Review
Ophthalmology
Maria Grazia Fiorino, Claudia Quaranta-Leoni, Francesco M. Quaranta-Leoni
Summary: This review summarizes the etiopathogenesis, management, and outcomes of various treatments for proximal lacrimal obstructions. Different surgical methods have varying effectiveness based on the location and nature of the obstruction, with optimal choice depending on site identification.
ACTA OPHTHALMOLOGICA
(2021)
Article
Otorhinolaryngology
Victoria Miragall, Jens Oeken, Christian Gueldner
Summary: The study evaluated the short-term surgical results of endonasal endoscopic dacryocystorhinostomy, achieving a success rate of 86.3%. Gender, age, pathogen spectrum, and histopathological results did not significantly impact surgical success, but patients with rheumatic diseases may have lower success rates. Type II diabetes and glaucoma patients had longer hospital stays.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Ran Ben Cnaan, Muhammad Abumanhal, Anat Wengier, Ilan Feldman, Igal Leibovitch, Avraham Abergel
Summary: Lacrimal sac diverticulum is a rare condition with a female predominance. It may be the underlying cause of epiphora and/or dacryocystitis, and endoscopic DCR is an effective approach for symptom resolution in these cases.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Genetics & Heredity
Jichao Zhou, Yuchen Wang, Yinghong Zhang, Debo You, Yi Wang
Summary: ADULT syndrome is a rare autosomal dominant inherited disease caused by mutations in the TP63 gene, leading to clinical manifestations such as lacrimal duct obstruction. This case report identified additional clinical manifestations of eyelid fusion and abnormal finger development, along with a unique gene mutation site.
FRONTIERS IN GENETICS
(2023)
Article
Ophthalmology
Sang Jae Lee, Kang Min Lee, Minwook Chang
Summary: Preoperative lacrimal endoscopic evaluation allows for direct visualization of the lacrimal duct system, providing a more accurate diagnosis and guiding the selection of the best surgical option. This can lead to better outcomes, potentially changing the traditional management of the LDS paradigm.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Otorhinolaryngology
Shi-En Huang, Cong-Li Geng, Min Wang, Qin Zhang, Hui Li, Mu-Han Shi, Yu-Xiao Wu
Summary: The efficacy of endoscopic DCR for treating NLDO with a small lacrimal sac has been demonstrated. Patients with small lacrimal sacs are more prone to bilateral eye disease and require longer postoperative follow-up.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Engineering, Biomedical
Mali Dai, Kejia Xu, Decheng Xiao, Yujing Zheng, Qinxiang Zheng, Jianliang Shen, Yuna Qian, Wei Chen
Summary: A new type of hydrogel plug has been developed for the treatment of dry eye. This plug has excellent biocompatibility and biodegradability, and can be noninvasively monitored using near-infrared light. In vivo tests have shown that the hydrogel plug can effectively block the lacrimal passages and greatly improve the clinical indicators of dry eye.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Immunology
Behnam Sadeghi, Olle Ringden, Britt Gustafsson, Markus Castegren
Summary: Acute respiratory distress syndrome (ARDS) is a life-threatening lung disease. Mesenchymal stromal cells (MSCs) have been evaluated as a therapy for ARDS, and the use of MSCs for ARDS induced by Covid-19 has shown positive results. Clinical and experimental studies have demonstrated the effectiveness of MSCs in treating sepsis and ARDS.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Medicine, General & Internal
Hassib Chehade, Gabriella Guzzo, Francois Cachat, Samuel Rotman, Daniel Teta, Giuseppe Pantaleo, Salima Sadallah, Amita Sharma, Ivy A. Rosales, Nina Tolkoff-Rubin, Manuel Pascual
Summary: Acute post-infections glomerulonephritis (APIGN) is a common cause of acute glomerulonephritis in children, potentially leading to severe renal failure. Activation of the alternative and terminal complement pathways is common in APIGN, and treatment with eculizumab may help in recovery of renal function.
FRONTIERS IN MEDICINE
(2021)
Article
Otorhinolaryngology
Francesca Pirola, Giuseppe Spriano, Fabio Ferreli, Elena Russo, Matteo Di Bari, Caterina Giannitto, Armando De Virgilio, Giuseppe Mercante, Paolo Vinciguerra, Alessandra Di Maria, Luca Malvezzi
Summary: This study demonstrates that posterior DCR treatment for lacrimal sac mucoceles is effective in achieving resolution of infection and improving symptoms in the majority of cases. However, some patients may still experience social impacts due to lacrimal way malfunctioning after the surgery.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2022)
Review
Chemistry, Multidisciplinary
Angelo Michele Inchingolo, Giuseppina Malcangi, Irene Ferrara, Assunta Patano, Fabio Viapiano, Anna Netti, Daniela Azzollini, Anna Maria Ciocia, Elisabetta de Ruvo, Merigrazia Campanelli, Pasquale Avantario, Antonio Mancini, Francesco Inchingolo, Ciro Gargiulo Isacco, Alberto Corriero, Alessio Danilo Inchingolo, Gianna Dipalma
Summary: MRONJ is a serious drug-related side effect most common in people using antiresorptive and/or angiogenic medications. Treatment options include conservative measures, surgical procedures, and adjuvant therapies. Surgical treatment is emphasized for advanced lesions, while various alternative therapies show promising potential for improving outcomes.
APPLIED SCIENCES-BASEL
(2023)
Article
Medicine, General & Internal
Zhi-Qiang Du, Wen-Juan Ding, Fei Wang, Xiang-Rong Zhou, Tian-Ming Chen
Summary: ERAT is a safe and effective minimally invasive endoscopic procedure for acute appendicitis in patients with coexistent AP, as shown in two cases of moderately severe AP where traditional medical therapy had failed. Both patients experienced fast postoperative recovery with minimal surgical trauma.
WORLD JOURNAL OF CLINICAL CASES
(2021)
Article
Multidisciplinary Sciences
Jing Li, Rui Liu, Mei Sun, Jinjin Wang, Nan Wang, Xuan Zhang, Xin Ge, Jianmin Ma
Summary: The study aimed to analyze the role of the Fc epsilon RI signaling pathway in the pathogenesis of benign lymphoepithelial lesion of lacrimal gland (LGBLEL). Transcriptomic analysis and immunohistochemical staining results supported the important role of the Fc epsilon RI signaling pathway in the pathogenesis of LGBLEL.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Bo Wu, Yang Bai, Shi'an Yu, Xuemin Li, Xiaokang Wu
Summary: This study investigated the safety and feasibility of 3D laparoscopy and intraoperative ultrasound techniques in minimally invasive pancreatic surgery. Three cases of pancreatic tumors were successfully treated with laparoscopic surgery and showed no complications during follow-up.
Article
Environmental Sciences
Yuan Jin, Meiyao Feng, Wanli Ma, Yanhong Wei, Guangshuai Qi, Jiao Luo, Lin Xu, Xinmei Li, Chuanhai Li, Ying Wang, Daochuan Li, Jing Chen, Yanjie Zhao, Yufei Hou, Qianwen Zhao, Lidan Jiang, Mengyue Xie, Yuxin Zheng, Dianke Yu
Summary: Developing the adverse outcome pathway (AOP) framework is a promising approach to identify potential hazards of new chemicals to the environment and human health. Utilizing data from comparative toxicogenomics database (CTD) and Ingenuity Pathway Analysis (IPA) helps in developing reliable and sensible AOPs. This method speeds up AOP development by collecting fragmented bioinformation in published studies efficiently.
ENVIRONMENTAL POLLUTION
(2021)
