Article
Psychology, Biological
Antares Basulto-Natividad, Genaro A. Coria-Avila, Gonzalo E. Aranda-Abreu, Jorge Manzo, Rebeca Toledo-Cardenas, Maria Elena Hernandez-Aguilar, Deissy Herrera-Covarrubias
Summary: This study investigated the effects of subchronic hypercaloric and restriction diets on body weight, sexual behavior, serum testosterone, and prostate histology in rats. The results showed that the hypercaloric diet group had increased body weight and lower testosterone levels compared to the restriction diet group. Histological alterations in the prostate were observed only in the hypercaloric diet group, while sexual behavior did not differ significantly between the two diet groups. These findings suggest that subchronic modifications in calorie intake can have significant effects on weight, testosterone levels, and prostate histology, but not on sexual behavior in male rats.
PHYSIOLOGY & BEHAVIOR
(2023)
Article
Physiology
Camila F. de Souza, Larissa Rugila S. Stopa, Andressa B. Martins, Ana Luiza M. Wunderlich, Gabriela Mendicelli Lopes, Flaviane de Fatima Silva, Ayumi Cristina Medeiros Komino, Dimas A. M. Zaia, Cassia Thais B. V. Zaia, Fabio Bessa Lima, Ernane Torres Uchoa
Summary: Lactation overnutrition can lead to obesity and disrupt liver metabolism. Increased levels of glucocorticoids are considered as a mediator for obesity development, and bilateral adrenalectomy can reduce obesity. This study suggests that increased circulating glucocorticoids play a pivotal role in liver and plasma impairments induced by lactation overnutrition in male rats.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Endocrinology & Metabolism
Gabrielle R. Names, Jesse S. Krause, Elizabeth M. Schultz, Frederic Angelier, Charline Parenteau, Cecile Ribout, Thomas P. Hahn, John C. Wingfield
Summary: This study found that Hawaii Amakihi populations have evolved increased resilience to avian malaria due to selection pressure, resulting in higher prolactin levels in infected females. Contrary to predictions, stress-induced corticosterone levels were lower in low elevation birds, suggesting that elevation alone does not determine hormone modulation in Amakihi populations.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Fatemeh Lavaee, Zahra Ranjbar, Mina Jalalian, Mohammad Amin Amiri
Summary: This study evaluated the serum sex hormone levels in patients with recurrent aphthous stomatitis and found that the mean level of DHEA-S was significantly lower in these patients compared to the control group. Additionally, the study showed that the levels of testosterone and progesterone were significantly abnormal in patients with RAS. Age was found to have an impact on the levels of DHEA-S, but not on other hormones.
Article
Andrology
Minpeng Ji, Dan Chen, Xingyi Zhao, Fu Huang, Xiaoju Guan, Xin Wen, Jiexia Wang, Jingjing Shao, Jiajia Xie, Dan Shan, Shuyan Cao, Congde Chen, Haolin Chen
Summary: This study describes a new method to isolate LCs from rat testes in large quantity with high purity and viability. The purified LCs retain their steroidogenic and non-steroidogenic functions, making them valuable for studying the physiology, pharmacology, and toxicology of the cells in vitro.
Article
Urology & Nephrology
Anup Patel
Summary: The study showed that lower baseline serum testosterone levels were significantly associated with worse survival endpoints in hormone naive advanced prostate cancer patients undergoing continuous medical castration. Further well-designed studies are needed to compare continuous androgen deprivation therapy with newer alternatives for optimizing individualized management in these patients.
JOURNAL OF UROLOGY
(2021)
Article
Chemistry, Analytical
Xing Ke, Wenxue Liu, Lisong Shen, Yue Zhang, Wei Liu, Chaofu Wang, Xu Wang
Summary: This study developed an artificial intelligence-based artificial neural network model using multiple protein tumor markers for the early diagnosis of colorectal cancer and precancerous lesions. By combining these markers with an ANN algorithm, a diagnosis model (CA6) was developed with high accuracy. The CA6 model performed better than individual protein tumor indicators and could be utilized for early colorectal lesion screening by incorporating more tumor markers with a larger sample size.
Article
Andrology
Jong Soo Lee, Min Ho Lee, Jae Hyun Kim, Yeon Ji Jo, Jong Hun Shin, Hyun Jun Park
Summary: The study found that there is a correlation between intraocular pressure and serum testosterone levels at different levels of obesity, with testosterone levels showing a significant positive correlation with intraocular pressure in the normal obesity index or body mass index.
WORLD JOURNAL OF MENS HEALTH
(2021)
Article
Environmental Sciences
Dan Chen, Xingyi Zhao, Fu Huang, Xiaoju Guan, Jing Tian, Minpeng Ji, Xin Wen, Jingjing Shao, Jiajia Xie, Jiexia Wang, Haolin Chen
Summary: This study found that low-dose, short-term exposure to BPA during puberty can affect male reproductive function in adult rats by altering hormone levels and gene expression profiles in the pituitary and testes.
ENVIRONMENTAL POLLUTION
(2022)
Article
Urology & Nephrology
Soum D. Lokeshwar, Premal Patel, Richard J. Fantus, Joshua Halpern, Cecilia Chang, Atil Y. Kargi, Ranjith Ramasamy
Summary: A study found that total testosterone (TT) levels have been declining among adolescent and young adult males over the past two decades. Higher body mass index (BMI) was associated with lower TT levels, a trend that remained significant even among men with normal BMI. Further studies are needed to verify these findings.
EUROPEAN UROLOGY FOCUS
(2021)
Article
Endocrinology & Metabolism
Onur Ertunc, Erica Smearman, Qizhi Zheng, Jessica L. Hicks, Jacqueline A. Brosnan-Cashman, Tracy Jones, Carolina Gomes-Alexandre, Levent Trabzonlu, Alan K. Meeker, Angelo M. De Marzo, Christopher M. Heaphy
Summary: The new chromogenic in situ hybridization (Telo-CISH) method allows visualization and quantification of telomere content in human prostate tissues at single cell resolution, avoiding the cumbersome fluorescent assays. It is compatible with standard immunohistochemistry, allowing simultaneous assessment of cell types and telomere status, aiding in the identification of precancerous lesions in the prostate.
Article
Endocrinology & Metabolism
C. Fan, D. Wei, L. Wang, P. Liu, K. Fan, L. Nie, X. Liu, J. Hou, W. Huo, L. Li, X. Li, W. Li, C. Wang, Z. Mao
Summary: The study found that serum testosterone levels in Chinese rural population were negatively associated with dyslipidemia and blood lipid levels. Higher serum testosterone levels were associated with lower odds of dyslipidemia in men. Obesity partially mediated the relationship between serum testosterone and dyslipidemia.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Oncology
Lu Yang, Lei Wang, Yuchuan Tan, Hanli Dan, Peng Xian, Yipeng Zhang, Yong Tan, Meng Lin, Jiuquan Zhang
Summary: This study investigated the value of a novel functional magnetic resonance imaging (MRI) technique, amide proton transfer (APT)-weighted MRI, combined with serum prostate-specific antigen (PSA) levels in differentiating malignant and benign prostate lesions. The results showed that the combination of APTmax, APTmean, ADCmean, and PSAD had the highest diagnostic value.
Article
Gastroenterology & Hepatology
Binghan Jin, Zhaoyuan Wu, Shan Wang, Zhu Yu, Rahim Ullah, Xinyi Liang, Wei Wu, Ke Huang, Yan Ni, Jianbing Wang, Guanping Dong, Junfen Fu
Summary: This study examines the prevalence of non-alcoholic fatty liver disease (NAFLD) in obese Chinese children and investigates the relationship between sex hormones and NAFLD. The study finds a significant difference in NAFLD prevalence between genders in obese children, which is influenced by age, Tanner stage, and fat distribution. Sex hormones are associated with NAFLD prevalence in a gender-specific manner.
HEPATOLOGY INTERNATIONAL
(2023)
Article
Endocrinology & Metabolism
Tao Yang, Ying Liu, Shuzhen Chen, Jiale Tian, Xuyou Zhu, Long Zhang, Wei Wang, Yingyi Qin, Jens Richter, Aseem Anand, Chengdang Xu, Yongnan Chi, Chenyang Wang, Cuidong Bian, Denglong Wu, Zhenfei Li, Shengsong Huang
Summary: Serum prolactin levels can predict the response to abiraterone in patients with mCRPC, and they are positively correlated with the volume of metastatic bone disease.
