Article
Cardiac & Cardiovascular Systems
Liang Dai, Zi-Ming Wang, Zhi-Qiang Xue, Ming He, Yong Yuan, Xue-Qian Shang, Ke-Neng Chen
Summary: Female sex, absence of lymph node metastasis, increased number of lymph nodes dissected, and postoperative adjuvant therapy were associated with better outcomes among patients with primary malignant melanoma of the esophagus (PMME). Additionally, the preoperative diagnosis rate of PMME was low, lymph node metastasis was common even among patients with early-stage tumors.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Oncology
Kyungmi Yang, Yong Chan Ahn, Heerim Nam, Sang Duk Hong, Dongryul Oh, Jae Myoung Noh
Summary: The study investigated the incidence and clinical features of post-radiation nasopharyngeal necrosis (PRNN) and found that the incidence was significantly higher following re-RT than in single RT. Through timely surgical intervention, PRNN can be successfully recovered without compromising patient survival.
Article
Orthopedics
Longjie Wang, Xiaoxi Yang, Hui Wang, Zhongqiang Chen, Chuiguo Sun, Weishi Li
Summary: Pseudomeningocele is a rare complication that occurs after thoracic spinal surgery, often affecting the upper and lower thoracic spine and requiring individualized treatment. Patients with PMC typically experience higher healthcare costs, poorer neurological recovery, and lower patient satisfaction.
INTERNATIONAL ORTHOPAEDICS
(2021)
Article
Oncology
Hui Shen, Yaodong Zhou
Summary: The study analyzed the clinical features, imaging data, pathologic characteristics, treatment, and prognosis of 36 patients with PPL. Most patients had stage IE disease and received surgery, radiotherapy, or chemotherapy, with favorable outcomes in the majority of cases.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
HongLiang Yang, Feng He, Wen Xu, Zeng Cao
Summary: Cancer of unknown primary site (CUPs) is a metastatic syndrome in which the primary tumor cannot be identified. This study retrospectively analyzed the clinical characteristics and treatment of CUPs patients, finding a close correlation between treatment outcomes and prognostic factors.
Article
Gastroenterology & Hepatology
Marina A. Senchukova, Olesya Tomchuk, Elena Shurygina
Summary: The study found that high concentrations of coccoid forms of H. pylori were more commonly associated with diffuse type GC, poorly differentiated GC, and late-stage tumors, and correlated with poorer prognosis. However, there was no clear relationship between the severity of GM contamination by spiral forms of H. pylori and the clinical characteristics and prognosis of GC.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Medicine, General & Internal
Chan Wu, Rongping Dai, Youxin Chen, Xiao Zhang, Zhe Chen
Summary: This study retrospectively reviewed the clinical characteristics, treatments, and prognosis of subretinal proliferation (SRP) in proliferative diabetic retinopathy (PDR) patients. The results showed that SRP was associated with TRD, and most eyes could achieve successful reattachment of the retina after vitrectomy without removal or transection of SRP.
FRONTIERS IN MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Ahmed Sam Beydoun, Kaleigh A. Stabenau, Kenneth W. Altman, Nikki Johnston
Summary: Esophageal adenocarcinoma (EAC) is increasing rapidly and has a poor prognosis, often preceded by Barrett's esophagus (BE). This review provides an overview of BE, EAC, and the progression from BE to EAC. The definition, diagnosis, epidemiology, and risk factors for both conditions are discussed, with special attention given to areas of debate. The progression from BE to EAC is likely driven by inflammatory pathways, pepsin exposure, upregulation of growth factor pathways, and mitochondrial changes. Surveillance is conducted through serial endoscopic evaluation, with shorter intervals recommended for high-risk features.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Oncology
Enrico Moiso, Paolo Provero
Summary: This study systematically investigates the associations between metabolic alterations and other tumor features using a comprehensive collection of data. The results provide a guide for formulating specific mechanistic hypotheses and contribute to our understanding of the role of metabolic alterations in cancer and the development of precision therapeutic strategies.
Article
Oncology
Rirong Qu, Fan Ye, Dehao Tu, Yixin Cai, Xiangning Fu
Summary: This study retrospectively analyzed the clinical features and surgical outcomes of patients with different EGFR mutations diagnosed as SMPLA. The results showed a high discordance of EGFR mutations in SMPLA patients, with a good prognosis for patients with predominantly multiple ground-glass opacity lesions who underwent surgery.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Jizhuang Luo, Bowen Ding, Alessio Campisi, Tangbing Chen, Haohua Teng, Chunyu Ji
Summary: SMARCA4-deficient thoracic tumors are aggressive malignancies that are often diagnosed at an advanced and inoperable stage. The value of pulmonary resection for resectable SMARCA4-deficient thoracic tumors is largely unknown. This study compares the molecular, clinicopathological characteristics, and survival between SMARCA4-dNSCLC and SMARCA4-deficient undifferentiated tumor (SMARCA4-dUT) patients.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Surgery
Kazuaki Matsui, Hirofumi Kawakubo, Satoru Matsuda, Yuki Hirata, Tomoyuki Irino, Kazumasa Fukuda, Rieko Nakamura, Yuko Kitagawa
Summary: This study aims to investigate the recurrence pattern with lung metastasis after esophageal cancer surgery. Salvage surgery and postoperative pneumonia were found to be significantly related to the recurrence pattern with lung metastasis. Patients with lung metastasis alone had better prognosis and early diagnosis is critical.
WORLD JOURNAL OF SURGERY
(2022)
Article
Oncology
Amal Fekkar, Camille Emprou, Christine Lefebvre, Gilbert Ferretti, Olivier Stephanov, Daniel Pissaloux, Anne Mc Leer, Anne-Claire Toffart, Sophie Rousseaux, Saadi Khochbin, Sylvie Lantuejoul, Severine Valmary-Degano
Summary: NUT carcinoma is a rare and aggressive cancer with chromosomal rearrangement of the NUTM1 gene. It can occur in various locations and all age groups, often undiagnosed due to lack of awareness and nonspecific histological presentation. Immunohistochemistry can easily diagnose NC, which has a poor prognosis despite treatment.
Article
Gastroenterology & Hepatology
Chao Wang, Lin Gan, Zhidong Gao, Zhanlong Shen, Kewei Jiang, Yingjiang Ye
Summary: This study retrospectively reviewed the clinicopathological features, surgical outcomes, and long-term survival of patients with young-onset colon cancer (<= 40 years old). The results showed that advanced-stage colon cancer was more common in young patients, and they had lower long-term survival rates. The study revealed differences in clinical features, surgical outcomes, and long-term survival between young and elderly colon cancer patients, warranting further investigation.
BMC GASTROENTEROLOGY
(2023)
Article
Surgery
Bo Ye, Xiaobin Zhang, Yuchen Su, Shuguang Hao, Haohua Teng, Xufeng Guo, Yu Yang, Yifeng Sun, Teng Mao, Zhigang Li
Summary: The study analyzed the pathological characteristics and recurrence patterns of cN0 submucosal esophageal cancer after esophagectomy. It identified factors influencing lymphatic metastasis and long-term recurrence. Endoscopic submucosal resection may be feasible for patients with small tumors, low invasion depth, and high differentiation.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
