Article
Clinical Neurology
Julian Klingbeil, Max-Lennart Brandt, Max Wawrzyniak, Anika Stockert, Hans R. Schneider, Petra Baum, Karl-Titus Hoffmann, Dorothee Saur
Summary: Lesions in the left ventrolateral prefrontal cortex increase the risk of depressive symptoms 6 months poststroke, while lesions within the right hemisphere are unrelated to depressive symptoms. Early prediction factors for poststroke depression include depressive symptoms within the first 4 weeks poststroke.
Article
Chemistry, Multidisciplinary
Yajie Zhao, Xiao Xiao, Man Zou, Binbin Ding, Hui Xiao, Meifang Wang, Fan Jiang, Ziyong Cheng, Ping'an Ma, Jun Lin
Summary: Biocatalytic nanomaterials, specifically GHZD NCs, have been shown to amplify multienzyme-mimic cascade reactions, leading to elevated oxidative stress and efficient immunogenic cell death in tumors, ultimately inhibiting tumor growth and triggering long-lasting immunological memory effects.
ADVANCED MATERIALS
(2021)
Article
Gastroenterology & Hepatology
Shihao Ding, Bingting Yu, Anneke J. van Vuuren
Summary: Research has shown that inhibiting cholesterol synthesis can effectively suppress the replication of rotavirus, while increasing cholesterol production can enhance rotavirus replication. Therefore, cholesterol homeostasis plays a crucial role in the replication of rotavirus.
Article
Chemistry, Multidisciplinary
Kuo Li, Dan Li, Cheng-Hsuan Li, Pengfei Zhuang, Chunmei Dai, Xiangka Hu, Dahao Wang, Yuanye Liu, Xifan Mei, Vincent M. Rotello
Summary: Studies have shown that ultra-small noble metal nanoclusters have comprehensive therapeutic effects for wound healing, promoting cell proliferation and migration while decreasing inflammation.
Article
Computer Science, Artificial Intelligence
Mohammed Alweshah
Summary: This paper introduces the application of classification technique, coronavirus herd immunity optimizer algorithm, probabilistic neural network, and their effectiveness in solving classification problems. The experimental results show that the proposed CHIO-PNN method achieves high classification accuracy on multiple datasets, and it converges faster.
Review
Public, Environmental & Occupational Health
Ling-Hui Zeng, Musaddique Hussain, Shahzada Khurram Syed, Malik Saadullah, Qurratulain Jamil, Ali M. Alqahtani, Taha Alqahtani, Nadia Akram, Imran Ahmad Khan, Sajida Parveen, Tehreem Fayyaz, Mobeen Fatima, Saira Shaukat, Najia Shabbir, Mehwish Fatima, Aisha Kanwal, Muhammad Qasim Barkat, Ximei Wu
Summary: Low- and middle-income countries bear a disproportionately high burden of chronic respiratory diseases, which are closely linked to poverty, infectious diseases, and other non-communicable diseases. The prevention and control of NCDs are identified as an urgent development issue by the WHO, crucial for achieving sustainable development goals by 2030. In this context, finding solutions for the prevention, identification, and management of CRDs in LMICs is crucial for achieving universal health coverage.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Cell Biology
Yuqi Liu, Yundai Chen
Summary: Essential hypertension is a common cardiovascular disease influenced by genetic and environmental factors, including mitochondrial DNA mutations. These mutations alter tRNA structure and lead to metabolic disorders, affecting protein synthesis and oxidative phosphorylation.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Oncology
Yu-Nan Ma, Yong-Gang Hong, Guan-Yu Yu, Si-yuan Jiang, Bo-lun Zhao, An Guo, Yao Wang, Xiao-ming Cui, Li-Qiang Hao, Hao Zheng
Summary: LBX2-AS1 is significantly upregulated in colorectal cancer and positively correlated with aggressive disease characteristics, serving as an independent prognostic indicator. Mechanistically, LBX2-AS1 in CRC is regulated by METTL3-dependent m6A methylation and acts as a ceRNA to promote 5-fluorouracil resistance.
CANCER CELL INTERNATIONAL
(2021)
Article
Cell & Tissue Engineering
Qin He, Jia Song, Chen Cui, Jinbang Wang, Huiqing Hu, Xinghong Guo, Mengmeng Yang, Lingshu Wang, Fei Yan, Kai Liang, Zhaojian Liu, Fuqiang Liu, Zheng Sun, Ming Dong, Xinguo Hou, Li Chen
Summary: Exosomes derived from bone marrow mesenchymal stem cells (bmMSCs) contain miR-146a which acts on the NUMB/beta-catenin signaling pathway to protect against diabetic beta-cell dysfunction, potentially representing a novel therapeutic strategy for type 2 diabetes mellitus.
STEM CELL RESEARCH & THERAPY
(2021)
Article
Computer Science, Artificial Intelligence
Ping Wang, Xiufeng Tan, Guanqin Wang, Jianghong Li, Qiang Su, Changqun Shen, Youxiang Zhang
Summary: Vehicle pollution has a significant impact on the ecosystem, and the hybrid electric motorcycle (HE-M) technology introduced in this paper aims to address the environmental challenges by improving efficiency and reducing emissions.
Article
Biotechnology & Applied Microbiology
Yilu Li, Dan Wang, Zhuoyang Li, Zhi Ouyang
Summary: This study demonstrates that the selective A(2B)AR antagonist PSB0788 plays an important role in promoting the normal development of oligodendrocyte precursor cells (OPCs) in the fetal brain in a maternal inflammation-induced periventricular leukomalacia (PVL) model.
Article
Multidisciplinary Sciences
Yilan Qi, Jun He
Summary: This paper proposes an off-topic detection algorithm by combining LDA and word2vec, which solves the accuracy and efficiency problems in off-topic detection of English compositions. The algorithm models and trains the document using the LDA model and word2vec, calculates the probability weighted sum for each topic and its feature words based on the semantic relationship between topics and words, and selects off-topic compositions by setting a reasonable threshold. Experimental results show that this method is more effective than the vector space model, capable of detecting more off-topic compositions with higher accuracy.
Article
Multidisciplinary Sciences
Sehrish Mushtaq, Muhammad Shafiq, Tehseen Ashraf, Muhammad Saleem Haider, Sagheer Atta, Khalid S. Almaary, Mohammad Soliman Elshikh
Summary: This study utilized NGS technology to analyze the diversity and abundance of bacterial species in citrus groves in Pakistan. The results showed that Proteobacteria, Firmicutes, Bacteroides, Cyanobacteria, and Actinobacteria were the most common genera of bacterial endophytes. The composition of microbial communities varied among different citrus cultivars. NGS technology can help us gain a better understanding of the interactions between plants and microbes.
Article
Biochemistry & Molecular Biology
Dexing Jiang, Feng Wang, Haizi Zhang, Wenwen Gao, Xi Tong, Chuangen Lv, Guoxiang Chen
Summary: The study introduces sorghum genome DNA into rice by spike-stalk injection, resulting in a variant plant with C4 photosynthetic traits. The transgenic plants showed enhanced photosynthetic capacity and productivity, indicating the feasibility of inducing efficient photosynthesis and increasing yield through this approach.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Education & Educational Research
Anar Popandopulo, Nataliia Fominykh, Ainash Kudysheva
Summary: The research shows that special training can significantly improve teachers' metacognitive skills and, consequently, their teaching skills. The study found that the experimental group had significantly higher metacognitive skills scores than the control group, and there was a correlation between exam scores and metacognitive skills scores.
THINKING SKILLS AND CREATIVITY
(2021)
