Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1

Delayed activation of human microglial cells by high dose ionizing radiation

(2016) Hongxin Chen et al.   BRAIN RESEARCH

Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis

(2016) Yaqiong Zhang et al.   NEUROCHEMICAL RESEARCH

Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways

(2016) Flávia V. Santa-Cecília et al.   NEUROTOXICITY RESEARCH

Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia

(2014) Daniele Mattei et al.   BRAIN BEHAVIOR AND IMMUNITY

Minocycline ameliorates cognitive impairment induced by whole-brain irradiation: an animal study

(2014) Liyuan Zhang et al.   Radiation Oncology

Molecular Pathways: Radiation-Induced Cognitive Impairment

(2013) D. Greene-Schloesser et al.   CLINICAL CANCER RESEARCH

Radiation-Induced Neuroinflammation and Radiation Somnolence Syndrome

(2013) Paola Ballesteros-Zebadua et al.   CNS & Neurological Disorders-Drug Targets

The PPARδ agonist GW0742 inhibits neuroinflammation, but does not restore neurogenesis or prevent early delayed hippocampal-dependent cognitive impairment after whole-brain irradiation

(2013) Caroline I. Schnegg et al.   FREE RADICAL BIOLOGY AND MEDICINE

Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation

(2012) Shin Bi Oh et al.   BRITISH JOURNAL OF PHARMACOLOGY

PPARδ prevents radiation-induced proinflammatory responses in microglia via transrepression of NF-κB and inhibition of the PKCα/MEK1/2/ERK1/2/AP-1 pathway

(2012) Caroline I. Schnegg et al.   FREE RADICAL BIOLOGY AND MEDICINE

The effect of targeted agents on outcomes in patients with brain metastases from renal cell carcinoma treated with Gamma Knife surgery

(2012) D. Clay Cochran et al.   JOURNAL OF NEUROSURGERY

Radiation-induced cognitive impairment-from bench to bedside

(2012) D. Greene-Schloesser et al.   NEURO-ONCOLOGY

Chronic Administration of the Angiotensin-Converting Enzyme Inhibitor, Ramipril, Prevents Fractionated Whole-Brain Irradiation-Induced Perirhinal Cortex-Dependent Cognitive Impairment

(2012) Tammy C. Lee et al.   RADIATION RESEARCH

Irradiation induces regionally specific alterations in pro-inflammatory environments in rat brain

(2010) Won Hee Lee et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

A PPARdelta Agonist Reduces Amyloid Burden and Brain Inflammation in a Transgenic Mouse Model of Alzheimers Disease

(2009) Sergey Kalinin et al.   Current Alzheimer Research

The PPARα Agonist Fenofibrate Preserves Hippocampal Neurogenesis and Inhibits Microglial Activation After Whole-Brain Irradiation

(2009) Sriram Ramanan et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Kukoamine A analogs with lipoxygenase inhibitory activity

(2009) Dimitra Hadjipavlou-Litina et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Emerging roles of peroxisome proliferator-activated receptor-β/δ in inflammation

(2009) David Bishop-Bailey et al.   PHARMACOLOGY & THERAPEUTICS

Role of PPARs in Radiation-Induced Brain Injury

(2009) Sriram Ramanan et al.   PPAR Research

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

PPARα ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-κB and AP-1 pathways

(2008) Sriram Ramanan et al.   FREE RADICAL BIOLOGY AND MEDICINE