Article
Engineering, Electrical & Electronic
Deepti Sharma, Vikrant Kaim, Binod Kumar Kanaujia, Neeta Singh, Sachin Kumar, Karumudi Rambabu
Summary: This article presents a compact circularly polarized fractal-shaped open-loop antenna for leadless cardiac transcatheter pacing system, operating in three different frequency bands. The antenna's design and performance have significant implications in the field of implantable antennas.
IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION
(2022)
Article
Engineering, Electrical & Electronic
Deepti Sharma, Sachin Kumar, Neeta Singh, Binod Kumar Kanaujia, Satya P. Singh, Aime Lay-Ekuakille
Summary: Wireless power transfer (WPT) systems are becoming popular for powering advanced multifunctional biomedical implantable devices. This article presents a WPT system that includes an antenna array and a rectenna, which is integrated inside an implanted leadless pacemaker's capsule. The system operates in dual bands and has the smallest footprint compared to other implantable rectennas.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2023)
Article
Clinical Neurology
Abdallah Fayssoil, Arnaud Lazarus, Karim Wahbi, Bernard Clair, Nicolas Mansencal, David Orlikowski
Summary: Duchenne muscular dystrophy (DMD) is an X-linked genetic disease related to dystrophin deficiency, which can affect heart and respiratory function, with the possibility of severe atrio-ventricular block in some cases. The implantation of a leadless intra-cardiac trans-catheter pacing system was successfully performed in an adult DMD patient using a wheelchair and permanent home mechanical ventilation.
NEUROMUSCULAR DISORDERS
(2021)
Article
Cardiac & Cardiovascular Systems
Maully J. Shah, Alejandro A. Borquez, Daniel Cortez, Anthony C. McCanta, Paolo De Filippo, Robert D. Whitehill, Jason R. Imundo, Jeremy P. Moore, Elizabeth D. Sherwin, Taylor S. Howard, Eric Rosenthal, Naomi J. Kertesz, Philip M. Chang, Nandini Madan, Steven P. Kutalek, Benjamin H. Hammond, Christopher M. Janson, V. Ramesh Iyer, Matthew R. Williams
Summary: This study retrospectively collected data from 15 centers to evaluate the clinical indications, procedural characteristics, electrical performance, and outcomes of leadless pacemaker (TLP) implantation in children. The results showed a high success rate of TLP implantation in children, stable electrical parameters, and few major complications.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Mikhael F. El-Chami, Christophe Garweg, Saverio Iacopino, Faisal Al-Samadi, Jose Luis Martinez-Sande, Claudio Tondo, Jens Brock Johansen, Xavier Vinolas Prat, Jonathan P. Piccini, Yong Mei Cha, Eric Grubman, Pierre Bordachar, Paul R. Roberts, Kyoko Soejima, Kurt Stromberg, Dedra H. Fagan, Nicolas Clementy
Summary: Implant of Micra appears to be safe and feasible regardless of interrupted or continued periprocedural oral anticoagulation (AC) strategy, with no increased risk of perforation or vascular complications.
Article
Cardiac & Cardiovascular Systems
Hong-Xia Niu, Xi Liu, Min Gu, Xuhua Chen, Chi Cai, Minsi Cai, Shu Zhang, Wei Hua
Summary: CSP achieved shorter paced QRS duration and better cardiac structure and function in post-TAVR patients than RVP. LBBP had a higher implant success rate and better pacing parameters than HBP.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Robert G. Hauser, Charles C. Gornick, Raed H. Abdelhadi, Chuen Y. Tang, Susan A. Casey, Jay D. Sengupta
Summary: Leadless intracardiac pacemakers like the Medtronic Micra were developed to reduce complications. However, a study comparing MACE associated with Micra implantation to CapSureFix transvenous pacing leads found a higher incidence of major adverse clinical events with Micra, including higher rates of tamponade, death, and the need for rescue thoracotomies. Micra patients also had higher rates of complications such as requiring CPR and suffering from hypotension or shock compared to CapSureFix recipients.
Article
Engineering, Biomedical
Adrian Ryser, Tobias Schmid, Lukas Bereuter, Juergen Burger, Tobias Reichlin, Thomas Niederhauser, Andreas Haeberlin
Summary: This study analyzes the performance of two low-power modulation techniques in intracardiac communication and demonstrates the feasibility of CIC-based synchronization for multi-chamber leadless cardiac pacemakers. BB-MAN or OOK modulation techniques are preferable due to their efficient signal transmission and reduced complexity.
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS
(2022)
Article
Cardiac & Cardiovascular Systems
David Backhoff, Matthias J. Muller, Yannic Wilberg, Katja Eildermann, Thomas Paul, Dieter Zenker, Ulrich Krause
Summary: This study examined the feasibility of epicardial implantation of a leadless pacemaker in a growing animal model. The results showed satisfactory short-term outcomes, but during mid-term follow-up, there was an increase in pacing thresholds and loss of capture in some animals. There was also concern regarding deep penetration of the device into the myocardium. The current shape of the Micra transcatheter pacing system makes it unsuitable for epicardial placement in growing organisms.
Review
Medicine, General & Internal
Sijin Wu, Yuanhao Jin, Wenzhao Lu, Zhongli Chen, Yan Dai, Keping Chen
Summary: Leadless pacemakers with atrioventricular synchronous pacing demonstrate favorable safety and efficacy, as evidenced by several small-scale observational studies. This systematic review and meta-analysis evaluates the efficacy and safety of this new technology. The results show a high proportion of atrioventricular synchrony after implantation and a significant increase in cardiac output. The overall incidence of complications is low, indicating the potential for widespread adoption in clinical practice.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Physiology
Marina Strocchi, Nadeev Wijesuriya, Mark K. Elliott, Karli Gillette, Aurel Neic, Vishal Mehta, Edward J. Vigmond, Gernot Plank, Christopher A. Rinaldi, Steven A. Niederer
Summary: Biventricular endocardial pacing and left bundle pacing are new delivery methods for cardiac resynchronization therapy. Leadless pacing can be used to avoid risks associated with traditional lead systems. This study investigated the impact of RV-LV delay, RV lead location, and left bundle capture on the efficacy of leadless pacing.
FRONTIERS IN PHYSIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Paul Nona, Mahmoud Altawil, Essaq Khan, Waddah Maskoun
Summary: An elderly patient with dual-chamber pacemaker presented with symptomatic bradycardia and high-grade AV block. Due to lead malfunction and his age-related conditions, a Micra AV pacemaker was implanted while programming the existing pacemaker to AAIR mode for maintaining AV synchrony.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Paul R. Roberts, Christophe Garweg, Arthur M. Yue, Alexander R. Mattson, Ramesh Raghupathy, Jonathan P. Piccini
Summary: This study demonstrates that the updated Micra catheter with increased surface area and rounding of the tip improves preclinical perforation performance. Further evaluation with robust registry data is necessary to assess the impact of these catheter design changes.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Mikhael F. El-Chami, Lindsay Bockstedt, Colleen Longacre, Lucas Higuera, Kurt Stromberg, George Crossley, Robert C. Kowal, Jonathan P. Piccini
Summary: The Micra leadless VVI pacemaker showed lower rates of reinterventions and chronic complications compared to transvenous VVI pacing in a real-world study of US Medicare patients, with no difference in all-cause mortality at 2 years.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Thibault Lenormand, Kassem Abou Khalil, Alexandre Bodin, Dominique Babuty, Arnaud Bisson, Nicolas Clementy
Summary: This retrospective study evaluated the safety and efficacy of leadless pacemakers in older and newer generation patients. The implantation success rate was high and complication rate was low, indicating that leadless pacemakers are a safe and efficient alternative to conventional transvenous pacemakers.
ARCHIVES OF CARDIOVASCULAR DISEASES
(2023)
Article
Cardiac & Cardiovascular Systems
Travis D. Richardson, Ricardo M. Lugo, George H. Crossley, Christopher R. Ellis
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Mikhael F. El-Chami, Jane Mayotte, Matt Bonner, Reece Holbrook, Kurt Stromberg, Muhammad Rizwan Sohail
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2020)
Letter
Cardiac & Cardiovascular Systems
Mikhael F. El-Chami, Jane Mayotte, Matt Bonner, Reece Holbrook, Kurt Stromberg, M. Rizwan Sohail
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
John Hummel, Atul Verma, Hugh Calkins, Lee H. Schwamm, Daryl Gress, Darryl Wells, Joseph Souza, Robert B. Hokanson, Lauren Hemingway, Kurt Stromberg, Robert Hoyt, Andrew Wickliffe, David DeLurgio, Lucas Boersma
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2020)
Article
Economics
John D. Rogers, Christopher Piorkowski, M. Rizwan Sohail, Rishi Anand, Marcin Kowalski, Sarah Rosemas, Kurt Stromberg, Prashanthan Sanders
JOURNAL OF MEDICAL ECONOMICS
(2020)
Article
Cardiac & Cardiovascular Systems
Sara M. Negrotto, Ricardo M. Lugo, Mohamed Metawee, Arvindh N. Kanagasundram, Geoffrey Chidsey, Michael T. Baker, Gregory F. Michaud, Robert N. Piana, Moore Benjamin Shoemaker, Christopher Randall Ellis
Summary: Nonchicken wing (windsock and broccoli) left atrial appendage morphology is associated with higher risk of left atrial appendage thrombus formation, with female patients and those with left atrial appendage ejection velocity < 20 cm/s at increased risk. Concomitant anticoagulant use and higher left ventricular ejection fraction are associated with lower risk.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Christopher R. Ellis
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Majd A. El-Harasis, Rachel E. Schreier, Jodi M. Orton, Christopher R. Ellis
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Samir Saba, Devi Nair, Christopher R. Ellis, Allen Ciuffo, Marilyn Cox, Nigel Gupta, Saumya Sharma, Sandeep Jain, Marshall Winner, Sharda Mehta, Torri Simon, Ken Stein, Kenneth A. Ellenbogen
Summary: In CRT nonresponders, the use of the LV MSP feature is safe and associated with a conversion rate of around 50%, with only a small projected reduction in CRT-defibrillator battery longevity. LV MSP should be considered in the management of CRT nonresponders.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Jason A. Cook, Megan C. Lancaster, Arvindh N. Kanagasundram, Heather L. Prigmore, Kim L. Sandler, Robert J. Deegan, Christopher R. Ellis
Summary: This study found that elevation of BNP in patients with AF is associated with left atrial appendage size and function, but not with CHADS2-VASc score or appendage morphology, after considering changes in left atrial pressure (LAP).
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Christopher R. Ellis, Arnold J. Greenspon, John A. Andriulli, Paul A. Gould, Roger G. Carillo, Matthew J. Kolek, Rachel Donegan, Ansel P. Amaral, Suneet Mittal
Summary: This study investigated the need for antibiotic pocket irrigation and postoperative oral antibiotics in CIED surgery. The results showed that there were no additional benefits of antibiotic pocket irrigation and postoperative oral antibiotics compared to standard measures. Furthermore, postoperative hematoma was identified as a major risk factor for infection.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Serge Boveda, Lucas Higuera, Colleen Longacre, Claudia Wolff, Kael Wherry, Kurt Stromberg, Mikhael F. El-Chami
Summary: This study compares the clinical outcomes between leadless pacemakers and transvenous ventricular pacemakers in subgroups of patients at higher risk of pacemaker complications. The results show that leadless pacemakers have lower rates of complications and reinterventions in several high-risk subgroups compared to transvenous ventricular pacemakers.
Letter
Cardiac & Cardiovascular Systems
Arvindh N. Kanagasundram, Christopher R. Ellis
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Shephal K. K. Doshi, Saibal Kar, Ashish Sadhu, Rodney Horton, Jose Osorio, Christopher Ellis, James Stone Jr, Manish Shah, Srinivas R. R. Dukkipati, Stuart Adler, Devi G. G. Nair, Jamie Kim, Oussama Wazni, Matthew J. J. Price, David R. R. Holmes Jr, Robert Shipley, Thomas Christen, Dominic J. J. Allocco, Vivek Y. Y. Reddy
Summary: The PINNACLE FLX trial evaluated the safety and efficacy of the WATCHMAN FLX left atrial appendage closure device, and it achieved the secondary end point of 2-year stroke or systemic embolism. This indicates that the WATCHMAN FLX device has favorable safety and efficacy outcomes.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Clemens Steinwender, Surinder Kaur Khelae, Christophe Garweg, Joseph Yat Sun Chan, Philippe Ritter, Jens Brock Johansen, Venkata Sagi, Laurence M. Epstein, Jonathan P. Piccini, Mario Pascual, Lluis Mont, Todd Sheldon, Vincent Splett, Kurt Stromberg, Nicole Wood, Larry Chinitz
JACC-CLINICAL ELECTROPHYSIOLOGY
(2020)