Isolation, identification, structural elucidation, and toxicity prediction using (Q)-SAR models of two degradants: AQbD-driven LC method to determine the Roxadustat impurities
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Isolation, identification, structural elucidation, and toxicity prediction using (Q)-SAR models of two degradants: AQbD-driven LC method to determine the Roxadustat impurities
Authors
Keywords
-
Journal
Talanta Open
Volume 7, Issue -, Pages 100221
Publisher
Elsevier BV
Online
2023-04-27
DOI
10.1016/j.talo.2023.100221
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- QbD‐based stability‐indicating liquid chromatography (RP‐HPLC) method for the determination of flurbiprofen in cataplasm
- (2023) Rathnakar Nathi et al. BIOMEDICAL CHROMATOGRAPHY
- Implementation of analytical quality by design and green chemistry principles to develop an ultra-high performance liquid chromatography method for the determination of Fluocinolone Acetonide impurities from its drug substance and topical oil formulations
- (2022) Siva Krishna Muchakayala et al. JOURNAL OF CHROMATOGRAPHY A
- Liquid chromatography-tandem mass spectrometry methods for quantification of roxadustat (FG-4592) in human plasma and urine and the applications in two clinical pharmacokinetic studies
- (2022) Xin Zheng et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- A quantitative nuclear magnetic resonance spectroscopic method development and validation to determine an absolute amount of levofloxacin hemihydrate in tablet dosage form
- (2022) Srinivas Nakka et al. Journal of the Iranian Chemical Society
- AQbD based green UPLC method to determine mycophenolate mofetil impurities and Identification of degradation products by QToF LCMS
- (2022) Siva Krishna Muchakayala et al. Scientific Reports
- Whether Prolyl Hydroxylase Blocker—Roxadustat—In the Treatment of Anemia in Patients with Chronic Kidney Disease Is the Future?
- (2021) Władysław Grzeszczak et al. International Journal of Environmental Research and Public Health
- A Randomized Trial of Roxadustat in Anemia of Kidney Failure: SIERRAS Study
- (2021) Chaim Charytan et al. Kidney International Reports
- Phase 3 Study of Roxadustat to Treat Anemia in Non–Dialysis-Dependant CKD
- (2021) Tadao Akizawa et al. Kidney International Reports
- Hypoxia-Inducible Factor Stabilization as an Emerging Therapy for CKD-Related Anemia: Report From a Scientific Workshop Sponsored by the National Kidney Foundation
- (2021) Jay B. Wish et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Eco-friendly and green chromatographic method for the simultaneous determination of chlorocresol and betamethasone dipropionate in topical formulations using Box–Behnken design
- (2021) Siva Krishna Muchakayala et al. Journal of the Iranian Chemical Society
- Roxadustat Does Not Affect Platelet Production, Activation, and Thrombosis Formation
- (2021) Jiaxin Zhao et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- UPLC–MS-Based Procedures to Detect Prolyl-hydroxylase Inhibitors of HIF in Urine
- (2020) Monica Mazzarino et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Inhibition of HIF prolyl-hydroxylase domain to correct anemia in patients with chronic kidney disease
- (2020) Christina M. Wyatt et al. KIDNEY INTERNATIONAL
- Analytical profiling and stability evaluation of liposomal drug delivery systems: A rapid UHPLC-CAD-based approach for phospholipids in research and quality control
- (2020) Florian Weber et al. TALANTA
- Roxadustat for Chronic Kidney Disease-related Anemia in Non-dialysis Patients
- (2020) Daniel W. Coyne et al. Kidney International Reports
- Roxadustat and Anemia of Chronic Kidney Disease
- (2019) Joshua Kaplan NEW ENGLAND JOURNAL OF MEDICINE
- Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis
- (2019) Nan Chen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis
- (2019) Nan Chen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Development and Optimization of Liquid Chromatography Analytical Methods by Using AQbD Principles: Overview and Recent Advances
- (2019) Tim Tome et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Update on Anemia in ESRD and Earlier Stages of CKD: Core Curriculum 2018
- (2018) Steven Fishbane et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Hypoxia-Inducible Factor and Its Role in the Management of Anemia in Chronic Kidney Disease
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Detection of novel metabolite for roxadustat doping by global metabolomics
- (2018) Daisuke Saigusa et al. JOURNAL OF BIOCHEMISTRY
- Quality by design approach in the development of an ultra-high-performance liquid chromatography method for Bexsero meningococcal group B vaccine
- (2018) Luca Nompari et al. TALANTA
- Roxadustat in the treatment of anaemia in chronic kidney disease
- (2017) Lucia Del Vecchio et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- HIF-prolyl hydroxylases as therapeutic targets in erythropoiesis and iron metabolism
- (2017) Volker H. Haase Hemodialysis International
- Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry
- (2017) Annelie Hansson et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Prolyl hydroxylase domain inhibitors as a novel therapeutic approach against anemia in chronic kidney disease
- (2017) Mai Sugahara et al. KIDNEY INTERNATIONAL
- Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
- (2017) Tzu-Lan Yeh et al. Chemical Science
- Detection by LC–MS/MS of HIF stabilizer FG-4592 used as a new doping agent: Investigation on a positive case
- (2016) C. Buisson et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Cyclodextrin- and solvent-modified micellar electrokinetic chromatography for the determination of captopril, hydrochlorothiazide and their impurities: A Quality by Design approach
- (2016) Benedetta Pasquini et al. TALANTA
- Roxadustat (FG-4592): Correction of Anemia in Incident Dialysis Patients
- (2015) A. Besarab et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- A randomized trial of intravenous and oral iron in chronic kidney disease
- (2015) Rajiv Agarwal et al. KIDNEY INTERNATIONAL
- Recent Advances in Developing Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylases and Their Therapeutic Implications
- (2015) So Kim et al. MOLECULES
- Pharmaceutical impurities and degradation products: Uses and applications of NMR techniques
- (2014) Rubén M. Maggio et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Forced degradation and impurity profiling: Recent trends in analytical perspectives
- (2013) Deepti Jain et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now