Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer

eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation

(2016) Amy S. Y. Lee et al.   NATURE

Rules of UGA-N decoding by near-cognate tRNAs and analysis of readthrough on short uORFs in yeast

(2016) Petra Beznosková et al.   RNA

Assembly of eIF3 Mediated by Mutually Dependent Subunit Insertion

(2016) M. Duane Smith et al.   STRUCTURE

A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism

(2016) Meera Shah et al.   Cell Reports

Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans

(2016) Douglas J. Cattie et al.   PLoS Genetics

The role of eIF3 and its individual subunits in cancer

(2015) John W.B. Hershey   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

5′ UTR m6A Promotes Cap-Independent Translation

(2015) Kate D. Meyer et al.   CELL

eIF3 targets cell-proliferation messenger RNAs for translational activation or repression

(2015) Amy S. Y. Lee et al.   NATURE

Structure of mammalian eIF3 in the context of the 43S preinitiation complex

(2015) Amedee des Georges et al.   NATURE

Translation initiation factor eIF3 promotes programmed stop codon readthrough

(2015) Petra Beznosková et al.   NUCLEIC ACIDS RESEARCH

The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis

(2015) Antonio M Rezende et al.   BMC GENOMICS

The Scanning Mechanism of Eukaryotic Translation Initiation

(2014) Alan G. Hinnebusch   Annual Review of Biochemistry

The Translation Initiation Factor eIF3i Up-regulates Vascular Endothelial Growth Factor A, Accelerates Cell Proliferation, and Promotes Angiogenesis in Embryonic Development and Tumorigenesis

(2014) Yike Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional and Biochemical Characterization of Human Eukaryotic Translation Initiation Factor 3 in Living Cells

(2014) Susan Wagner et al.   MOLECULAR AND CELLULAR BIOLOGY

Fail-safe mechanism of GCN4 translational control—uORF2 promotes reinitiation by analogous mechanism to uORF1 and thus secures its key role in GCN4 expression

(2014) Stanislava Gunišová et al.   NUCLEIC ACIDS RESEARCH

Eukaryotic translation initiation factors in cancer development and progression

(2013) Rita Spilka et al.   CANCER LETTERS

Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29

(2013) Yaser Hashem et al.   CELL

Spectrin Domain of Eukaryotic Initiation Factor 3a Is the Docking Site for Formation of the a:b:i:g Subcomplex

(2013) Zizheng Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The m Subunit of Murine Translation Initiation Factor eIF3 Maintains the Integrity of the eIF3 Complex and Is Required for Embryonic Development, Homeostasis, and Organ Size Control

(2013) Liyong Zeng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit

(2013) Yaser Hashem et al.   NATURE

Regulation of plant translation by upstream open reading frames

(2013) Albrecht G. von Arnim et al.   PLANT SCIENCE

Human-Like Eukaryotic Translation Initiation Factor 3 from Neurospora crassa

(2013) M. Duane Smith et al.   PLoS One

Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis

(2013) A. Choudhuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture of Human Translation Initiation Factor 3

(2013) Jordi Querol-Audi et al.   STRUCTURE

Translation Initiation Factors eIF3 and HCR1 Control Translation Termination and Stop Codon Read-Through in Yeast Cells

(2013) Petra Beznosková et al.   PLoS Genetics

‘Ribozoomin’ – Translation Initiation from the Perspective of the Ribosome-bound Eukaryotic Initiation Factors (eIFs)

(2012) Leos Shivaya Valasek   CURRENT PROTEIN & PEPTIDE SCIENCE

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling

(2011) Derek E. Gildea et al.   FASEB JOURNAL

Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly

(2011) Anna Herrmannová et al.   NUCLEIC ACIDS RESEARCH

Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)

(2011) C. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translation Reinitiation Relies on the Interaction between eIF3a/TIF32 and Progressively Folded cis-Acting mRNA Elements Preceding Short uORFs

(2011) Vanda Munzarová et al.   PLoS Genetics

The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection

(2010) Latifa ElAntak et al.   JOURNAL OF MOLECULAR BIOLOGY

The RNA Recognition Motif of Eukaryotic Translation Initiation Factor 3g (eIF3g) Is Required for Resumption of Scanning of Posttermination Ribosomes for Reinitiation on GCN4 and Together with eIF3i Stimulates Linear Scanning

(2010) L. Cuchalova et al.   MOLECULAR AND CELLULAR BIOLOGY

PCI Complexes: Beyond the Proteasome, CSN, and eIF3 Troika

(2009) Elah Pick et al.   MOLECULAR CELL

The eIF3 Interactome Reveals the Translasome, a Supercomplex Linking Protein Synthesis and Degradation Machineries

(2009) Zhe Sha et al.   MOLECULAR CELL

eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA

(2008) B. Szamecz et al.   GENES & DEVELOPMENT

Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3

(2008) M. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fission yeast translation initiation factor 3 subunit eIF3h is not essential for global translation initiation, but deletion ofeif3h+affects spore formation

(2008) Anirban Ray et al.   YEAST