiolos Promotes Anchorage Independence by Silencing p66Shc Transcription in Cancer Cells

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Rictor Is Required for Early B Cell Development in Bone Marrow

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X-linked sideroblastic anemia due to ALAS2 intron 1 enhancer element GATA-binding site mutations

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Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation

(2013) L. Li et al.   BLOOD

Identification of a novel erythroid-specific enhancer for the ALAS2 gene and its loss-of-function mutation which is associated with congenital sideroblastic anemia

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Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

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Genome engineering using the CRISPR-Cas9 system

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Ldb1 complexes: the new master regulators of erythroid gene transcription

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Controlling Long-Range Genomic Interactions at a Native Locus by Targeted Tethering of a Looping Factor

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X-linked Sideroblastic Anemia Due to Carboxyl-terminal ALAS2 Mutations That Cause Loss of Binding to the β-Subunit of Succinyl-CoA Synthetase (SUCLA2)

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An integrated encyclopedia of DNA elements in the human genome

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Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

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Sideroblastic anemia: molecular analysis of the ALAS2 gene in a series of 29 probands and functional studies of 10 missense mutations

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Congenital Sideroblastic Anemias: Iron and Heme Lost in Mitochondrial Translation

(2011) M. D. Fleming   Hematology-American Society of Hematology Education Program

Hereditary sideroblastic anemia: pathophysiology and gene mutations

(2010) Hideo Harigae et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Systematic molecular genetic analysis of congenital sideroblastic anemia: Evidence for genetic heterogeneity and identification of novel mutations

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Isolation of Early Hematopoietic Stem Cells from Murine Yolk Sac and AGM

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